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How to get fromMount Pleasant to Fort Myersby bus, plane, car, taxi, or train

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There are 8 ways to get from Mount Pleasant to Fort Myers by bus, plane, car, taxi, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly to Ft. Myers, line 140 bus

    best
    1. Take the bus from Stuart Engals Blvd / Wando Crossing Shopping Center to Calhoun St / Jonathan Lucas Stbus bus
    2. Take the bus from Calhoun St / Jonathan Lucas St to Fuel Farm Rd / Dreamliner Drbus bus
    3. Fly from Charleston International Airport (CHS) to Ft. Myers (RSW)plane plane CHS - RSW
    4. Take the bus from South Fort Myers Transfer/P&R to Edison Mall Transfer Ctrbus bus
    6h 28m

  2. Drive 534.9 mi

    cheapest
    1. Drive from Mount Pleasant to Fort Myerscar car 534.9 mi
    9h 42m
    $98–141

  3. Drive, bus, taxi, train

    1. Drive from Mount Pleasant to Sonic at Walmartcar car
    2. Take the bus from Sonic at Walmart to Bluffton Transfer Centerbus bus 302
    3. Take the taxi from Bluffton Transfer Center to Savannah Stationtaxi taxi
    4. Take the train from Savannah Station to Tampatrain train
    5. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    16h 39m

  4. Drive, bus, taxi, train via Jacksonville

    1. Drive from Mount Pleasant to Sonic at Walmartcar car
    2. Take the bus from Sonic at Walmart to Bluffton Transfer Centerbus bus 302
    3. Take the taxi from Bluffton Transfer Center to Savannah Stationtaxi taxi
    4. Take the train from Savannah Station to Jacksonvilletrain train
    5. Take the bus from Jacksonville to Wildwood Amtrak Stationbus bus
    6. Take the bus from Wildwood to Fort Myersbus bus
    16h 47m

  5. Fly to Fort Lauderdale–Hollywood International Airport, bus

    1. Fly from Charleston International Airport (CHS) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane CHS - FLL
    2. Take the bus from Fort Lauderdale International Airport to Fort Myers Bus Stopbus bus
    8h 3m
    $194–1,138

  6. Fly to Tampa, bus

    1. Fly from Charleston International Airport (CHS) to Tampa (TPA)plane plane CHS - TPA
    2. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    9h 33m
    $166–380

  7. Fly to Miami International Airport, bus

    1. Fly from Charleston International Airport (CHS) to Miami International Airport (MIA)plane plane CHS - MIA
    2. Take the bus from Miami Airport Station to Fort Myers Bus Stopbus bus
    9h 2m
    $528–1,048

  8. Train, bus

    1. Take the train from Charleston Amtrak Station to Fort Lauderdale Amtrak Stationtrain train Silver Meteor
    2. Take the bus from Fort Lauderdale International Airport to Fort Myers Bus Stopbus bus FlixBus 2421
    17h 47m
    $262–507

Charleston International Airport (CHS) to Ft. Myers (RSW) flights

Calendar23Weekly Planes
Duration3h 2mAverage Duration
Ticket$87Cheapest Price
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Questions & Answers

Map of how to get from Mount Pleasant to Fort Myers.ExpandLaunch map view
  • Distance: 486.1 mi
  • Duration: 6h 28m

What companies run services between Mount Pleasant, SC, USA and Fort Myers, FL, USA?

There is no direct connection from Mount Pleasant to Fort Myers. However, you can take the bus to Calhoun St / Jonathan Lucas St, take the bus to Fuel Farm Rd / Dreamliner Dr, walk to Charleston-Airport-CHS airport, fly to Ft. Myers (RSW), walk to Rsw, take the line 50 bus to South Fort Myers Transfer/P&R, then take the line 140 bus to Edison Mall Transfer Ctr. Alternatively, you can drive to Sonic at Walmart, take the bus to Bluffton Transfer Center, take the taxi to Savannah Station, take the train to Tampa, walk to Nebraska Ave @ Twiggs St, take the line 400 bus to Marion Transit Center, walk to Tampa Bus Station, then take the bus to Fort Myers Bus Stop.

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