There are 8 ways to get from Mulhouse to Siena by bus, train (Trenitalia), car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Basel to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Sienabus N528 / ...
9h 25mBus via Milan
cheapest- Take the bus from Mulhouse to Milanbus FlixBus N473
- Take the bus from Milano, Autostazione Lampugnano to Sienabus N528 / ...
11h 5m€61–106Train
- Take the train from Basel SBB to Luganotrain Ec
- Take the train from Lugano to Milano Centraletrain
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
10h 33m€95–512Drive 733 km
- Drive from Mulhouse to Sienacar 733 km
7h 36m€115–166Train to Zurich Airport, fly to Florence Peretola Airport, train
- Take the train from Mulhouse Ville to Zuerich Hbtrain
- Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane ZRH - FLR
- Take the train from Firenze S.M.N. to Sienatrain
7h 11m€142–313Fly Basel to Florence Peretola Airport, train
- Fly from Basel (BSL) to Florence Peretola Airport (FLR)plane BSL - FLR
- Take the train from Firenze S.M.N. to Sienatrain
8h 15m€118–280Train to Zurich Airport, fly to Bologna Guglielmo Marconi Airport, train
- Take the train from Mulhouse Ville to Zuerich Hbtrain
- Fly from Zurich Airport (ZRH) to Bologna Guglielmo Marconi Airport (BLQ)plane ZRH - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
7h 27m€134–318Train to Zurich Airport, fly to Venice Marco Polo Airport, train
- Take the train from Mulhouse Ville to Zuerich Hbtrain
- Fly from Zurich Airport (ZRH) to Venice Marco Polo Airport (VCE)plane ZRH - VCE
- Take the train from Venezia Mestre to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
9h 30m€151–378
Mulhouse to Siena by train
Questions & Answers
The cheapest way to get from Mulhouse to Siena is to bus via Milan which costs €60 - €110 and takes 11h 5m.
The fastest way to get from Mulhouse to Siena is to train and fly which takes 7h 11m and costs €140 - €320.
No, there is no direct bus from Mulhouse to Siena. However, there are services departing from Mulhouse and arriving at Siena via Basel EuroAirport, Ankunft, Basel and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 9h 25m.
No, there is no direct train from Mulhouse to Siena. However, there are services departing from Mulhouse Ville and arriving at Siena via Basel SBB, Lugano, Milano Centrale and Firenze S.M.N.. The journey, including transfers, takes approximately 10h 33m.
The distance between Mulhouse and Siena is 818 km. The road distance is 733 km.
The best way to get from Mulhouse to Siena without a car is to bus which takes 9h 25m and costs .
It takes approximately 9h 25m to get from Mulhouse to Siena, including transfers.
Mulhouse to Siena bus services, operated by Onebus, depart from Basel station.
Mulhouse to Siena train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Basel SBB station.
The best way to get from Mulhouse to Siena is to bus which takes 9h 25m and costs . Alternatively, you can train, which costs €95 - €550 and takes 10h 33m.
What companies run services between Mulhouse, France and Siena, Italy?
You can take a bus from Mulhouse to Siena via Basel Euroairport FR, Basel EuroAirport, Ankunft, Basel, Brausebad, Basel, and Florence Villa Constanza Bus Station in around 9h 25m. Alternatively, you can take a train from Mulhouse Ville to Siena via Basel Sbb, Basel SBB, Lugano, Milano Centrale, and Firenze S.M.N. in around 10h 33m.
