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How to get fromMobile to Panama Cityby plane, train, bus, car, or taxi

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There are 8 ways to get from Mobile to Panama City by plane, train, bus, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Mobile Regional Airport

    best
    1. Fly from Mobile Regional Airport (MOB) to Tocumen International Airport (PTY)plane plane MOB - PTY
    12h
    $188–632

  2. Bus to Pensacola International Airport, fly

    cheapest
    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Tocumen International Airport (PTY)plane plane PNS - PTY
    11h 26m
    $157–514

  3. Train, bus

    1. Take the train from Mobile Amtrak Sta to Biloxi Amtrak Statrain train
    2. Take the bus from Biloxi to Houston - Telephone Rdbus bus
    3. Take the bus from Houston to San Salvadorbus bus
    4. Take the bus from Terminal Tica Bus San Salvador to Terminal Tica Bus San Josébus bus
    5. Take the bus from Terminal Tica Bus San José to Terminal Tica Bus Panamábus bus
    5d 1h
    $413–723

  4. Drive 5,059.5 km

    1. Drive from Mobile to Panama Citycar car 5,059.5 km
    2d 20h
    $693–1,000

  5. Bus to Destin–Fort Walton Beach Airport, fly

    1. Take the bus from Mobile to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Tocumen International Airport (PTY)plane plane VPS - PTY
    11h 34m
    $257–714

  6. Train to Gulfport-Biloxi Regional Airport, fly

    1. Take the train from Mobile Amtrak Sta to Gulfport Amtrak Statrain train
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Tocumen International Airport (PTY)plane plane GPT - PTY
    11h 30m
    $243–800

  7. Train to Louis Armstrong New Orleans International Airport, fly

    1. Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain train
    2. Fly from Louis Armstrong New Orleans International Airport (MSY) to Tocumen International Airport (PTY)plane plane MSY - PTY
    13h 38m
    $220–775

  8. Bus, taxi, taxi to Northwest Florida Beaches International Airport, fly

    1. Take the bus from Mobile to Crestviewbus bus
    2. Take the taxi from Crestview to DeFuniak Springs Courthousetaxi taxi
    3. Take the bus from DeFuniak Springs Courthouse to S. Walton Annexbus bus
    4. Take the taxi from S. Walton Annex to Northwest Florida Beaches International Airport (ECP)taxi taxi
    5. Fly from Northwest Florida Beaches International Airport (ECP) to Tocumen International Airport (PTY)plane plane ECP - PTY
    14h 34m
    $392–904

Mobile Regional Airport (MOB) to Tocumen International Airport (PTY) flights

Calendar40Weekly Planes
Duration8h 36mAverage Duration
Ticket$149Cheapest Price
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Questions & Answers

Map of how to get from Mobile to Panama City.ExpandLaunch map view
  • Distance: 2,633.3 km
  • Duration: 12h

What companies run services between Mobile, AL, USA and Panama City, Panama?

Delta, United Airlines, and Copa Airlines fly from Mobile Regional Airport (MOB) to Tocumen International Airport (PTY) every 4 hours.

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Want to know more about travelling around Panama

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