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How to get fromMontepulciano to Iserniaby train (Trenitalia), bus, or car

Find Transport to Isernia

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There are 3 ways to get from Montepulciano to Isernia by train (Trenitalia), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Trenitalia)

    best
    1. Take the train from Chiusi-Chianciano T. to Roma Terminitrain train 4105 / ...
    2. Take the train from Roma Termini to Iserniatrain train Re
    6h 48m
    €41–78
  2. Bus

    cheapest
    1. Take the bus from Orvieto Scalo to Roma, Autostazione Tiburtinabus bus N997
    2. Take the bus from Roma, Autostazione Tiburtina to Iserniabus bus Rome Tiburtina
    7h 18m
    €24–54
  3. Drive 328.6 km

    1. Drive from Montepulciano to Iserniacar car 328.6 km
    3h 26m
    €52–75

Montepulciano to Isernia by bus and train (Trenitalia)

Calendar70Weekly Services
Duration6h 48mAverage Duration
Ticket€41Cheapest Price
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Questions & Answers

What companies run services between Montepulciano, Tuscany, Italy and Isernia, Italy?

You can take a bus from P.Ta Delle Farine to Isernia via Chiusi Stazione-P.Za Dante, Chiusi-Chianciano T., and Roma Termini in around 6h 48m. Alternatively, you can take a bus from P.Ta Delle Farine to Isernia via Chiusi Stazione-P.Za Dante, Chiusi-Chianciano T., Orvieto, Orvieto Scalo, and Roma, Autostazione Tiburtina in around 7h 18m.

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