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How to get fromMount Pleasant to Duke Universityby train (Amtrak), bus, car, plane, or train

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There are 6 ways to get from Mount Pleasant to Duke University by train (Amtrak), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Charleston Amtrak Station to Selma Stationtrain train Palmetto
    2. Take the train from Selma Station to Durham Amtrak Stationtrain train Carolinian
    7h 12m
    $130–240

  2. Drive 254.9 mi

    cheapest
    1. Drive from Mount Pleasant to Duke Universitycar car 254.9 mi
    5h 39m
    $47–68

  3. Bus, drive

    1. Take the bus from Stuart Engals Blvd / Wando Crossing Center to S. Pinckney St / Society Rdbus bus
    2. Drive from S. Pinckney St / Society Rd to Myrtle Beach Bus Stationcar car
    3. Take the bus from Myrtle Beach Bus Station to Raleigh Bus Stationbus bus
    15h 56m
    $80–166

  4. Fly Charleston International Airport to Raleigh-Durham International Airport

    1. Fly from Charleston International Airport (CHS) to Raleigh-Durham International Airport (RDU)plane plane CHS - RDU
    8h 1m
    $260–610

  5. Drive to Hilton Head Airport, fly to Raleigh-Durham International Airport

    1. Drive from Mount Pleasant to Hilton Head Airport (HHH)car car
    2. Fly from Hilton Head Airport (HHH) to Raleigh-Durham International Airport (RDU)plane plane HHH - RDU
    8h
    $82–385

  6. Fly Charleston International Airport to Piedmont Triad International Airport, train

    1. Fly from Charleston International Airport (CHS) to Piedmont Triad International Airport (GSO)plane plane CHS - GSO
    2. Take the train from Greensboro to Durham Amtrak Stationtrain train
    8h 48m
    $360–1,379

Charleston International Airport (CHS) to Raleigh-Durham International Airport (RDU) flights

Calendar126Weekly Planes
Duration3h 53mAverage Duration
Ticket$55Cheapest Price
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Questions & Answers

Map of how to get from Mount Pleasant to Duke University.ExpandLaunch map view
  • Distance: 294.6 mi
  • Duration: 7h 12m

What companies run services between Mount Pleasant, SC, USA and Duke University, NC, USA?

You can take a vehicle from Mount Pleasant to Duke University via Charleston Amtrak Station, Selma Station, Durham Amtrak Station, Durham Station, and Trent Dr at Erwin Rd in around 7h 12m. Alternatively, American Airlines, Delta, and two other airlines fly from Charleston International Airport (CHS) to Raleigh-Durham International Airport (RDU) hourly.

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