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How to get fromMontepulciano to Iserniaby bus, train, train (Trenitalia), or car

Find Transport to Isernia

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There are 5 ways to get from Montepulciano to Isernia by bus, train, train (Trenitalia), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Bettole - Uff.PT Bettolle to Cassinobus bus
    2. Take the train from Cassino to Iserniatrain train Re
    6h 25m
    €29–41

  2. Bus

    cheapest
    1. Take the bus from Orvieto Scalo to Roma, Autostazione Tiburtinabus bus N997
    2. Take the bus from Roma, Autostazione Tiburtina to Iserniabus bus Rome Tiburtina
    7h 37m
    €24–50

  3. Train (Trenitalia)

    1. Take the train from Chiusi-Chianciano T. to Roma Tiburtinatrain train 4113 / ...
    2. Take the train from Roma Tiburtina to Iserniatrain train Re
    6h 31m
    €40–62

  4. Drive  328.6 km

    1. Drive from Montepulciano to Iserniacar car 328.6 km
    3h 26m
    €60–86

  5. Train via Rome (Trenitalia)

    1. Take the train from Chiusi-Chianciano T. to Roma Terminitrain train 4113 / ...
    2. Take the train from Roma Termini to Iserniatrain train Re
    6h 57m
    €40–62

Montepulciano to Isernia by bus, foot, and train

Calendar7Weekly Services
Duration6h 25mAverage Duration
Ticket€29Cheapest Price
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Comparing Your Travel Options

Map of how to get from Montepulciano to Isernia.ExpandLaunch map view
  • Distance: 367 km
  • Duration: 6h 25m

What companies run services between Montepulciano, Tuscany, Italy and Isernia, Italy?

You can take a bus from P.Ta Delle Farine to Isernia via Chiusi Stazione-P.Za Dante, Chiusi-Chianciano T., and Roma Tiburtina in around 6h 31m. Alternatively, you can take a bus from P.Ta Delle Farine to Isernia via Chiusi Stazione-P.Za Dante, Chiusi-Chianciano T., Orvieto, Orvieto Scalo, and Roma, Autostazione Tiburtina in around 7h 37m.

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