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How to get fromMobile to Fort Myersby bus, car, plane, or train

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There are 8 ways to get from Mobile to Fort Myers by bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Mobile to Fort Myersbus bus Houston
    12h 4m
    $110–140

  2. Bus to Pensacola International Airport, fly to Miami International Airport, bus

    cheapest
    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Miami International Airport (MIA)plane plane PNS - MIA
    3. Take the bus from Miami Airport Station to Fort Myers Bus Stopbus bus
    10h 1m
    $91–401

  3. Drive  606.2 mi

    1. Drive from Mobile to Fort Myerscar car 606.2 mi
    10h 39m
    $111–160

  4. Fly Mobile Regional Airport to Ft. Myers

    1. Fly from Mobile Regional Airport (MOB) to Ft. Myers (RSW)plane plane MOB - RSW
    9h 20m
    $102–500

  5. Train to Gulfport-Biloxi Regional Airport, fly to Ft. Myers

    1. Take the train from Mobile Amtrak Sta to Gulfport Amtrak Statrain train
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Ft. Myers (RSW)plane plane GPT - RSW
    9h 1m
    $147–665

  6. Bus to Pensacola International Airport, fly to Ft. Myers

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Ft. Myers (RSW)plane plane PNS - RSW
    9h 39m
    $382–821

  7. Fly Mobile Regional Airport to Sarasota–Bradenton International Airport, bus

    1. Fly from Mobile Regional Airport (MOB) to Sarasota–Bradenton International Airport (SRQ)plane plane MOB - SRQ
    2. Take the bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stopbus bus
    10h 33m
    $130–632

  8. Bus to Pensacola International Airport, fly to Tampa, bus

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Tampa (TPA)plane plane PNS - TPA
    3. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    10h 17m
    $189–478

Mobile Regional Airport (MOB) to Ft. Myers (RSW) flights

Calendar47Weekly Planes
Duration5h 58mAverage Duration
Ticket$98Cheapest Price
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Questions & Answers

Map of how to get from Mobile to Fort Myers.ExpandLaunch map view
  • Distance: 689 mi
  • Duration: 12h 4m

What companies run services between Mobile, AL, USA and Fort Myers, FL, USA?

Omnibus Express operates a bus from Mobile to Fort Myers once daily. Tickets cost $110–140 and the journey takes 12h 4m. Alternatively, Delta, United Airlines, and American Airlines fly from Mobile Regional Airport (MOB) to Ft. Myers (RSW) every 4 hours.

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