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How to get fromMount Pleasant to Winston-Salemby train, bus, car, plane, or bus (Greyhound)

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There are 7 ways to get from Mount Pleasant to Winston-Salem by train, bus, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Charleston Amtrak Station to Selma Stationtrain train
    2. Take the train from Selma Station to Greensborotrain train
    3. Take the bus from Greensboro Bus Stop to Winston Salem(Trans Center)bus bus
    9h 15m
    $149–280

  2. Drive 285.6 mi

    cheapest
    1. Drive from Mount Pleasant to Winston-Salemcar car 285.6 mi
    4h 58m
    $53–76

  3. Train, bus via Fayetteville

    1. Take the train from Charleston Amtrak Station to Fayetteville Amtrak Stationtrain train Palmetto / ...
    2. Take the bus from Fayetteville Bus Station to Winston Salem(Trans Center)bus bus Greyhound US0647S
    11h 19m
    $84–161

  4. Fly Charleston International Airport to Piedmont Triad International Airport

    1. Fly from Charleston International Airport (CHS) to Piedmont Triad International Airport (GSO)plane plane CHS - GSO
    7h
    $332–1,326

  5. Bus

    1. Take the bus from Charleston Bus Station to Charlotte Bus Stationbus bus Greyhound US0643S
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus Greyhound US0670
    12h 10m
    $53–131

  6. Fly Charleston International Airport to Charlotte Douglas International Airport, bus

    1. Fly from Charleston International Airport (CHS) to Charlotte Douglas International Airport (CLT)plane plane CHS - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    7h 9m
    $69–459

  7. Drive to Hilton Head Airport, fly to Charlotte Douglas International Airport, bus

    1. Drive from Mount Pleasant to Hilton Head Airport (HHH)car car
    2. Fly from Hilton Head Airport (HHH) to Charlotte Douglas International Airport (CLT)plane plane HHH - CLT
    3. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    6h 54m
    $91–504

Mount Pleasant to Winston-Salem by bus and train

Calendar14Weekly Services
Duration11h 19mAverage Duration
Ticket$84Cheapest Price
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Questions & Answers

Map of how to get from Mount Pleasant to Winston-Salem.ExpandLaunch map view
  • Distance: 373.4 mi
  • Duration: 9h 15m

What companies run services between Mount Pleasant, SC, USA and Winston-Salem, NC, USA?

American Airlines, Delta, and United Airlines fly from Charleston International Airport (CHS) to Piedmont Triad International Airport (GSO) hourly. Alternatively, you can take a bus from Houston Northcutt Blvd / Harbor Pointe Dr to Winston Salem(Trans Center) via Mary St / Meeting St, N. Charleston SuperStop, North Charleston Transit Center, Charleston Bus Station, and Charlotte Bus Station in around 12h 10m.

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