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How to get fromMount Pleasant to Panama City Beachby plane, train, bus, car, or taxi

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There are 9 ways to get from Mount Pleasant to Panama City Beach by plane, train, bus, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Charleston International Airport to Northwest Florida Beaches International Airport

    best
    1. Fly from Charleston International Airport (CHS) to Northwest Florida Beaches International Airport (ECP)plane plane CHS - ECP
    6h 37m
    $113–418

  2. Fly Charleston International Airport to Destin–Fort Walton Beach Airport, drive

    cheapest
    1. Fly from Charleston International Airport (CHS) to Destin–Fort Walton Beach Airport (VPS)plane plane CHS - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar car
    7h 27m
    $73–369

  3. Train, bus via Tallahassee

    1. Take the train from Charleston Amtrak Station to Jacksonvilletrain train
    2. Take the bus from Jacksonville to Tallahasseebus bus
    3. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    13h 4m
    $164–312

  4. Drive 451.9 mi

    1. Drive from Mount Pleasant to Panama City Beachcar car 451.9 mi
    9h 10m
    $83–120

  5. Drive to Hilton Head Airport, fly to Northwest Florida Beaches International Airport

    1. Drive from Mount Pleasant to Hilton Head Airport (HHH)car car
    2. Fly from Hilton Head Airport (HHH) to Northwest Florida Beaches International Airport (ECP)plane plane HHH - ECP
    7h
    $130–433

  6. Fly Charleston International Airport to Dothan Regional Airport, drive

    1. Fly from Charleston International Airport (CHS) to Dothan Regional Airport (DHN)plane plane CHS - DHN
    2. Drive from Dothan Regional Airport (DHN) to Panama City Beachcar car
    8h 9m
    $75–359

  7. Fly Charleston International Airport to Pensacola International Airport, bus

    1. Fly from Charleston International Airport (CHS) to Pensacola International Airport (PNS)plane plane CHS - PNS
    2. Take the bus from Pensacola Airport to Panama City Beach Bus Stationbus bus
    9h 34m
    $386–1,243

  8. Drive, bus, taxi, train

    1. Drive from Mount Pleasant to Sonic at Walmartcar car
    2. Take the bus from Sonic at Walmart to Bluffton Transfer Centerbus bus 302
    3. Take the taxi from Bluffton Transfer Center to Savannah Stationtaxi taxi
    4. Take the train from Savannah Station to Jacksonvilletrain train
    5. Take the bus from Jacksonville to Tallahasseebus bus
    6. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    14h 42m

  9. Train, bus

    1. Take the train from Charleston Amtrak Station to Jacksonvilletrain train Silver Meteor
    2. Take the bus from Jacksonville to Panama City Beach Bus Stationbus bus Greyhound US0760S
    16h 36m
    $131–271

Charleston International Airport (CHS) to Northwest Florida Beaches International Airport (ECP) flights

Calendar66Weekly Planes
Duration4h 46mAverage Duration
Ticket$61Cheapest Price
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Questions & Answers

Map of how to get from Mount Pleasant to Panama City Beach.ExpandLaunch map view
  • Distance: 420.4 mi
  • Duration: 6h 37m

What companies run services between Mount Pleasant, SC, USA and Panama City Beach, FL, USA?

Delta, Southwest Airlines, and American Airlines fly from Charleston International Airport (CHS) to Northwest Florida Beaches International Airport (ECP) every 3 hours.

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