There are 5 ways to get from Mobile to Lafayette by bus, car, plane, taxi, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via Mobile
best- Take the bus from Mobile to Opelika 4th Street Stationbus Houston
5h 8m$149–194Drive 244.6 mi
cheapest- Drive from Mobile to Lafayettecar 244.6 mi
4h 8m$42–61Fly to Columbus Airport, taxi
- Fly from Mobile Regional Airport (MOB) to Columbus Airport (CSG)plane MOB - CSG
- Take the taxi from Columbus Airport (CSG) to Lafayettetaxi
5h 41m$197–517Bus (Greyhound)
- Take the bus from Mobile Bus Station to Opelika 4th Street Stationbus Greyhound US0602 / ...
6h 11m$93–128Fly to Hartsfield-Jackson Atlanta International Airport, bus
- Fly from Mobile Regional Airport (MOB) to Hartsfield-Jackson Atlanta International Airport (ATL)plane MOB - ATL
- Take the bus from Atlanta Airport to Hampton Inn & Suites Valleybus
4h 24m$156–517
Mobile Regional Airport (MOB) to Columbus Airport (CSG) flights
Comparing Your Travel Options
The cheapest way to get from Mobile to Lafayette is to drive which costs $40 - $65 and takes 4h 8m.
The fastest way to get from Mobile to Lafayette is to drive which takes 4h 8m and costs $40 - $65.
No, there is no direct bus from Mobile to Lafayette station. However, there are services departing from Mobile and arriving at Opelika 4th Street Station via Mobile. The journey, including transfers, takes approximately 5h 8m.
The distance between Mobile and Lafayette is 270 miles. The road distance is 246.1 miles.
The best way to get from Mobile to Lafayette without a car is to bus via Mobile which takes 5h 8m and costs $140 - $200.
It takes approximately 5h 8m to get from Mobile to Lafayette, including transfers.
Mobile to Lafayette bus services, operated by Omnibus Express, depart from Mobile station.
Mobile to Lafayette bus services, operated by Omnibus Express, arrive at Opelika 4th Street Station.
Yes, the driving distance between Mobile to Lafayette is 246 miles. It takes approximately 4h 8m to drive from Mobile to Lafayette.
There are 12+ hotels available in Lafayette.
What companies run services between Mobile, AL, USA and Lafayette, AL, USA?
Omnibus Express operates a bus from Mobile to Opelika 4th Street Station once daily. Tickets cost $60–80 and the journey takes 3h 19m.
- Website
- delta.com
Flights from Mobile Regional Airport to Columbus Airport via Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 5h 59m
- When
- Every day
- Estimated price
- $55–340
Flights from Mobile Regional Airport to Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $55–380
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Mobile to Opelika 4th Street Station
- Ave. Duration
- 3h 19m
- Frequency
- Once daily
- Estimated price
- $60–80
- Schedules at
- Omnibus Express
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Mobile Bus Station to Opelika 4th Street Station
- Ave. Duration
- 4h 25m
- Frequency
- Twice daily
- Estimated price
- $40–65
- Website
- Greyhound
- Phone
- +1 (334) 821-3399
- [email protected]
- Website
- Groome Transportation
Bus from Atlanta Airport to Hampton Inn & Suites Valley
- Ave. Duration
- 1h 20m
- Frequency
- Every 3 hours
- Estimated price
- $40–65
- Website
- Groome Transportation
- Schedules at
- Groome Transportation Auburn
- Ave. Duration
- 59 min
- Estimated price
- $110–140
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide