There are 5 ways to get from Morona-Santiago to Guayaquil by bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Macas to Cuencabus Macas
- Take the bus from Cuenca to Terminal Terrestre de Guayaquilbus Cuenca
5h 30m$18–49Bus #2
cheapest- Take the bus from Macas to Terminal Terrestre de Guayaquilbus Macas
7h 10m$12–22Drive 320.5 km
- Drive from Macas to Guayaquilcar 320.5 km
5h 45m$19–27Bus, fly
- Take the bus from Macas to Cuencabus
- Fly from Cuenca (CUE) to José Joaquín De Olmedo International Airport (GYE)plane CUE - GYE
3h 44m$90–194Bus via Cuenca
- Take the bus from Macas to Cuencabus Macas
- Take the bus from Cuenca to Terminal Terrestre de Guayaquilbus Cuenca
6h 5m$20–24
Morona-Santiago to Guayaquil by bus
Questions & Answers
The cheapest way to get from Morona-Santiago to Guayaquil is to bus which costs $12 - $22 and takes 7h 10m.
The fastest way to get from Morona-Santiago to Guayaquil is to bus and fly which takes 3h 44m and costs $85 - $200.
Yes, there is a direct bus departing from Macas and arriving at Terminal Terrestre de Guayaquil. Services depart every four hours, and operate every day. The journey takes approximately 7h 10m.
The distance between Morona-Santiago and Guayaquil is 437 km. The road distance is 320.5 km.
The best way to get from Morona-Santiago to Guayaquil without a car is to bus which takes 5h 30m and costs $17 - $50.
It takes approximately 5h 30m to get from Morona-Santiago to Guayaquil, including transfers.
Morona-Santiago to Guayaquil bus services, operated by Cooperativa de Transportes MACAS, depart from Macas station.
Morona-Santiago to Guayaquil bus services, operated by Cooperativa de Transportes MACAS, arrive at Cuenca station.
Yes, the driving distance between Morona-Santiago to Guayaquil is 320 km. It takes approximately 5h 45m to drive from Morona-Santiago to Guayaquil.
There are 455+ hotels available in Guayaquil.
What companies run services between Morona-Santiago, Ecuador and Guayaquil, Ecuador?
You can take a bus from Macas to Terminal Terrestre de Guayaquil via Cuenca in around 5h 30m.
- Website
- latam.com
Flights from Cuenca to José Joaquín De Olmedo International Airport
- Ave. Duration
- 45 min
- When
- Monday, Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- $80–180
- Phone
- +593 0994201601
- [email protected]
- Website
- facebook.com
Bus from Macas to Cuenca
- Ave. Duration
- 1h 50m
- Frequency
- 4 times a day
- Estimated price
- $10–15
- Schedules at
- facebook.com
Bus from Macas to Cuenca
- Ave. Duration
- 1h 50m
- Frequency
- 4 times a day
- Estimated price
- $10–15
- Schedules at
- facebook.com
Bus from Macas to Cuenca
- Ave. Duration
- 1h 50m
- Frequency
- 4 times a day
- Estimated price
- $10–15
- Schedules at
- facebook.com
Bus from Macas to Terminal Terrestre de Guayaquil
- Ave. Duration
- 9h
- Frequency
- 4 times a day
- Estimated price
- $12–20
- Schedules at
- facebook.com
- Phone
- +593 3-274-0070
- [email protected]
Bus from Macas to Cuenca
- Ave. Duration
- 1h 2m
- Frequency
- Twice daily
- Estimated price
- $9–13
- Schedules at
- transportesamazonas.com.ec
- Book at
- busplace.com
Bus from Macas to Cuenca
- Ave. Duration
- 1h 2m
- Frequency
- Twice daily
- Estimated price
- $9–13
- Schedules at
- transportesamazonas.com.ec
- Book at
- busplace.com
Bus from Macas to Cuenca
- Ave. Duration
- 1h 2m
- Frequency
- Twice daily
- Estimated price
- $9–13
- Schedules at
- transportesamazonas.com.ec
- Book at
- busplace.com
- Phone
- +593 99 144 1474
- [email protected]
- Website
- facebook.com
Bus from Cuenca to Terminal Terrestre de Guayaquil
- Ave. Duration
- 3h 30m
- Frequency
- Hourly
- Estimated price
- $8–11
- Schedules at
- facebook.com
- Book at
- ecuabuses.com
- Phone
- +593 7-282-4005
- Website
- facebook.com
Bus from Cuenca to Terminal Terrestre de Guayaquil
- Ave. Duration
- 4h 15m
- Frequency
- Hourly
- Estimated price
- $8–13
- Schedules at
- facebook.com
- Phone
- +593 98 453 6454
- [email protected]
- Website
- facebook.com
Bus from Cuenca to Terminal Terrestre de Guayaquil
- Ave. Duration
- 4h 15m
- Frequency
- Hourly
- Estimated price
- $11–35
- Book at
- redbus.pe
- Phone
- +593 98 731 4698
- [email protected]
Bus from Cuenca to Terminal Terrestre de Guayaquil
- Ave. Duration
- 3h 15m
- Frequency
- Hourly
- Estimated price
- $10
- Schedules at
- facebook.com
Bus from Macas to Terminal Terrestre de Guayaquil
- Ave. Duration
- 7h 10m
- Frequency
- 3 times a day
- Estimated price
- $12–22
- Schedules at
- Riobamba Cooperativa de Transportes
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