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How to get fromMount Pleasant to La Crosseby train (Amtrak), train, bus, car, plane, or bus (Greyhound)

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There are 5 ways to get from Mount Pleasant to La Crosse by train (Amtrak), train, bus, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Mt. Pleasant Station to Chicago Union Stationtrain train California Zephyr
    2. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train Empire Builder / ...
    10h 43m
    $158–343

  2. Drive 227 mi

    cheapest
    1. Drive from Mount Pleasant to La Crossecar car 227 mi
    4h 32m
    $42–60

  3. Train, bus

    1. Take the train from Mt. Pleasant Station to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to La Crossebus bus
    12h 42m
    $133–263

  4. Drive, fly

    1. Drive from Mount Pleasant to Cedar-Rapids-Airport-CIDcar car
    2. Fly from The Eastern Iowa Airport (CID) to La Crosse (LSE)plane plane CID - LSE
    6h 45m
    $132–691

  5. Bus

    1. Take the bus from Mount Pleasant to Des Moinesbus bus
    2. Take the bus from Des Moines to Saint Paul Union Depotbus bus
    3. Take the bus from St. Paul to La Crossebus bus
    15h 14m
    $115–208

Mount Pleasant to La Crosse by train (Amtrak)

Calendar7Weekly Trains
Duration10h 43mAverage Duration
Ticket$158Cheapest Price
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Questions & Answers

Map of how to get from Mount Pleasant to La Crosse.ExpandLaunch map view
  • Distance: 512.6 mi
  • Duration: 10h 43m

What companies run services between Mount Pleasant, IA, USA and La Crosse, WI, USA?

You can take a train from Mt. Pleasant Station to La Crosse Amtrak Station via Chicago Union Station in around 10h 43m. Alternatively, you can take a vehicle from Mount Pleasant to La Crosse via Mount Pleasant, Des Moines, and St. Paul in around 15h 14m.

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