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How to get fromMobile to Florenceby bus, plane, bus (Greyhound), or car

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There are 7 ways to get from Mobile to Florence by bus, plane, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Pensacola International Airport, fly to Northwest Alabama Regional Airport

    best
    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Northwest Alabama Regional Airport (MSL)plane plane PNS - MSL
    5h 17m
    $119–382

  2. Drive 316.6 mi

    cheapest
    1. Drive from Mobile to Florencecar car 316.6 mi
    6h 54m
    $58–84

  3. Bus

    1. Take the bus from Mobile Bus Station to Montgomery Intermodal Centerbus bus
    2. Take the bus from Montgomery Intermodal Center to Huntsville, ALbus bus
    3. Take the bus from Huntsville, AL to Florencebus bus
    11h 31m
    $77–143

  4. Fly Mobile Regional Airport to Huntsville International Airport-Carl T Jones Field, bus

    1. Fly from Mobile Regional Airport (MOB) to Huntsville International Airport-Carl T Jones Field (HSV)plane plane MOB - HSV
    2. Take the bus from Huntsville, AL to Florencebus bus
    9h 34m
    $140–497

  5. Bus to Pensacola International Airport, fly to Nashville, drive

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Nashville (BNA)plane plane PNS - BNA
    3. Drive from Nashville-Airport-BNA to Florencecar car
    7h 52m
    $81–363

  6. Bus to Pensacola International Airport, fly to Huntsville International Airport-Carl T Jones Field, bus

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Huntsville International Airport-Carl T Jones Field (HSV)plane plane PNS - HSV
    3. Take the bus from Huntsville, AL to Florencebus bus
    9h 56m
    $138–465

  7. Fly Mobile Regional Airport to Northwest Alabama Regional Airport

    1. Fly from Mobile Regional Airport (MOB) to Northwest Alabama Regional Airport (MSL)plane plane MOB - MSL
    8h 44m
    $107–439

Pensacola International Airport (PNS) to Northwest Alabama Regional Airport (MSL) flights

Calendar2Weekly Planes
Duration1h 25mAverage Duration
Ticket$93Cheapest Price
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Questions & Answers

Map of how to get from Mobile to Florence.ExpandLaunch map view
  • Distance: 373.3 mi
  • Duration: 5h 17m

What companies run services between Mobile, AL, USA and Florence, AL, USA?

You can take a bus from St Francis WB at Joachim to Florence via Govt WB Across from Greyhound, Mobile Bus Station, Montgomery Intermodal Center, Huntsville, AL, and Florence in around 11h 31m. Alternatively, American Airlines, Corporate Flight Management Inc, and Delta fly from Mobile Regional Airport (MOB) to Northwest Alabama Regional Airport (MSL) 3 times a day.

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