There are 10 ways to get from Mulhouse to San Sebastián de los Reyes by plane, train (TGV, Renfe, Ouigo), bus, car, train, or train (TGV, Renfe)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Basel
best- Fly from Basel (BSL) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane BSL - MAD
6h 3m€74–255Train via Barcelona
- Take the train from Mulhouse Ville to Lyon Part Dieutrain Tgv
- Take the train from Lyon Part Dieu to Barcelona-Santstrain
- Take the train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandestrain Ave
12h 48m€197–393Bus via Lyon
- Take the bus from Mulhouse to Lyon Saint-Exupéry Airportbus N1759 / ...
- Take the bus from Lyon to Madridbus FlixBus N748 / ...
25h 1m€148–229Drive 1,471.3 km
- Drive from Mulhouse to San Sebastián de los Reyescar 1,471.3 km
14h 30m€279–402Train to Zurich Airport, fly
- Take the train from Basel SBB to Zürich HBtrain
- Fly from Zurich Airport (ZRH) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane ZRH - MAD
7h 29m€111–336Train to Strasbourg International Airport, fly
- Take the train from Mulhouse Ville to Strasbourgtrain
- Fly from Strasbourg International Airport (SXB) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane SXB - MAD
6h 26m€104–321Train to Luxembourg, fly
- Take the train from Mulhouse Ville to Luxembourgtrain
- Fly from Luxembourg (LUX) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane LUX - MAD
8h 22m€131–399Train, train to Geneva International Airport, fly
- Take the train from Basel SBB to Renens VDtrain
- Take the train from Renens VD to Genève-Aéroporttrain
- Fly from Geneva International Airport (GVA) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane GVA - MAD
9h 19m€129–377Train
- Take the train from Mulhouse Ville to Avignon Tgvtrain Tgv
- Take the train from Avignon Tgv to Madrid-Puerta de Atocha-Almudena Grandestrain 9730
13h 48m€251–381Bus
- Take the bus from Mulhouse to Strasbourgbus FlixBus 108 / ...
- Take the bus from Strasbourg - L'Étoile Park Bus Station to Madrid - Barajas Airport T4bus BlaBlaCar Bus
27h 16m€150–257
Mulhouse to San Sebastián de los Reyes by train
Comparing Your Travel Options
The cheapest way to get from Mulhouse to San Sebastián de los Reyes is to fly which costs €70 - €260 and takes 6h 3m.
The fastest way to get from Mulhouse to San Sebastián de los Reyes is to fly which takes 6h 3m and costs €70 - €260.
No, there is no direct bus from Mulhouse to San Sebastián de los Reyes. However, there are services departing from Mulhouse and arriving at Estación De Atocha via Lyon - St. Exupéry Airport T1 Bus Stop, Lyon and Méndez Álvaro. The journey, including transfers, takes approximately 25h 1m.
No, there is no direct train from Mulhouse to San Sebastián de los Reyes. However, there are services departing from Mulhouse Ville and arriving at Alcobendas-San Sebastián de los Reyes via Lyon Part Dieu, Barcelona-Sants and Madrid-Atocha Cercanías. The journey, including transfers, takes approximately 12h 48m.
The distance between Mulhouse and San Sebastián de los Reyes is 1244 km. The road distance is 1471.3 km.
The best way to get from Mulhouse to San Sebastián de los Reyes without a car is to train via Barcelona which takes 12h 48m and costs €190 - €400.
It takes approximately 6h 3m to get from Mulhouse to San Sebastián de los Reyes, including transfers.
Mulhouse to San Sebastián de los Reyes bus services, operated by FlixBus, depart from Mulhouse station.
Mulhouse to San Sebastián de los Reyes train services, operated by TGV inOui, depart from Mulhouse Ville station.
The best way to get from Mulhouse to San Sebastián de los Reyes is to fly which takes 6h 3m and costs €70 - €260. Alternatively, you can train via Barcelona, which costs €190 - €400 and takes 12h 48m, you could also bus via Lyon, which costs €140 - €230 and takes 25h 1m.
What companies run services between Mulhouse, France and San Sebastián de los Reyes, Spain?
easyJet, Vueling Airlines, and Iberia fly from Basel (BSL) to Adolfo Suárez Madrid–Barajas Airport (MAD) 3 times a day. Alternatively, you can take a train from Mulhouse Ville to Alcobendas-San Sebastián de los Reyes via Lyon Part Dieu, Barcelona-Sants, Madrid-Puerta De Atocha-Almudena Grandes, and Madrid-Atocha Cercanías in around 12h 48m.
