There are 7 ways to get from Mosbach to Prague by bus, train, night train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Neckarsulm station west to Praguebus N109
8hKč 950–1,400Train
- Take the train from Osterburken to Wuerzburg Hbftrain Re
- Take the train from Würzburg Hbf to Nürnberg Hbftrain 25 / ...
- Take the train from Nürnberg Hbf to Schwandorftrain
- Take the train from Schwandorf to Praha Hlavni Nadrazitrain Re
8h 57mKč 2,506–7,913Train, night train
- Take the train from Mosbach, Bahnhof to Mannheim, Hauptbahnhoftrain S2 / ...
- Take the nighttrain from Mannheim Hbf to Praha Hlavni Nadrazinighttrain En
11h 59mKč 3,930–7,346Drive 452.8 km
- Drive from Mosbach to Praguecar 452.8 km
4h 15mKč 1,750–2,527Train, bus
- Take the train from Mosbach, Bahnhof to Heidelberg, Hauptbahnhoftrain S2 / ...
- Take the bus from Heidelberg to Prague - Florenc Main Bus Terminalbus BlaBlaCar Bus
8h 47mKč 1,152–2,525Train to Stuttgart Airport, fly
- Take the train from Bad Friedrichshall Hbf to Stuttgart Hbftrain
- Fly from Stuttgart Airport (STR) to Václav Havel Airport Prague (PRG)plane STR - PRG
7h 15mKč 2,932–8,116Train, train to Frankfurt, fly
- Take the train from Mosbach, Bahnhof to Mannheim, Hauptbahnhoftrain
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Václav Havel Airport Prague (PRG)plane FRA - PRG
6hKč 1,878–4,826
Mosbach to Prague by bus
Comparing Your Travel Options
The cheapest way to get from Mosbach to Prague is to bus which costs 950 Kč - 1 400 Kč and takes 8h.
The fastest way to get from Mosbach to Prague is to drive which takes 4h 15m and costs 1 700 Kč - 2 600 Kč.
No, there is no direct bus from Mosbach to Prague. However, there are services departing from Mosbach, Bahnhof and arriving at Prague via Neckarsulm station west. The journey, including transfers, takes approximately 8h.
No, there is no direct train from Mosbach to Prague. However, there are services departing from Mosbach, Bahnhof and arriving at Praha Hlavni Nadrazi via Osterburken, Würzburg Hbf, Nürnberg Hbf and Schwandorf. The journey, including transfers, takes approximately 8h 57m.
The distance between Mosbach and Prague is 474 km. The road distance is 452.8 km.
The best way to get from Mosbach to Prague without a car is to bus which takes 8h and costs 950 Kč - 1 400 Kč.
It takes approximately 8h to get from Mosbach to Prague, including transfers.
Mosbach to Prague bus services, operated by FlixBus, depart from Neckarsulm station west.
Mosbach to Prague train services, operated by Arverio Baden-Württemberg, depart from Osterburken station.
The best way to get from Mosbach to Prague is to bus which takes 8h and costs 950 Kč - 1 400 Kč. Alternatively, you can train, which costs 2 500 Kč - 8 000 Kč and takes 8h 57m.
What companies run services between Mosbach, Baden-Württemberg, Germany and Prague, Czechia?
FlixBus operates a bus from Neckarsulm station west to Prague 6 times a week. Tickets cost Kč 950–1,400 and the journey takes 5h 55m. Alternatively, you can take a train from Mosbach, Bahnhof to Praha Hlavni Nadrazi via Osterburken, Wuerzburg Hbf, Würzburg Hbf, Nürnberg Hbf, and Schwandorf in around 8h 57m.
