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How to get fromMobile to Winston-Salemby plane, bus (Greyhound), car, bus, train, or bus (Flixbus, Greyhound)

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There are 9 ways to get from Mobile to Winston-Salem by plane, bus (Greyhound), car, bus, train, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Mobile Regional Airport to Piedmont Triad International Airport

    best
    1. Fly from Mobile Regional Airport (MOB) to Piedmont Triad International Airport (GSO)plane plane MOB - GSO
    7h 46m
    $138–660

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Mobile Bus Station to Atlanta Bus Stationbus bus Greyhound US0602 / ...
    2. Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus bus Greyhound US0670
    14h 32m
    $92–179

  3. Drive 634.8 mi

    1. Drive from Mobile to Winston-Salemcar car 634.8 mi
    11h
    $116–168

  4. Bus to Pensacola International Airport, fly to Piedmont Triad International Airport

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Piedmont Triad International Airport (GSO)plane plane PNS - GSO
    8h 10m
    $123–589

  5. Train to Gulfport-Biloxi Regional Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the train from Mobile Amtrak Sta to Gulfport Amtrak Statrain train
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Charlotte Douglas International Airport (CLT)plane plane GPT - CLT
    3. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    8h 3m
    $146–708

  6. Fly Mobile Regional Airport to Charlotte Douglas International Airport, bus

    1. Fly from Mobile Regional Airport (MOB) to Charlotte Douglas International Airport (CLT)plane plane MOB - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    8h 24m
    $102–552

  7. Bus to Destin–Fort Walton Beach Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the bus from Mobile to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Charlotte Douglas International Airport (CLT)plane plane VPS - CLT
    3. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    8h 9m
    $190–662

  8. Bus to Pensacola International Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Charlotte Douglas International Airport (CLT)plane plane PNS - CLT
    3. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    8h 41m
    $95–492

  9. Bus via Charlotte

    1. Take the bus from Mobile to Atlantabus bus
    2. Take the bus from Atlanta Downtown to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    14h 44m
    $149–242

Mobile to Winston-Salem by bus (Greyhound)

Calendar14Weekly Buses
Duration14h 32mAverage Duration
Ticket$92Cheapest Price
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Questions & Answers

Map of how to get from Mobile to Winston-Salem.ExpandLaunch map view
  • Distance: 653.5 mi
  • Duration: 7h 46m

What companies run services between Mobile, AL, USA and Winston-Salem, NC, USA?

Delta, American Airlines, and United Airlines fly from Mobile Regional Airport (MOB) to Piedmont Triad International Airport (GSO) every 4 hours. Alternatively, you can take a bus from St Joseph SB Near St Louis St to Winston Salem(Trans Center) via Govt WB Across from Greyhound, Mobile Bus Station, and Atlanta Bus Station in around 14h 32m.

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