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How to get fromMobile to Jefferson Cityby plane, train, bus, car, shuttle, or bus (Greyhound, Flixbus)

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There are 9 ways to get from Mobile to Jefferson City by plane, train, bus, car, shuttle, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mobile Regional Airport to Columbia Regional Airport

    best
    1. Fly from Mobile Regional Airport (MOB) to Columbia Regional Airport (COU)plane plane MOB - COU
    8h 47m
    $189–558

  2. Drive 694.7 mi

    cheapest
    1. Drive from Mobile to Jefferson Citycar car 694.7 mi
    13h 28m
    $127–184

  3. Train, bus

    1. Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain train
    2. Take the bus from New Orleans Bus Station to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Jefferson City Stationtrain train
    22h 48m
    $180–390

  4. Train, bus via Carbondale

    1. Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain train
    2. Take the train from New Orleans Union Passenger Terminal to Carbondaletrain train
    3. Take the bus from Carbondale to St. Louisbus bus
    4. Take the train from St. Louis to Jefferson City Stationtrain train
    24h 36m
    $285–630

  5. Bus to Pensacola International Airport, fly to Lambert–St. Louis International Airport, shuttle

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Lambert–St. Louis International Airport (STL)plane plane PNS - STL
    3. Take a shuttle bus from St Louis International Airport to Jefferson City, Missourishuttle bus
    8h 27m
    $230–638

  6. Bus to Destin–Fort Walton Beach Airport, fly to Lambert–St. Louis International Airport, shuttle

    1. Take the bus from Mobile to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Lambert–St. Louis International Airport (STL)plane plane VPS - STL
    3. Take a shuttle bus from St Louis International Airport to Jefferson City, Missourishuttle bus
    8h
    $334–826

  7. Bus to Destin–Fort Walton Beach Airport, fly to Columbia Regional Airport

    1. Take the bus from Mobile to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Columbia Regional Airport (COU)plane plane VPS - COU
    5h 41m
    $259–616

  8. Bus to Destin–Fort Walton Beach Airport, fly to Midamerica St. Louis Airport, train

    1. Take the bus from Mobile to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Midamerica St. Louis Airport (BLV)plane plane VPS - BLV
    3. Take the train from St. Louis to Jefferson City Stationtrain train
    9h 30m
    $230–598

  9. Bus

    1. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus bus
    2. Take the bus from New Orleans Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Jefferson Citybus bus
    25h 5m
    $167–328

Mobile Regional Airport (MOB) to Columbia Regional Airport (COU) flights

Calendar15Weekly Planes
Duration5h 29mAverage Duration
Ticket$98Cheapest Price
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Questions & Answers

Map of how to get from Mobile to Jefferson City.ExpandLaunch map view
  • Distance: 650.5 mi
  • Duration: 8h 47m

What companies run services between Mobile, AL, USA and Jefferson City, MO, USA?

American Airlines flies from Mobile Regional Airport (MOB) to Columbia Regional Airport (COU) twice daily. Alternatively, you can take a bus from St Joseph SB Near St Louis St to Jefferson City via Govt WB Across from Greyhound, Mobile Bus Station, New Orleans Bus Station, St Louis Bus Station, and Jefferson City in around 25h 5m.

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