- Website
- iberia.com
Flights from Basel to Adolfo Suárez Madrid–Barajas Airport via Barcelona
- Ave. Duration
- 5h 5m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- €50–250
Flights from Zurich Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- €65–190
Flights from Strasbourg International Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 20m
- When
- Monday to Friday
- Estimated price
- €100–470
Flights from Strasbourg International Airport to Adolfo Suárez Madrid–Barajas Airport via Barcelona
- Ave. Duration
- 5h 35m
- When
- Monday and Thursday
- Estimated price
- €80–240
Flights from Geneva International Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- €55–160
Flights from Geneva International Airport to Adolfo Suárez Madrid–Barajas Airport via Barcelona
- Ave. Duration
- 3h 50m
- When
- Sunday
- Estimated price
- €65–460
- Website
- vueling.com
Flights from Basel to Adolfo Suárez Madrid–Barajas Airport via Barcelona
- Ave. Duration
- 5h 5m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- €50–250
Flights from Zurich Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- €65–190
Flights from Strasbourg International Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 20m
- When
- Monday to Friday
- Estimated price
- €100–470
Flights from Strasbourg International Airport to Adolfo Suárez Madrid–Barajas Airport via Barcelona
- Ave. Duration
- 5h 35m
- When
- Monday and Thursday
- Estimated price
- €80–240
Flights from Geneva International Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- €55–160
Flights from Geneva International Airport to Adolfo Suárez Madrid–Barajas Airport via Barcelona
- Ave. Duration
- 3h 50m
- When
- Sunday
- Estimated price
- €65–460
- Website
- ryanair.com
Flights from Luxembourg to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 30m
- When
- Friday, Saturday, Sunday, Monday, and Thursday
- Estimated price
- €50–260
- Website
- easyjet.com
Flights from Basel to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 26m
- When
- Every day
- Estimated price
- €50–220
Flights from Geneva International Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 10m
- When
- Monday, Friday, and Sunday
- Estimated price
- €35–210
- Website
- aireuropa.com
Flights from Zurich Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- €55–200
Flights from Geneva International Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 1h 57m
- When
- Every day
- Estimated price
- €45–200
- Website
- swiss.com
Flights from Zurich Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- €75–230
- Website
- luxair.lu
Flights from Luxembourg to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 22m
- When
- Monday, Friday, Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- €75–240
- Website
- airfrance.com
Flights from Luxembourg to Adolfo Suárez Madrid–Barajas Airport via Paris Charles de Gaulle
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- €65–350
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Mulhouse Ville to Lyon Part Dieu
- Ave. Duration
- 3h 7m
- Frequency
- Every 4 hours
- Estimated price
- €80–120
- Website
- TGV inOui
Train from Mulhouse Ville to Strasbourg
- Ave. Duration
- 1h 1m
- Frequency
- Every 2 hours
- Estimated price
- €22–35
- Website
- TGV inOui
Train from Mulhouse Ville to Luxembourg
- Ave. Duration
- 2h 37m
- Frequency
- 4 times a day
- Estimated price
- €60–95
- Website
- TGV inOui
Train from Mulhouse Ville to Avignon Tgv
- Ave. Duration
- 4h 27m
- Frequency
- 3 times a day
- Estimated price
- €120–190
- Website
- TGV inOui
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact Details
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Mulhouse Ville to Lyon Part Dieu
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- €75–120
- Website
- Oui.SNCF
Train from Mulhouse Ville to Strasbourg
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €20–35
- Website
- Oui.SNCF
Train from Mulhouse Ville to Avignon Tgv
- Ave. Duration
- 4h 32m
- Frequency
- Twice daily
- Estimated price
- €120–190
- Website
- Oui.SNCF
Rome2Rio's guide to Renfe Viajeros
Contact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Lyon Part Dieu to Barcelona-Sants
- Ave. Duration
- 4h 48m
- Frequency
- Twice daily
- Estimated price
- €80–120
- Website
- Renfe Viajeros
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 3h 28m
- Frequency
- 4 times a day
- Estimated price
- €75–110
- Website
- Renfe Viajeros
Train from Avignon Tgv to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 7h 37m
- Frequency
- Twice daily
- Estimated price
- €130–190
- Website
- Renfe Viajeros
Rome2Rio's guide to Renfe AVE
Contact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe AVE
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 3h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €80–150
- Website
- Renfe AVE
- Phone
- +34 900 926 851
- [email protected]
- Website
- Iryo
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 3h 24m
- Frequency
- Hourly
- Estimated price
- €50–100
- Website
- Iryo
- Phone
- +34 900 759 781
- Website
- Ouigo
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 3h 28m
- Frequency
- Hourly
- Estimated price
- €40–75
- Website
- Ouigo
Train from Basel SBB to Zürich HB
- Ave. Duration
- 1h 13m
- Frequency
- Every 20 minutes
- Estimated price
- €29–45
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Basel SBB to Renens VD
- Ave. Duration
- 2h 16m
- Frequency
- Hourly
- Estimated price
- €55–90
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Renens VD to Genève-Aéroport
- Ave. Duration
- 44 min
- Frequency
- Every 20 minutes
- Estimated price
- €20–35
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Mulhouse to Lyon Saint-Exupéry Airport
- Ave. Duration
- 5h 35m
- Frequency
- Once daily
- Estimated price
- €30–50
- Website
- Flixbus
Bus from Lyon to Madrid
- Ave. Duration
- 16h 40m
- Frequency
- Twice daily
- Estimated price
- €110–170
- Website
- Flixbus
Bus from Mulhouse to Strasbourg
- Ave. Duration
- 1h 35m
- Frequency
- Every 4 hours
- Estimated price
- €10–16
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Mulhouse to Strasbourg
- Ave. Duration
- 1h 45m
- Frequency
- 5 times a day
- Estimated price
- €9–15
- Website
- BlaBlaCar Bus
Bus from Strasbourg - L'Étoile Park Bus Station to Madrid - Barajas Airport T4
- Ave. Duration
- 24h 20m
- Frequency
- Once daily
- Estimated price
- €140–240
- Website
- BlaBlaCar Bus
Want to know more about travelling around Spain
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Booking & Getting There
Mulhouse to San Sebastián de los Reyes bus services, operated by FlixBus, arrive at Lyon Saint-Exupéry Airport station.
Mulhouse to San Sebastián de los Reyes train services, operated by TGV inOui, arrive at Lyon Part Dieu station.
Yes, the driving distance between Mulhouse to San Sebastián de los Reyes is 1471 km. It takes approximately 14h 30m to drive from Mulhouse to San Sebastián de los Reyes.
Book your Mulhouse to San Sebastián de los Reyes train tickets online with Omio.
Book your Mulhouse to San Sebastián de los Reyes bus tickets online with Omio.
There are 7043+ hotels available in San Sebastián de los Reyes.

































