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How to get fromMobile to La Crosseby plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or train

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There are 8 ways to get from Mobile to La Crosse by plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mobile Regional Airport to La Crosse

    best
    1. Fly from Mobile Regional Airport (MOB) to La Crosse (LSE)plane plane MOB - LSE
    8h 22m
    $151–550

  2. Bus to Pensacola International Airport, fly to La Crosse

    cheapest
    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to La Crosse (LSE)plane plane PNS - LSE
    10h 37m
    $114–468

  3. Train (Amtrak)

    1. Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain train
    2. Take the train from New Orleans Union Passenger Terminal to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train
    30h 12m
    $340–798

  4. Bus

    1. Take the bus from Mobile Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to La Crossebus bus
    31h 8m
    $215–359

  5. Drive  1,063.6 mi

    1. Drive from Mobile to La Crossecar car 1,063.6 mi
    19h 46m
    $195–281

  6. Fly Mobile Regional Airport to Dane County Regional Airport-Truax Field, bus

    1. Fly from Mobile Regional Airport (MOB) to Dane County Regional Airport-Truax Field (MSN)plane plane MOB - MSN
    2. Take the bus from Madison to La Crossebus bus
    9h 2m
    $209–794

  7. Bus to Destin–Fort Walton Beach Airport, fly to La Crosse

    1. Take the bus from Mobile to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to La Crosse (LSE)plane plane VPS - LSE
    9h 6m
    $213–609

  8. Train, bus

    1. Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain train
    2. Take the train from New Orleans Union Passenger Terminal to Chicago Union Stationtrain train
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to La Crossebus bus
    31h 50m
    $330–738

Mobile to La Crosse by bus

Calendar7Weekly Buses
Duration31h 8mAverage Duration
Ticket$215Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mobile to La Crosse.ExpandLaunch map view
  • Distance: 947.1 mi
  • Duration: 8h 22m

What companies run services between Mobile, AL, USA and La Crosse, WI, USA?

American Airlines, United Airlines, and Delta fly from Mobile Regional Airport (MOB) to La Crosse (LSE) every 4 hours. Alternatively, you can take a train from Mobile, AL to La Crosse Amtrak Station via New Orleans Union Passenger Terminal and Chicago Union Station in around 30h 12m.

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