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How to get fromMount Prospect to Louisvilleby train, plane, bus (Greyhound, Amtrak), bus, car, or bus (Amtrak)

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There are 8 ways to get from Mount Prospect to Louisville by train, plane, bus (Greyhound, Amtrak), bus, car, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Chicago O'Hare International Airport, fly to Louisville International Airport

    best
    1. Take the train from Mt. Prospect to Irving Parktrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    4h 35m
    $72–443

  2. Bus via Indianapolis

    cheapest
    1. Take the bus from Chicago Bus Station to Indianapolis Union Stationbus bus Greyhound US0100 / ...
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    8h 26m
    $55–103

  3. Train, bus (Amtrak)

    1. Take the train from Chicago Union Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    10h 9m
    $84–183

  4. Drive 314.7 mi

    1. Drive from Mount Prospect to Louisvillecar car 314.7 mi
    5h 32m
    $58–83

  5. Fly Chicago O'Hare International Airport to Blue Grass Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane plane ORD - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    4h 44m
    $64–329

  6. Train to Chicago Midway International Airport, fly to Louisville International Airport

    1. Take the train from Mt. Prospect to Chicago OTCtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    5h 6m
    $87–563

  7. Fly Chicago O'Hare International Airport to Evansville, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Evansville (EVV)plane plane ORD - EVV
    2. Take the bus from Evansville, IN to Louisville, KYbus bus
    6h 43m
    $101–455

  8. Bus (Amtrak)

    1. Take the bus from Chicago Union Station to Louisville, KYbus bus Chicago
    8h 50m
    $57–68

Mount Prospect to Louisville by train and bus

Calendar14Weekly Services
Duration8h 26mAverage Duration
Ticket$55Cheapest Price
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Questions & Answers

Map of how to get from Mount Prospect to Louisville.ExpandLaunch map view
  • Distance: 315.1 mi
  • Duration: 4h 35m

What companies run services between Mount Prospect, IL, USA and Louisville, KY, USA?

You can take a train from Mt. Prospect to Louisville, KY via Chicago OTC, Madison & Canal, Harrison & Jefferson, Chicago Bus Station, and Indianapolis Union Station in around 8h 26m.

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Train operators
Bus operators

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