There are 3 ways to get from Mobile to Panama City by plane, bus (Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Mobile Regional Airport (MOB) to Tocumen International Airport (PTY)plane MOB - PTY
8h 15m$210–675Bus
- Take the bus from Mobile Bus Station to Downtown Houstonbus
- Take the bus from Houston to San Salvadorbus
- Take the bus from Terminal Tica Bus San Salvador to Terminal Tica Bus San Josébus
- Take the bus from Terminal Tica Bus San José to Terminal Tica Bus Panamábus
5d 2h$384–691Drive 5,059.5 km
- Drive from Mobile to Panama Citycar 5,059.5 km
2d 19h$602–869
Mobile Regional Airport (MOB) to Tocumen International Airport (PTY) flights
Comparing Your Travel Options
The cheapest way to get from Mobile to Panama City is to fly which costs $210 - $700 and takes 8h 15m.
The fastest way to get from Mobile to Panama City is to fly which takes 8h 15m and costs $210 - $700.
No, there is no direct bus from Mobile to Panama City. However, there are services departing from Govt WB and Joachim St and arriving at Terminal Tica Bus Panamá via Mobile Bus Station, Wheeler Station, Houston, Terminal Tica Bus San Salvador and Terminal Tica Bus San José. The journey, including transfers, takes approximately 5 days 2h.
The distance between Mobile and Panama City is 2618 km. The road distance is 5059.5 km.
The best way to get from Mobile to Panama City without a car is to bus which takes 5 days 2h and costs $380 - $700.
It takes approximately 8h 15m to get from Mobile to Panama City, including transfers.
Mobile to Panama City bus services, operated by Flixbus USA, depart from Mobile Bus Station.
The best way to get from Mobile to Panama City is to fly which takes 8h 15m and costs $210 - $700. Alternatively, you can bus, which costs $380 - $700 and takes 5 days 2h.
Mobile to Panama City bus services, operated by Flixbus USA, arrive at Downtown Houston station.
Panama City is 1h ahead of Mobile. It is currently 12:43 AM in Mobile and 1:43 AM in Panama City.
What companies run services between Mobile, AL, USA and Panama City, Panama?
Delta, United Airlines, and Copa Airlines fly from Mobile Regional Airport (MOB) to Tocumen International Airport (PTY) 5 times a day. Alternatively, you can take a bus from Govt WB and Joachim St to Terminal Tica Bus Panamá via Govt WB Across from Greyhound, Mobile Bus Station, Downtown Houston, Wheeler Station, Houston, San Salvador, Terminal Tica Bus San Salvador, and Terminal Tica Bus San José in around 5d 2h.
- Website
- united.com
Flights from Mobile Regional Airport to Tocumen International Airport via Houston
- Ave. Duration
- 9h 50m
- When
- Every day
- Estimated price
- $150–650
Flights from Mobile Regional Airport to Tocumen International Airport via Atlanta
- Ave. Duration
- 6h 59m
- When
- Monday, Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- $140–600
- Website
- copaair.com
Flights from Mobile Regional Airport to Tocumen International Airport via Houston
- Ave. Duration
- 9h 50m
- When
- Every day
- Estimated price
- $150–650
Flights from Mobile Regional Airport to Tocumen International Airport via Atlanta
- Ave. Duration
- 6h 59m
- When
- Monday, Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- $140–600
- Website
- delta.com
Flights from Mobile Regional Airport to Tocumen International Airport via Atlanta
- Ave. Duration
- 7h 2m
- When
- Every day
- Estimated price
- $140–600
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Mobile Bus Station to Downtown Houston
- Ave. Duration
- 8h 50m
- Frequency
- 6 times a week
- Estimated price
- $80–120
- Schedules at
- Flixbus USA
- Phone
- +1 213 368 1172
- [email protected]
- Website
- busesusatours.com
Bus from Houston to San Salvador
- Ave. Duration
- 3d
- Frequency
- Once a week
- Estimated price
- $180–390
- Schedules at
- busesusatours.com
- Phone
- +52 962 625 2435
- [email protected]
- Website
- Tica Bus
Bus from Terminal Tica Bus San Salvador to Terminal Tica Bus San José
- Ave. Duration
- 19h 30m
- Frequency
- 3 times a week
- Estimated price
- $60–90
- Website
- Tica Bus
Bus from Terminal Tica Bus San José to Terminal Tica Bus Panamá
- Ave. Duration
- 16h 10m
- Frequency
- Once daily
- Estimated price
- $55–80
- Website
- Tica Bus
Want to know more about travelling around Panama
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Yes, the driving distance between Mobile to Panama City is 5059 km. It takes approximately 2 days 19h to drive from Mobile to Panama City.
There are 903+ hotels available in Panama City.







