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How to get fromMobile to Orlando Health/Amtrakby plane, bus, train, car, bus (Greyhound), or bus (Amtrak)

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There are 7 ways to get from Mobile to Orlando Health/Amtrak by plane, bus, train, car, bus (Greyhound), or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Mobile Regional Airport

    best
    1. Fly from Mobile Regional Airport (MOB) to Orlando (MCO)plane plane MOB - MCO
    5h 54m
    $116–482
  2. Drive  496.2 mi

    cheapest
    1. Drive from Mobile to Orlando Health/Amtrakcar car 496.2 mi
    8h 1m
    $85–123
  3. Bus, train

    1. Take the bus from Mobile to Plant Citybus bus Houston
    2. Take the train from Lakeland Amtrak Station to Orlandotrain train Floridian
    11h 6m
    $195–254
  4. Train to Gulfport-Biloxi Regional Airport, fly

    1. Take the train from Mobile Amtrak Sta to Gulfport Amtrak Statrain train
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Orlando (MCO)plane plane GPT - MCO
    5h 50m
    $138–533
  5. Bus

    1. Take the bus from Mobile to Tallahasseebus bus Houston
    2. Take the bus from Tallahassee to Orlando Bus Stationbus bus Greyhound US0799 / ...
    11h 34m
    $114–155
  6. Bus via Mccoy Rd & Gondola Dr

    1. Take the bus from Mobile to Tallahasseebus bus Houston
    2. Take the bus from Tallahassee - FSU - Old St Augustine at Intramural Field to Orlando - RedCoach Station, FLbus bus Tallahassee
    11h 54m
    $136–177
  7. Bus, Amtrak Thruway

    1. Take the bus from Mobile to Wildwoodbus bus
    2. Take the bus from Wildwood Amtrak Station to Lakelandbus bus
    3. Take the bus from Lakeland to Orlando, FLbus bus
    13h 10m

Mobile Regional Airport (MOB) to Orlando (MCO) flights

Calendar99Weekly Planes
Duration5h 29mAverage Duration
Ticket$80Cheapest Price
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Comparing Your Travel Options

What companies run services between Mobile, AL, USA and Orlando Health/Amtrak, FL, USA?

Delta, American Airlines, and United Airlines fly from Mobile Regional Airport (MOB) to Orlando (MCO) hourly. Alternatively, you can take a bus from Mobile to Sligh Blvd & W Copeland Dr via Tallahassee, N Monroe Street and Silver Slipper Lane, Tallahassee, Orlando Bus Station, John Young Pkwy & Amelia St, and N Garland Ave & W Amelia St in around 11h 34m.

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Want to know more about travelling around United States

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Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There