There are 4 ways to get from Montepulciano to Isernia by train, bus, train (Trenitalia), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Chiusi-Chianciano T. to Roma Tiburtinatrain 4113 / ...
- Take the bus from Roma, Autostazione Tiburtina to Iserniabus Rome Tiburtina
6h 9m€25–54Train (Trenitalia)
- Take the train from Chiusi-Chianciano T. to Roma Terminitrain 4113 / ...
- Take the train from Roma Termini to Iserniatrain Re
6h 31m€40–67Drive 328.6 km
- Drive from Montepulciano to Iserniacar 328.6 km
3h 26m€53–77Bus, train
- Take the bus from Bettole - Uff.PT Bettolle to Cassinobus
- Take the train from Cassino to Iserniatrain Re
6h 25m€29–41
Montepulciano to Isernia by bus, train, and foot
Comparing Your Travel Options
The cheapest way to get from Montepulciano to Isernia is to bus and train which costs €29 - €45 and takes 6h 25m.
The fastest way to get from Montepulciano to Isernia is to drive which takes 3h 26m and costs €50 - €80.
No, there is no direct train from Montepulciano to Isernia. However, there are services departing from Chiusi-Chianciano T. and arriving at Isernia via Roma Termini. The journey, including transfers, takes approximately 6h 31m.
The distance between Montepulciano and Isernia is 344 km. The road distance is 328.6 km.
The best way to get from Montepulciano to Isernia without a car is to train and bus which takes 6h 9m and costs €25 - €55.
It takes approximately 6h 9m to get from Montepulciano to Isernia, including transfers.
Montepulciano to Isernia train services, operated by Trenitalia, depart from Chiusi-Chianciano T. station.
Montepulciano to Isernia train services, operated by Trenitalia, arrive at Roma Termini station.
Yes, the driving distance between Montepulciano to Isernia is 329 km. It takes approximately 3h 26m to drive from Montepulciano to Isernia.
There are 460+ hotels available in Isernia.
What companies run services between Montepulciano, Tuscany, Italy and Isernia, Italy?
You can take a bus from P.Ta Delle Farine to Isernia via Chiusi Stazione-P.Za Dante, Chiusi-Chianciano T., and Roma Termini in around 6h 31m.
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Chiusi-Chianciano T. to Roma Tiburtina
- Ave. Duration
- 1h 29m
- Frequency
- Hourly
- Estimated price
- €17–24
- Website
- Trenitalia
Train from Chiusi-Chianciano T. to Roma Termini
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- €18–25
- Website
- Trenitalia
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- Every 3 hours
- Estimated price
- €22–35
- Website
- Trenitalia
Train from Cassino to Isernia
- Ave. Duration
- 42 min
- Frequency
- Every 4 hours
- Estimated price
- €6–9
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Chiusi-Chianciano T. to Roma Tiburtina
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- €15–29
- Website
- Trenitalia Intercity
Train from Chiusi-Chianciano T. to Roma Termini
- Ave. Duration
- 2h 30m
- Frequency
- Every 4 hours
- Estimated price
- €16–29
- Website
- Trenitalia Intercity
- Phone
- +39 0874 64744
- [email protected]
- Website
- atm-molise.it
Bus from Roma, Autostazione Tiburtina to Isernia
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Roma, Autostazione Tiburtina to Isernia
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- €14–22
- Website
- Flixbus
- Phone
- +39 089 233 899
- [email protected]
- Website
- Curcio Viaggi
Bus from Bettole - Uff.PT Bettolle to Cassino
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- €21–29
- Website
- Curcio Viaggi
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