There are 6 ways to get from Most to Brno by bus, train, night train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Most to Brnobus 854
4h 40mKč 600–950Bus via Prague
cheapest- Take the bus from Most Budovatelu to Prague Florenc Central Bus Stationbus RegioJet 152101
- Take the bus from Praha, ÚAN Florenc to Brnobus 850 / ...
5h 2mKč 468–921Train
- Take the train from Most to Praha Hlavni Nadrazitrain Re / ...
- Take the train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazitrain Re / ...
5h 24mKč 649–2,193Bus, night train
- Take the bus from Náměstí to Praha-Holešovice Stationbus Arriva Express
- Take the nighttrain from Praha-Holesovice to Brno Hlavni Nadrazinighttrain En
5h 29mKč 679–2,478Drive 298 km
- Drive from Most to Brnocar 298 km
2h 53mKč 1,152–1,664Train via Brno hl.n.
- Take the train from Most to Praha Hlavni Nadrazitrain Re / ...
- Take the train from Praha hl.n. to Brno hl.n.train rj 273 / ...
5h 35mKč 649–1,043
Most to Brno by bus
Comparing Your Travel Options
The cheapest way to get from Most to Brno is to bus via Prague which costs 460 Kč - 950 Kč and takes 5h 2m.
The fastest way to get from Most to Brno is to drive which takes 2h 53m and costs 1 100 Kč - 1 700 Kč.
Yes, there is a direct bus departing from Most and arriving at Brno. Services depart once daily, and operate every day. The journey takes approximately 4h 40m.
No, there is no direct train from Most to Brno. However, there are services departing from Most and arriving at Brno Hlavni Nadrazi via Praha Hlavni Nadrazi. The journey, including transfers, takes approximately 5h 24m.
The distance between Most and Brno is 299 km. The road distance is 298 km.
The best way to get from Most to Brno without a car is to bus which takes 4h 40m and costs 600 Kč - 950 Kč.
The bus from Most to Brno takes 4h 40m including transfers and departs once daily.
Most to Brno bus services, operated by FlixBus, depart from Most station.
Most to Brno train services, operated by České dráhy (ČD), depart from Most station.
The best way to get from Most to Brno is to bus which takes 4h 40m and costs 600 Kč - 950 Kč. Alternatively, you can train, which costs 650 Kč - 2 200 Kč and takes 5h 24m.
What companies run services between Most, Czechia and Brno, Czechia?
FlixBus operates a bus from Most to Brno once daily. Tickets cost Kč 600–950 and the journey takes 4h 40m. Alternatively, you can take a train from Most to Brno Hlavni Nadrazi via Praha Hlavni Nadrazi in around 5h 24m.
- Phone
- +420 221 111 122
- [email protected]
- Website
- Czech Railways (ČD)
Train from Most to Praha Hlavni Nadrazi
- Ave. Duration
- 1h 59m
- Frequency
- Every 3 hours
- Estimated price
- Kč 340–500
- Website
- Czech Railways (ČD)
Train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazi
- Ave. Duration
- 3h 5m
- Frequency
- Hourly
- Estimated price
- Kč 550–850
- Website
- Czech Railways (ČD)
Train from Most to Praha Hlavni Nadrazi
- Ave. Duration
- 1h 59m
- Frequency
- Every 3 hours
- Estimated price
- Kč 340–500
- Website
- Czech Railways (ČD)
- Phone
- +420 222 222 221
- [email protected]
- Website
- RegioJet
Train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazi
- Ave. Duration
- 2h 39m
- Frequency
- Every 3 hours
- Estimated price
- Kč 300–500
- Website
- RegioJet
Train from Praha hl.n. to Brno hl.n.
- Ave. Duration
- 2h 39m
- Frequency
- 4 times a day
- Estimated price
- Kč 300–500
- Website
- RegioJet
- Phone
- +43 (0) 5 1717
- Website
- ÖBB EuroCity
Train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazi
- Ave. Duration
- 2h 38m
- Frequency
- 4 times a day
- Estimated price
- Kč 1,400–1,700
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
- Phone
- +36 (1) 3 49 49 49
- [email protected]
- Website
- Hungarian Railways (MÁV)
Night train from Praha-Holesovice to Brno Hlavni Nadrazi
- Ave. Duration
- 2h 58m
- Frequency
- Once daily
- Estimated price
- Kč 290–340
- Website
- Hungarian Railways (MÁV)
- Phone
- +43 (0) 51717
- Website
- Nightjet
Night train from Praha-Holesovice to Brno Hlavni Nadrazi
- Ave. Duration
- 2h 58m
- Frequency
- Once daily
- Estimated price
- Kč 550–2,300
- Website
- Nightjet
- Sleeper Carriage
- Kč 2,100–2,300
- Couchette Carriage
- Kč 1,300–1,600
- Seating Carriage
- Kč 550–700
.jpg "Nightjet train Innsbruck Hbf")
- Phone
- +421 24 48 58 188
- [email protected]
- Website
- Railways of Slovak Republic (ZSSK)
Train from Praha hl.n. to Brno hl.n.
- Ave. Duration
- 2h 36m
- Frequency
- Every 4 hours
- Estimated price
- Kč 300–550
- Website
- Railways of Slovak Republic (ZSSK)
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Most to Brno
- Ave. Duration
- 4h 40m
- Frequency
- Once daily
- Estimated price
- Kč 600–950
- Website
- Flixbus
Bus from Praha, ÚAN Florenc to Brno
- Ave. Duration
- 2h 55m
- Frequency
- Hourly
- Estimated price
- Kč 460–700
- Website
- Flixbus
- Phone
- +420 725 100 725
- [email protected]
- Website
- arriva.cz
Bus from Náměstí to Praha-Holešovice Station
- Ave. Duration
- 1h 31m
- Frequency
- Every 2 hours
- Estimated price
- Kč 120–180
- Schedules at
- arriva.cz
- Phone
- +420 222 222 221
- [email protected]
- Website
- RegioJet
Bus from Most Budovatelu to Prague Florenc Central Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- Every 3 hours
- Estimated price
- Kč 130–230
- Website
- RegioJet
Bus from Praha, ÚAN Florenc to Brno
- Ave. Duration
- 2h 45m
- Frequency
- Once daily
- Estimated price
- Kč 330–550
- Website
- RegioJet
Want to know more about travelling around Czechia
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Related travel guides
Want to know more about Flixbus?
Read the travel guide
Booking & Getting There
Most to Brno bus services, operated by FlixBus, arrive at Brno station.
Most to Brno train services, operated by České dráhy (ČD), arrive at Praha Hlavni Nadrazi station.
Yes, the driving distance between Most to Brno is 298 km. It takes approximately 2h 53m to drive from Most to Brno.
Book your Most to Brno train tickets online with Omio.
Book your Most to Brno bus tickets online with Omio and FlixBus.
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