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How to get fromMount Prospect to Louisvilleby train, plane, bus (Greyhound, Flixbus), bus, car, or bus (Amtrak)

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There are 8 ways to get from Mount Prospect to Louisville by train, plane, bus (Greyhound, Flixbus), bus, car, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Chicago O'Hare International Airport, fly to Louisville International Airport

    best
    1. Take the train from Mt. Prospect to Irving Parktrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    4h 33m
    $72–453

  2. Bus

    cheapest
    1. Take the bus from Chicago Bus Station to Louisville Bus Stationbus bus Greyhound US0100
    8h 1m
    $47–103

  3. Train, bus via Indianapolis

    1. Take the train from Chicago Union Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus Greyhound US0100 / ...
    9h 34m
    $79–173

  4. Drive  314.8 mi

    1. Drive from Mount Prospect to Louisvillecar car 314.8 mi
    5h 33m
    $58–83

  5. Fly Chicago O'Hare International Airport to Blue Grass Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane plane ORD - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    4h 44m
    $59–319

  6. Train to Chicago Midway International Airport, fly to Louisville International Airport

    1. Take the train from Mt. Prospect to Chicago OTCtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    5h 6m
    $92–613

  7. Train, bus

    1. Take the train from Millennium Station to Gary Metro Centertrain train Ssl / ...
    2. Take the bus from Gary Bus Station to Louisville Bus Stationbus bus Greyhound US0100
    8h 26m
    $54–102

  8. Bus via Lafayette (Amtrak)

    1. Take the bus from Chicago Union Station to Lafayette Amtrak Stationbus bus Chicago
    2. Take the bus from Lafayette Amtrak Station to Louisville, KYbus bus Chicago
    10h 10m
    $60–103

Mount Prospect to Louisville by train and bus

Calendar40Weekly Services
Duration8h 1mAverage Duration
Ticket$47Cheapest Price
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Questions & Answers

Map of how to get from Mount Prospect to Louisville.ExpandLaunch map view
  • Distance: 315.1 mi
  • Duration: 4h 33m

What companies run services between Mount Prospect, IL, USA and Louisville, KY, USA?

Greyhound USA operates a bus from Chicago Bus Station to Louisville Bus Station 4 times a day. Tickets cost $45–95 and the journey takes 6h 5m. Flixbus USA also services this route twice daily.

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