There are 7 ways to get from Moline to Knoxville by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Quad City International Airport
best- Fly from Quad City International Airport (MLI) to Mcghee Tyson Airport (TYS)plane MLI - TYS
5h 38m$226–1,071Drive 643.6 mi
cheapest- Drive from Moline to Knoxvillecar 643.6 mi
11h 3m$110–159Bus
- Take the bus from Moline Center Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to New York Midtownbus
- Take the bus from New York to Knoxvillebus Nyc
38h 56m$365–540Bus, train
- Take the bus from Moline Center Station to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the bus from New York to Knoxvillebus Nyc
39h 4m$715–1,150Bus to Chicago O'Hare International Airport, fly
- Take the bus from Moline Center Station to Chicago Bus Stationbus
- Fly from Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS)plane ORD - TYS
8h 13m$212–875Bus, train via Ossining
- Take the bus from Moline Center Station to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain
- Take the train from Croton-Harmon to 125th Street - Harlemtrain
- Take the bus from New York, NY to Knoxville, TNbus Ny
39h 42m$680–1,027Bus via Baltimore
- Take the bus from Moline Center Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Baltimore Downtown Bus Stationbus
- Take the bus from Baltimore Downtown Bus Station to Port Authority Bus Terminalbus
- Take the bus from New York to Knoxvillebus Nyc
40h 28m$395–575
Quad City International Airport (MLI) to Mcghee Tyson Airport (TYS) flights
Comparing Your Travel Options
The cheapest way to get from Moline to Knoxville is to drive which costs $110 - $160 and takes 11h 3m.
The fastest way to get from Moline to Knoxville is to fly which takes 5h 38m and costs $220 - $1,100.
No, there is no direct bus from Moline station to Knoxville. However, there are services departing from Moline Center Station and arriving at Knoxville via Chicago Bus Station and New York. The journey, including transfers, takes approximately 38h 56m.
The distance between Moline and Knoxville is 547 miles. The road distance is 647.3 miles.
The best way to get from Moline to Knoxville without a car is to bus which takes 38h 56m and costs $360 - $550.
It takes approximately 5h 38m to get from Moline to Knoxville, including transfers.
Moline to Knoxville bus services, operated by Greyhound USA, depart from Moline Center Station.
The best way to get from Moline to Knoxville is to fly which takes 5h 38m and costs $220 - $1,100. Alternatively, you can bus, which costs $360 - $550 and takes 38h 56m.
Moline to Knoxville bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Knoxville is 1h ahead of Moline. It is currently 8:24 AM in Moline and 9:24 AM in Knoxville.
What companies run services between Moline, IL, USA and Knoxville, TN, USA?
Delta, United Airlines, and two other airlines fly from Quad City International Airport (MLI) to Mcghee Tyson Airport (TYS) every 3 hours. Alternatively, you can take a bus from Moline Center Station to Knoxville via Chicago Bus Station, New York Midtown, 23 St, East Broadway, New York, and Knoxville in around 38h 56m.
- Website
- aa.com
Flights from Quad City International Airport to Mcghee Tyson Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $170–1,000
Flights from Quad City International Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 5h 35m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Quad City International Airport to Mcghee Tyson Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 13m
- When
- Every day
- Estimated price
- $300–1,400
Flights from Chicago O'Hare International Airport to Mcghee Tyson Airport
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- $120–750
Flights from Chicago O'Hare International Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 18m
- When
- Every day
- Estimated price
- $160–850
- Website
- united.com
Flights from Quad City International Airport to Mcghee Tyson Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 31m
- When
- Every day
- Estimated price
- $170–1,000
Flights from Chicago O'Hare International Airport to Mcghee Tyson Airport
- Ave. Duration
- 1h 54m
- When
- Every day
- Estimated price
- $120–750
- Website
- delta.com
Flights from Quad City International Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $200–1,100
Flights from Chicago O'Hare International Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $160–850
- Website
- allegiantair.com
Flights from Quad City International Airport to Mcghee Tyson Airport via St. Petersburg
- Ave. Duration
- 5h 4m
- When
- Saturday
- Estimated price
- $320–1,500
Flights from Quad City International Airport to Mcghee Tyson Airport via Orlando Sanford
- Ave. Duration
- 5h 58m
- When
- Thursday
- Estimated price
- $310–1,400
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 20h 12m
- Frequency
- Once daily
- Estimated price
- $500–850
- Website
- Amtrak
Train from Chicago Union Station to Croton-Harmon Amtrak Station
- Ave. Duration
- 19h 23m
- Frequency
- Once daily
- Estimated price
- $500–800
- Website
- Amtrak
- Phone
- +1 877.690.5114
- Website
- Metro North Railroad
Train from Croton-Harmon to 125th Street - Harlem
- Ave. Duration
- 1h 1m
- Frequency
- Every 20 minutes
- Estimated price
- $10–17
- Website
- Metro North Railroad
- Schedules at
- Metro North Railroad Schedules
- Off-Peak
- $10–12
- Peak
- $14–17
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Moline Center Station to Chicago Bus Station
- Ave. Duration
- 4h 10m
- Frequency
- 5 times a day
- Estimated price
- $30–50
- Website
- Greyhound
Bus from Moline Center Station to Chicago Bus Station
- Ave. Duration
- 4h 10m
- Frequency
- 5 times a day
- Estimated price
- $30–50
- Website
- Greyhound
Bus from Moline Center Station to Chicago Bus Station
- Ave. Duration
- 4h 10m
- Frequency
- 5 times a day
- Estimated price
- $30–50
- Website
- Greyhound
Bus from Moline Center Station to Chicago Bus Station
- Ave. Duration
- 4h 10m
- Frequency
- 5 times a day
- Estimated price
- $30–50
- Website
- Greyhound
Bus from Moline Center Station to Chicago Bus Station
- Ave. Duration
- 4h 10m
- Frequency
- 5 times a day
- Estimated price
- $30–50
- Website
- Greyhound
Bus from Chicago Bus Station to Baltimore Downtown Bus Station
- Ave. Duration
- 17h 45m
- Frequency
- 4 times a day
- Estimated price
- $140–210
- Website
- Greyhound
Bus from Baltimore Downtown Bus Station to Port Authority Bus Terminal
- Ave. Duration
- 3h 20m
- Frequency
- Hourly
- Estimated price
- $40–65
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago Bus Station to New York Midtown
- Ave. Duration
- 20h 10m
- Frequency
- 4 times a day
- Estimated price
- $150–240
- Schedules at
- Flixbus USA
- Phone
- +1 646-630-7186
- [email protected]
- Website
- Wanda Coach
Bus from New York to Knoxville
- Ave. Duration
- 11h 45m
- Frequency
- Once daily
- Estimated price
- $95–140
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $95–140
Bus from New York to Knoxville
- Ave. Duration
- 11h 45m
- Frequency
- Once daily
- Estimated price
- $95–140
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $95–140
Bus from New York to Knoxville
- Ave. Duration
- 11h 45m
- Frequency
- Once daily
- Estimated price
- $95–140
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $95–140
- Phone
- +1 615-939-8887
- [email protected]
- Website
- New York to Tennessee Bus
Bus from New York, NY to Knoxville, TN
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $95–110
- Website
- New York to Tennessee Bus
- Adult One-way
- $95–110
Want to know more about travelling around United States
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Booking & Getting There
Yes, the driving distance between Moline to Knoxville is 647 miles. It takes approximately 11h 3m to drive from Moline to Knoxville.
There are 320+ hotels available in Knoxville.








