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How to get fromMount Pleasant to Chicagoby bus, plane, train (Amtrak), car, taxi, or train

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There are 7 ways to get from Mount Pleasant to Chicago by bus, plane, train (Amtrak), car, taxi, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 41 bus, bus to Charleston International Airport, fly to Chicago Midway International Airport

    best
    1. Take the bus from Coleman Blvd / Chuck Dawley Blvd to Transit Mallbus bus
    2. Take the bus from Calhoun St / Jonathan Lucas St to Fuel Farm Rd / Dreamliner Drbus bus
    3. Fly from Charleston International Airport (CHS) to Chicago Midway International Airport (MDW)plane plane CHS - MDW
    6h 8m

  2. Drive to Hilton Head Airport, fly to Chicago O'Hare International Airport

    cheapest
    1. Drive from Mount Pleasant to Hilton Head Airport (HHH)car car
    2. Fly from Hilton Head Airport (HHH) to Chicago O'Hare International Airport (ORD)plane plane HHH - ORD
    5h 51m
    $80–351

  3. Train (Amtrak)

    1. Take the train from Charleston Amtrak Station to Petersburg Amtrak Stationtrain train Silver Meteor / ...
    2. Take the train from Petersburg Amtrak Station to Chicago Union Stationtrain train Floridian
    29h 14m
    $730–1,157

  4. Drive, bus, taxi, train

    1. Drive from Mount Pleasant to Sonic at Walmartcar car
    2. Take the bus from Sonic at Walmart to Bluffton Transfer Centerbus bus 302
    3. Take the taxi from Bluffton Transfer Center to Savannah Stationtaxi taxi
    4. Take the train from Savannah Station to Fayetteville Amtrak Stationtrain train
    5. Take the bus from Fayetteville Bus Station to Washington Union Stationbus bus
    6. Take the bus from Washington Union Station to Chicago Bus Stationbus bus
    34h 29m

  5. Drive  876.4 mi

    1. Drive from Mount Pleasant to Chicagocar car 876.4 mi
    16h 2m
    $150–217

  6. Line 41 bus, bus to Charleston International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Coleman Blvd / Chuck Dawley Blvd to Transit Mallbus bus
    2. Take the bus from Calhoun St / Jonathan Lucas St to Fuel Farm Rd / Dreamliner Drbus bus
    3. Fly from Charleston International Airport (CHS) to Chicago O'Hare International Airport (ORD)plane plane CHS - ORD
    6h 34m

  7. Drive to Charlotte Douglas International Airport, fly to South Bend, train

    1. Drive from Mount Pleasant to Charlotte-Airport-CLTcar car
    2. Fly from Charlotte Douglas International Airport (CLT) to South Bend (SBN)plane plane CLT - SBN
    3. Take the train from South Bend Airport to Van Buren St.train train
    8h 22m
    $120–479

Charleston International Airport (CHS) to Chicago Midway International Airport (MDW) flights

Calendar36Weekly Planes
Duration4h 16mAverage Duration
Ticket$95Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mount Pleasant to Chicago.ExpandLaunch map view
  • Distance: 778.8 mi
  • Duration: 6h 8m

What companies run services between Mount Pleasant, SC, USA and Chicago, IL, USA?

You can take a vehicle from Mount Pleasant to Chicago Union Station via Charleston Amtrak Station and Petersburg Amtrak Station in around 29h 14m.

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