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How to get fromMobile to Louisvilleby bus, plane, bus (Greyhound, Amtrak), car, train, or bus (Greyhound)

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There are 8 ways to get from Mobile to Louisville by bus, plane, bus (Greyhound, Amtrak), car, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Destin–Fort Walton Beach Airport, fly to Louisville International Airport

    best
    1. Take the bus from Mobile to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Louisville International Airport (SDF)plane plane VPS - SDF
    6h 6m
    $185–609

  2. Bus to Pensacola International Airport, fly to Louisville International Airport

    cheapest
    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Louisville International Airport (SDF)plane plane PNS - SDF
    8h 8m
    $85–460

  3. Bus

    1. Take the bus from Mobile Bus Station to Montgomery Intermodal Centerbus bus
    2. Take the bus from Montgomery Intermodal Center to Nashville Bus Stationbus bus
    3. Take the bus from Nashville to Louisville, KYbus bus
    15h 17m
    $97–184

  4. Drive 598 mi

    1. Drive from Mobile to Louisvillecar car 598 mi
    10h 58m
    $110–158

  5. Fly Mobile Regional Airport to Louisville International Airport

    1. Fly from Mobile Regional Airport (MOB) to Louisville International Airport (SDF)plane plane MOB - SDF
    7h 54m
    $95–500

  6. Train to Gulfport-Biloxi Regional Airport, fly to Louisville International Airport

    1. Take the train from Mobile Amtrak Sta to Gulfport Amtrak Statrain train
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Louisville International Airport (SDF)plane plane GPT - SDF
    8h 24m
    $159–718

  7. Fly Mobile Regional Airport to Blue Grass Airport, drive

    1. Fly from Mobile Regional Airport (MOB) to Blue Grass Airport (LEX)plane plane MOB - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    8h 35m
    $153–763

  8. Bus via Preston @ Vim

    1. Take the bus from Mobile Bus Station to Montgomery Intermodal Centerbus bus
    2. Take the bus from Montgomery Intermodal Center to Nashville Bus Stationbus bus
    3. Take the bus from Tornado Bus Co - Nashville to La Tropicana - Louisville, KYbus bus
    16h 8m
    $120–289

Mobile to Louisville by bus

Calendar14Weekly Buses
Duration15h 17mAverage Duration
Ticket$97Cheapest Price
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Questions & Answers

Map of how to get from Mobile to Louisville.ExpandLaunch map view
  • Distance: 673.6 mi
  • Duration: 6h 6m

What companies run services between Mobile, AL, USA and Louisville, KY, USA?

You can take a bus from St Joseph SB Near St Louis St to Louisville, KY via Govt WB Across from Greyhound, Mobile Bus Station, Montgomery Intermodal Center, and Nashville in around 15h 17m. Alternatively, Delta, United Airlines, and American Airlines fly from Mobile Regional Airport (MOB) to Louisville International Airport (SDF) every 2 hours.

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