There are 3 ways to get from Montepulciano to Isernia by train (Trenitalia), bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Trenitalia)
best- Take the train from Chiusi-Chianciano T. to Roma Terminitrain 4113 / ...
- Take the train from Roma Termini to Iserniatrain Re
6h 57m€40–67Bus
cheapest- Take the bus from Orvieto Scalo to Roma, Autostazione Tiburtinabus N997
- Take the bus from Roma, Autostazione Tiburtina to Iserniabus Rome Tiburtina
7h 39m€24–50Drive 328.6 km
- Drive from Montepulciano to Iserniacar 328.6 km
3h 26m€54–77
Montepulciano to Isernia by bus and train (Trenitalia)
Comparing Your Travel Options
The cheapest way to get from Montepulciano to Isernia is to bus which costs €24 - €50 and takes 7h 39m.
The fastest way to get from Montepulciano to Isernia is to drive which takes 3h 26m and costs €50 - €80.
No, there is no direct bus from Montepulciano to Isernia. However, there are services departing from P.Ta Delle Farine and arriving at Isernia via Orvieto Scalo and Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 7h 39m.
No, there is no direct train from Montepulciano to Isernia. However, there are services departing from Chiusi-Chianciano T. and arriving at Isernia via Roma Termini. The journey, including transfers, takes approximately 6h 57m.
The distance between Montepulciano and Isernia is 361 km. The road distance is 328.6 km.
The best way to get from Montepulciano to Isernia without a car is to train which takes 6h 57m and costs €40 - €70.
It takes approximately 6h 57m to get from Montepulciano to Isernia, including transfers.
Montepulciano to Isernia bus services, operated by FlixBus, depart from Orvieto Scalo station.
Montepulciano to Isernia train services, operated by Trenitalia, depart from Chiusi-Chianciano T. station.
The best way to get from Montepulciano to Isernia is to train which takes 6h 57m and costs €40 - €70. Alternatively, you can bus, which costs €24 - €50 and takes 7h 39m.
What companies run services between Montepulciano, Tuscany, Italy and Isernia, Italy?
You can take a bus from P.Ta Delle Farine to Isernia via Chiusi Stazione-P.Za Dante, Chiusi-Chianciano T., and Roma Termini in around 6h 57m. Alternatively, you can take a bus from P.Ta Delle Farine to Isernia via Chiusi Stazione-P.Za Dante, Chiusi-Chianciano T., Orvieto, Orvieto Scalo, and Roma, Autostazione Tiburtina in around 7h 39m.
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Chiusi-Chianciano T. to Roma Termini
- Ave. Duration
- 2h 1m
- Frequency
- Every 4 hours
- Estimated price
- €17–25
- Website
- Trenitalia
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- 5 times a day
- Estimated price
- €22–35
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Chiusi-Chianciano T. to Roma Termini
- Ave. Duration
- 2h 30m
- Frequency
- 3 times a day
- Estimated price
- €16–29
- Website
- Trenitalia Intercity
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Orvieto Scalo to Roma, Autostazione Tiburtina
- Ave. Duration
- 1h 30m
- Frequency
- 4 times a week
- Estimated price
- €10–16
- Website
- Flixbus
Bus from Roma, Autostazione Tiburtina to Isernia
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- €15–23
- Website
- Flixbus
- Phone
- +39 0874 64744
- [email protected]
- Website
- atm-molise.it
Bus from Roma, Autostazione Tiburtina to Isernia
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
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Booking & Getting There
Montepulciano to Isernia bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
Montepulciano to Isernia train services, operated by Trenitalia, arrive at Roma Termini station.
Yes, the driving distance between Montepulciano to Isernia is 329 km. It takes approximately 3h 26m to drive from Montepulciano to Isernia.
There are 459+ hotels available in Isernia.