There are 5 ways to get from Moline to Florence by plane, bus (Greyhound, Flixbus), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Quad City International Airport (MLI) to Florence Regional Airport (FLO)plane MLI - FLO
7h 34m$86–424Bus
- Take the bus from Moline Center Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Florence Bus Stationbus
28h 35m$172–298Bus, train
- Take the bus from Moline Center Station to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain
- Take the train from Petersburg Amtrak Station to Florence Stationtrain
32h 28m$312–753Drive 957.4 mi
- Drive from Moline to Florencecar 957.4 mi
17h 20m$175–253Bus, train via Raleigh
- Take the bus from Moline Center Station to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Raleigh Union Stationtrain
- Take the bus from Raleigh Bus Station to Florence Bus Stationbus
33h 57m$314–737
Moline to Florence by bus
Comparing Your Travel Options
The cheapest way to get from Moline to Florence is to drive which costs $170 - $260 and takes 17h 20m.
The fastest way to get from Moline to Florence is to fly which takes 7h 34m and costs $85 - $430.
No, there is no direct bus from Moline station to Florence station. However, there are services departing from Moline Center Station and arriving at Florence Bus Station via Chicago Bus Station and Atlanta Bus Station. The journey, including transfers, takes approximately 28h 35m.
The distance between Moline and Florence is 785 miles. The road distance is 963 miles.
The best way to get from Moline to Florence without a car is to bus which takes 28h 35m and costs $170 - $300.
It takes approximately 7h 34m to get from Moline to Florence, including transfers.
Moline to Florence bus services, operated by Greyhound USA, depart from Moline Center Station.
The best way to get from Moline to Florence is to fly which takes 7h 34m and costs $85 - $430. Alternatively, you can bus, which costs $170 - $300 and takes 28h 35m.
Moline to Florence bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Florence is 1h ahead of Moline. It is currently 2:24 PM in Moline and 3:24 PM in Florence.
What companies run services between Moline, IL, USA and Florence, SC, USA?
American Airlines flies from Quad City International Airport (MLI) to Florence Regional Airport (FLO) every 4 hours. Alternatively, you can take a bus from Moline Center Station to Florence Bus Station via Chicago Bus Station and Atlanta Bus Station in around 28h 35m.
- Website
- aa.com
Flights from Quad City International Airport to Florence Regional Airport via Charlotte
- Ave. Duration
- 6h 18m
- When
- Every day
- Estimated price
- $75–410
Flights from Quad City International Airport to Florence Regional Airport via Dallas/Ft.Worth, Charlotte
- Ave. Duration
- 11h 8m
- When
- Every day
- Estimated price
- $130–600
Flights from Quad City International Airport to Florence Regional Airport via Chicago O'Hare, Charlotte
- Ave. Duration
- 11h 30m
- When
- Every day
- Estimated price
- $80–430
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Petersburg Amtrak Station
- Ave. Duration
- 21h 1m
- Frequency
- Once daily
- Estimated price
- $220–550
- Website
- Amtrak
Train from Petersburg Amtrak Station to Florence Station
- Ave. Duration
- 5h 8m
- Frequency
- Twice daily
- Estimated price
- $65–160
- Website
- Amtrak
Train from Chicago Union Station to Raleigh Union Station
- Ave. Duration
- 24h 1m
- Frequency
- Once daily
- Estimated price
- $260–650
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Moline Center Station to Chicago Bus Station
- Ave. Duration
- 4h 10m
- Frequency
- 3 times a day
- Estimated price
- $27–45
- Website
- Greyhound
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 16h 5m
- Frequency
- 4 times a day
- Estimated price
- $110–180
- Website
- Greyhound
Bus from Atlanta Bus Station to Florence Bus Station
- Ave. Duration
- 6h 20m
- Frequency
- Twice daily
- Estimated price
- $45–75
- Website
- Greyhound
Bus from Moline Center Station to Chicago Bus Station
- Ave. Duration
- 4h 10m
- Frequency
- 3 times a day
- Estimated price
- $27–45
- Website
- Greyhound
Bus from Moline Center Station to Chicago Bus Station
- Ave. Duration
- 4h 10m
- Frequency
- 3 times a day
- Estimated price
- $27–45
- Website
- Greyhound
Bus from Raleigh Bus Station to Florence Bus Station
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $23–40
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Yes, the driving distance between Moline to Florence is 963 miles. It takes approximately 17h 20m to drive from Moline to Florence.
Book your Moline to Florence bus tickets online with Omio and FlixBus.
There are 46+ hotels available in Florence.





