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How to get fromMobile to Lafayetteby train, bus, train (Amtrak), car, plane, bus (Flixbus), or bus (Greyhound)

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There are 8 ways to get from Mobile to Lafayette by train, bus, train (Amtrak), car, plane, bus (Flixbus), or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Mobile Amtrak Sta to Biloxi Amtrak Statrain train Amtrak Mardi Gras Service / ...
    2. Take the bus from Biloxi to Lafayettebus bus Atlanta
    5h 18m
    $74–113

  2. Bus via Lafayette Transit System (Greyhound)

    cheapest
    1. Take the bus from Mobile Bus Station to Lafayette Transit Systembus bus Greyhound US0602 / ...
    8h 57m
    $40–85

  3. Train (Amtrak)

    1. Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain train Mobile / ...
    2. Take the train from New Orleans Union Passenger Terminal to Lafayette Amtrak Stationtrain train Sunset Limited
    8h 7m
    $75–190

  4. Drive 254.6 mi

    1. Drive from Mobile to Lafayettecar car 254.6 mi
    4h 13m
    $47–68

  5. Train to Gulfport-Biloxi Regional Airport, fly

    1. Take the train from Mobile Amtrak Sta to Gulfport Amtrak Statrain train
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Lafayette Regional Airport (LFT)plane plane GPT - LFT
    6h 39m
    $129–538

  6. Bus (Flixbus)

    1. Take the bus from Mobile Bus Station to Lafayettebus bus FlixBus N2210
    6h 47m
    $45–80

  7. Fly from Mobile Regional Airport

    1. Fly from Mobile Regional Airport (MOB) to Lafayette Regional Airport (LFT)plane plane MOB - LFT
    7h 19m
    $81–381

  8. Bus to Pensacola International Airport, fly

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Lafayette Regional Airport (LFT)plane plane PNS - LFT
    7h 47m
    $80–361

Mobile to Lafayette by bus (Flixbus)

Calendar6Weekly Buses
Duration6h 47mAverage Duration
Ticket$45Cheapest Price
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Questions & Answers

Map of how to get from Mobile to Lafayette.ExpandLaunch map view
  • Distance: 268.8 mi
  • Duration: 5h 18m

What companies run services between Mobile, AL, USA and Lafayette, LA, USA?

You can take a train from Mobile, AL to Lafayette Amtrak Station via New Orleans Union Passenger Terminal in around 8h 7m. Alternatively, Flixbus USA operates a bus from Mobile Bus Station to Lafayette 6 times a week. Tickets cost $45–80 and the journey takes 5h 10m.

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