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How to get fromMount Vernon to Des Moinesby bus (Greyhound), car, bus, or plane

Find Transport to Des Moines

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There are 4 ways to get from Mount Vernon to Des Moines by bus (Greyhound), car, bus, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Mount Vernon to St Louis Bus Stationbus bus Greyhound US0185 / ...
    2. Take the bus from St Louis Bus Station to Des Moinesbus bus Greyhound US0153S
    11h
    $80–153

  2. Drive 408.6 mi

    cheapest
    1. Drive from Mount Vernon to Des Moinescar car 408.6 mi
    7h 55m
    $75–108

  3. Bus to Williamson County Regional Airport, fly

    1. Take the bus from El Rancherito - Mount Vernon to Marathon Gas Station - Marionbus bus
    2. Fly from Williamson County Regional Airport (MWA) to Des Moines (DSM)plane plane MWA - DSM
    6h 37m
    $199–921

  4. Bus to Lambert–St. Louis International Airport, fly

    1. Take the bus from Mount Vernon to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Des Moines (DSM)plane plane STL - DSM
    6h 45m
    $180–857

Williamson County Regional Airport (MWA) to Des Moines (DSM) flights

Calendar32Weekly Planes
Duration6h 56mAverage Duration
Ticket$133Cheapest Price
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Questions & Answers

Map of how to get from Mount Vernon to Des Moines.ExpandLaunch map view
  • Distance: 496.7 mi
  • Duration: 11h

What companies run services between Mount Vernon, IL, USA and Des Moines, IA, USA?

You can take a vehicle from Mount Vernon to Des Moines via Mount Vernon and St Louis Bus Station in around 11h.

Airlines
Bus operators

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