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How to get fromMobile to La Crosseby bus, plane, train (Amtrak), bus (Greyhound, Flixbus), car, or train

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There are 10 ways to get from Mobile to La Crosse by bus, plane, train (Amtrak), bus (Greyhound, Flixbus), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Destin–Fort Walton Beach Airport, fly to La Crosse

    best
    1. Take the bus from Mobile to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to La Crosse (LSE)plane plane VPS - LSE
    12h 49m
    $213–599

  2. Bus to Pensacola International Airport, fly to La Crosse

    cheapest
    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to La Crosse (LSE)plane plane PNS - LSE
    10h 50m
    $114–441

  3. Train (Amtrak)

    1. Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain train
    2. Take the train from New Orleans Union Passenger Terminal to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train
    30h 12m
    $420–930

  4. Bus

    1. Take the bus from Mobile Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to UW La Crossebus bus
    31h 27m
    $228–421

  5. Drive 1,063.6 mi

    1. Drive from Mobile to La Crossecar car 1,063.6 mi
    19h 46m
    $195–281

  6. Fly Mobile Regional Airport to La Crosse

    1. Fly from Mobile Regional Airport (MOB) to La Crosse (LSE)plane plane MOB - LSE
    11h 13m
    $124–490

  7. Fly Mobile Regional Airport to Dane County Regional Airport-Truax Field, bus

    1. Fly from Mobile Regional Airport (MOB) to Dane County Regional Airport-Truax Field (MSN)plane plane MOB - MSN
    2. Take the bus from Madison to UW La Crossebus bus
    12h 31m
    $183–723

  8. Bus to Destin–Fort Walton Beach Airport, fly to Minneapolis–Saint Paul International Airport, train

    1. Take the bus from Mobile to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Minneapolis–Saint Paul International Airport (MSP)plane plane VPS - MSP
    3. Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain train
    10h 29m
    $261–814

  9. Bus to Pensacola International Airport, fly to Dane County Regional Airport-Truax Field, bus

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Dane County Regional Airport-Truax Field (MSN)plane plane PNS - MSN
    3. Take the bus from Madison to UW La Crossebus bus
    12h 4m
    $167–675

  10. Train, bus

    1. Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain train
    2. Take the train from New Orleans Union Passenger Terminal to Chicago Union Stationtrain train
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to La Crossebus bus
    32h 11m
    $390–850

Destin–Fort Walton Beach Airport (VPS) to La Crosse (LSE) flights

Calendar12Weekly Planes
Duration11h 26mAverage Duration
Ticket$97Cheapest Price
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Questions & Answers

Map of how to get from Mobile to La Crosse.ExpandLaunch map view
  • Distance: 1,101.4 mi
  • Duration: 12h 49m

What companies run services between Mobile, AL, USA and La Crosse, WI, USA?

You can take a train from Mobile, AL to La Crosse Amtrak Station via New Orleans Union Passenger Terminal and Chicago Union Station in around 30h 12m. Alternatively, you can take a bus from St Joseph SB Near St Louis St to UW La Crosse via Govt WB Across from Greyhound, Mobile Bus Station, Atlanta Bus Station, Chicago Bus Station, Milwaukee Intermodal Station, and Milwaukee in around 31h 27m.

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