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How to get fromMobile to Sanibel Islandby bus, car, plane, or train

Find Transport to Sanibel Island

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There are 6 ways to get from Mobile to Sanibel Island by bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Mobile to Fort Myersbus bus Houston
    12h 35m
    $172–215
  2. Drive 621.6 mi

    cheapest
    1. Drive from Mobile to Sanibel Islandcar car 621.6 mi
    11h 3m
    $114–164
  3. Fly Mobile Regional Airport to Ft. Myers

    1. Fly from Mobile Regional Airport (MOB) to Ft. Myers (RSW)plane plane MOB - RSW
    7h 55m
    $165–521
  4. Train to Gulfport-Biloxi Regional Airport, fly to Ft. Myers

    1. Take the train from Mobile Amtrak Sta to Gulfport Amtrak Statrain train
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Ft. Myers (RSW)plane plane GPT - RSW
    7h 32m
    $223–705
  5. Bus to Pensacola International Airport, fly to Ft. Myers

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Ft. Myers (RSW)plane plane PNS - RSW
    8h 16m
    $455–908
  6. Bus to Pensacola International Airport, fly to Tampa, bus

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Tampa (TPA)plane plane PNS - TPA
    3. Take the bus from Tampa Airport to Fort Myersbus bus
    9h 4m
    $270–668

Mobile Regional Airport (MOB) to Ft. Myers (RSW) flights

Calendar55Weekly Planes
Duration5h 47mAverage Duration
Ticket$89Cheapest Price
See schedules

Questions & Answers

What companies run services between Mobile, AL, USA and Sanibel Island, FL, USA?

Omnibus Express operates a bus from Mobile to Fort Myers once daily. Tickets cost $110–140 and the journey takes 12h 4m. Alternatively, Delta, American Airlines, and United Airlines fly from Mobile Regional Airport (MOB) to Ft. Myers (RSW) every 4 hours.

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