There are 7 ways to get from Mobile to San Antonio by plane, bus, train (Amtrak), car, train, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Mobile Regional Airport to San Antonio International Airport
best- Fly from Mobile Regional Airport (MOB) to San Antonio International Airport (SAT)plane MOB - SAT
4h 47m$134–589Bus
cheapest- Take the bus from Mobile Bus Station to New Orleans Bus Stationbus Greyhound US0602
- Take the bus from New Orleans Bus Station to San Antonio Bus Stationbus FlixBus 2212
14h 58m$101–164Bus via Houston
- Take the bus from Mobile to Houston - Telephone Rdbus Atlanta
- Take the bus from Houston, TX - 808 Jefferson St to San Antonio, TX - E Commerce Stbus Houston
14h 44m$182–253Train (Amtrak)
- Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain Mobile / ...
- Take the train from New Orleans Union Passenger Terminal to San Antonio Stationtrain Sunset Limited
19h 48m$170–407Drive 661.1 mi
- Drive from Mobile to San Antoniocar 661.1 mi
10h 47m$121–175Train to Gulfport-Biloxi Regional Airport, fly to San Antonio International Airport
- Take the train from Mobile Amtrak Sta to Gulfport Amtrak Statrain
- Fly from Gulfport-Biloxi Regional Airport (GPT) to San Antonio International Airport (SAT)plane GPT - SAT
7h 12m$135–661Fly Mobile Regional Airport to Austin-Bergstrom International Airport, bus
- Fly from Mobile Regional Airport (MOB) to Austin-Bergstrom International Airport (AUS)plane MOB - AUS
- Take the bus from Austin, TX - UT Austin to San Antonio, TX - E Commerce Stbus
7h 59m$137–547
Mobile to San Antonio by bus
Comparing Your Travel Options
The cheapest way to get from Mobile to San Antonio is to bus which costs $100 - $170 and takes 14h 58m.
The fastest way to get from Mobile to San Antonio is to fly which takes 4h 47m and costs $130 - $600.
No, there is no direct bus from Mobile to San Antonio. However, there are services departing from Mobile and arriving at San Antonio, TX - E Commerce St via Mobile, S Wayside Dr @ Telephone Rd and Houston, TX - 808 Jefferson St. The journey, including transfers, takes approximately 14h 44m.
No, there is no direct train from Mobile to San Antonio station. However, there are services departing from Mobile, AL and arriving at San Antonio Station via New Orleans Union Passenger Terminal. The journey, including transfers, takes approximately 19h 48m.
The distance between Mobile and San Antonio is 642 miles. The road distance is 664.9 miles.
The best way to get from Mobile to San Antonio without a car is to bus via Houston which takes 14h 44m and costs $180 - $260.
It takes approximately 4h 47m to get from Mobile to San Antonio, including transfers.
Mobile to San Antonio bus services, operated by Omnibus Express, depart from Mobile station.
Mobile to San Antonio train services, operated by Amtrak, depart from Mobile, AL station.
The best way to get from Mobile to San Antonio is to fly which takes 4h 47m and costs $130 - $600. Alternatively, you can bus via Houston, which costs $180 - $260 and takes 14h 44m, you could also train, which costs $170 - $410 and takes 19h 48m.
What companies run services between Mobile, AL, USA and San Antonio, TX, USA?
United Airlines, American Airlines, and Delta fly from Mobile Regional Airport (MOB) to San Antonio International Airport (SAT) hourly. Alternatively, you can take a bus from Mobile to San Antonio, TX - E Commerce St via Mobile, Houston - Telephone Rd, S Wayside Dr @ Telephone Rd, Mem Hrm Hosp/houston Zoo Stn Nb, Memorial Hermann/Houston Zoo Stn NB, Downtown Transit Center Stn NB, and Houston, TX - 808 Jefferson St in around 14h 44m.
- Website
- aa.com
Flights from Mobile Regional Airport to San Antonio International Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $110–600
Flights from Mobile Regional Airport to San Antonio International Airport via Charlotte
- Ave. Duration
- 7h 1m
- When
- Every day
- Estimated price
- $190–850
Flights from Gulfport-Biloxi Regional Airport to San Antonio International Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- $120–650
Flights from Gulfport-Biloxi Regional Airport to San Antonio International Airport via Charlotte
- Ave. Duration
- 6h 12m
- When
- Every day
- Estimated price
- $220–950
Flights from Mobile Regional Airport to Austin-Bergstrom International Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $95–550
Flights from Mobile Regional Airport to Austin-Bergstrom International Airport via Charlotte
- Ave. Duration
- 7h 22m
- When
- Every day
- Estimated price
- $160–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Mobile, AL to New Orleans, LA - Union Passenger Terminal
- Ave. Duration
- 3h 43m
- Frequency
- Twice daily
- Estimated price
- $30–80
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to San Antonio Station
- Ave. Duration
- 15h 5m
- Frequency
- 3 times a week
- Estimated price
- $140–330
- Website
- Amtrak
Train from Mobile Amtrak Sta to Gulfport Amtrak Sta
- Ave. Duration
- 1h 39m
- Frequency
- Twice daily
- Estimated price
- $18–40
- Website
- Amtrak
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Mobile to Houston - Telephone Rd
- Ave. Duration
- 7h 34m
- Frequency
- Once daily
- Estimated price
- $95–130
- Schedules at
- Omnibus Express
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Booking & Getting There
Mobile to San Antonio bus services, operated by Omnibus Express, arrive at Houston - Telephone Rd station.
Mobile to San Antonio train services, operated by Amtrak, arrive at New Orleans, LA - Union Passenger Terminal station.
Yes, the driving distance between Mobile to San Antonio is 665 miles. It takes approximately 10h 47m to drive from Mobile to San Antonio.
Book your Mobile to San Antonio train tickets online with Omio.
Book your Mobile to San Antonio bus tickets online with Omio.
There are 1334+ hotels available in San Antonio.