- Website
- lufthansa.com
Flights from Stuttgart Airport to Václav Havel Airport Prague via Munich
- Ave. Duration
- 3h 7m
- When
- Every day
- Estimated price
- Kč 2,100–8,000
Flights from Frankfurt to Václav Havel Airport Prague
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- Kč 1,400–10,000
Flights from Frankfurt to Václav Havel Airport Prague via Munich
- Ave. Duration
- 2h 47m
- When
- Every day
- Estimated price
- Kč 1,400–3,400
- Website
- condor.com
Flights from Frankfurt to Václav Havel Airport Prague
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- Kč 1,300–2,700
- Website
- austrian.com
Flights from Stuttgart Airport to Václav Havel Airport Prague via Vienna
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- Kč 1,900–8,000
- Website
- swiss.com
Flights from Stuttgart Airport to Václav Havel Airport Prague via Zurich
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- Kč 2,000–8,000
- Website
- easyjet.com
Flights from Stuttgart Airport to Václav Havel Airport Prague via Hamburg
- Ave. Duration
- 4h 17m
- When
- Monday
- Estimated price
- Kč 3,300–7,500
- Website
- eurowings.com
Flights from Stuttgart Airport to Václav Havel Airport Prague via Venice
- Ave. Duration
- 3h 35m
- When
- Friday
- Estimated price
- Kč 3,400–6,500
- Website
- airdolomiti.it
Flights from Frankfurt to Václav Havel Airport Prague
- Ave. Duration
- 1h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- Kč 3,200–10,000
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg
Train from Osterburken to Wuerzburg Hbf
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- Kč 340–650
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- Kč 340–410
- 1st Class Ticket
- Kč 440–650
Train from Bad Friedrichshall Hbf to Stuttgart Hbf
- Ave. Duration
- 52 min
- Frequency
- Hourly
- Estimated price
- Kč 290–550
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- Kč 290–350
- 1st Class Ticket
- Kč 390–550
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg GmbH
Train from Osterburken to Wuerzburg Hbf
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- Kč 330–460
- Schedules at
- Arverio Baden-Württemberg GmbH
Train from Bad Friedrichshall Hbf to Stuttgart Hbf
- Ave. Duration
- 52 min
- Frequency
- Hourly
- Estimated price
- Kč 290–410
- Schedules at
- Arverio Baden-Württemberg GmbH
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Osterburken to Wuerzburg Hbf
- Ave. Duration
- 1h 25m
- Frequency
- Every 2 hours
- Estimated price
- Kč 350–1,500
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Würzburg Hbf to Nürnberg Hbf
- Ave. Duration
- 1h 44m
- Frequency
- Hourly
- Estimated price
- Kč 460–1,900
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Nürnberg Hbf to Schwandorf
- Ave. Duration
- 1h 6m
- Frequency
- Hourly
- Estimated price
- Kč 430–1,800
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mosbach, Bahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 16m
- Frequency
- Hourly
- Estimated price
- Kč 330–1,400
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mosbach, Bahnhof to Heidelberg, Hauptbahnhof
- Ave. Duration
- 57 min
- Frequency
- Hourly
- Estimated price
- Kč 250–1,100
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Bad Friedrichshall Hbf to Stuttgart Hbf
- Ave. Duration
- 59 min
- Frequency
- Hourly
- Estimated price
- Kč 280–1,200
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mosbach, Bahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 16m
- Frequency
- Hourly
- Estimated price
- Kč 330–1,400
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Würzburg Hbf to Nürnberg Hbf
- Ave. Duration
- 56 min
- Frequency
- Every 30 minutes
- Estimated price
- Kč 420–950
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- Kč 300–700
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- 0 89 54 888 97 - 25
- [email protected]
- Website
- Die Länderbahn
Train from Schwandorf to Praha Hlavni Nadrazi
- Ave. Duration
- 3h 28m
- Frequency
- Every 4 hours
- Estimated price
- Kč 1,200–2,200
- Schedules at
- Die Länderbahn
- Phone
- _AUSTRIAN_RAILWAYS_(ÖBB)
- Website
- Austrian Railways
Night train from Mannheim Hbf to Praha Hlavni Nadrazi
- Ave. Duration
- 9h 43m
- Frequency
- 3 times a day
- Estimated price
- Kč 3,600–6,000
- Website
- Austrian Railways
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- Kč 190–370
- Website
- Nederlandse Spoorwegen (NS)
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Neckarsulm station west to Prague
- Ave. Duration
- 5h 55m
- Frequency
- 6 times a week
- Estimated price
- Kč 950–1,400
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Heidelberg to Prague - Florenc Main Bus Terminal
- Ave. Duration
- 6h 50m
- Frequency
- Twice daily
- Estimated price
- Kč 900–1,500
- Website
- BlaBlaCar Bus
Want to know more about travelling around Czechia
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Want to know more about Flixbus?
Read the travel guide
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Booking & Getting There
Mosbach to Prague bus services, operated by FlixBus, arrive at Prague station.
Mosbach to Prague train services, operated by Arverio Baden-Württemberg, arrive at Wuerzburg Hbf station.
Yes, the driving distance between Mosbach to Prague is 453 km. It takes approximately 4h 15m to drive from Mosbach to Prague.
Book your Mosbach to Prague train tickets online with Omio.
There are 4580+ hotels available in Prague.


