- Website
- ita-airways.com
Flights from Zurich Airport to Florence Peretola Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- €100–250
Flights from Zurich Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 20m
- When
- Monday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €170–750
Flights from Basel to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 50m
- When
- Thursday and Sunday
- Estimated price
- €150–240
Flights from Zurich Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 3m
- When
- Every day
- Estimated price
- €85–290
Flights from Zurich Airport to Venice Marco Polo Airport
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- €85–320
- Website
- swiss.com
Flights from Zurich Airport to Florence Peretola Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- €100–250
Flights from Basel to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 50m
- When
- Thursday and Sunday
- Estimated price
- €150–240
Flights from Zurich Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 3m
- When
- Every day
- Estimated price
- €85–290
Flights from Zurich Airport to Venice Marco Polo Airport
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- €85–320
- Website
- lufthansa.com
Flights from Zurich Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 16m
- When
- Every day
- Estimated price
- €170–750
Flights from Basel to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 17m
- When
- Monday to Saturday
- Estimated price
- €190–850
Flights from Basel to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- €210–950
Flights from Basel to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 50m
- When
- Thursday and Sunday
- Estimated price
- €150–240
- Website
- austrian.com
Flights from Basel to Florence Peretola Airport via Vienna
- Ave. Duration
- 3h 45m
- When
- Monday to Friday
- Estimated price
- €120–430
- Website
- airdolomiti.it
Flights from Basel to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 6h 15m
- When
- Monday and Sunday
- Estimated price
- €210–950
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Basel SBB to Lugano
- Ave. Duration
- 2h 54m
- Frequency
- Every 3 hours
- Estimated price
- €90–280
- Website
- https://www.sbb.ch/en
Train from Lugano to Milano Centrale
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €28–85
- Website
- https://www.sbb.ch/en
- Phone
- +49 (0) 7531 915109
- [email protected]
- Website
- sbb-deutschland.de
Train from Basel SBB to Lugano
- Ave. Duration
- 3h 21m
- Frequency
- Once daily
- Estimated price
- €20–25
- Schedules at
- sbb-deutschland.de
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €45–90
- Schedules at
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 20 minutes
- Estimated price
- €13–27
- Schedules at
- trenitalia.com
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- €35–75
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 58m
- Frequency
- 4 times a day
- Estimated price
- €35–80
- Website
- https://www.italotreno.it/en
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- 5 times a day
- Estimated price
- €11–23
- Website
- https://www.italotreno.it/en
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 11m
- Frequency
- Once daily
- Estimated price
- €30–60
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- 3 times a day
- Estimated price
- €30–70
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- 3 times a day
- Estimated price
- €9–20
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Mulhouse Ville to Zuerich Hb
- Ave. Duration
- 1h 21m
- Frequency
- Every 3 hours
- Estimated price
- €25–40
- Website
- https://www.sncf-connect.com/en-en
Train from Mulhouse Ville to Zuerich Hb
- Ave. Duration
- 1h 21m
- Frequency
- Every 3 hours
- Estimated price
- €25–40
- Website
- https://www.sncf-connect.com/en-en
Train from Mulhouse Ville to Zuerich Hb
- Ave. Duration
- 1h 21m
- Frequency
- Every 3 hours
- Estimated price
- €25–40
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- onebus.it
Bus from Basel to Florence Villa Constanza Bus Station
- Ave. Duration
- 5h 46m
- Frequency
- Once a week
- Website
- https://onebus.it/
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- https://www.flixbus.fr
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 2 hours
- Estimated price
- €5–10
- Website
- https://www.flixbus.co.uk
Bus from Mulhouse to Milan
- Ave. Duration
- 5h 10m
- Frequency
- 6 times a week
- Estimated price
- €30–55
- Website
- https://www.flixbus.co.uk
Bus from Milano, Autostazione Lampugnano to Siena
- Ave. Duration
- 4h 55m
- Frequency
- Every 4 hours
- Estimated price
- €30–55
- Website
- https://www.flixbus.co.uk
- Phone
- +3 318 576 2228
- Website
- blablacar.co.uk
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- €5–11
- Website
- https://www.blablacar.co.uk/bus
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
5 incredible day trips from Florence by train
Read the travel guide
More Questions & Answers
Mulhouse to Siena bus services, operated by Onebus, arrive at Florence Villa Constanza Bus Station.
Mulhouse to Siena train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Lugano station.
Yes, the driving distance between Mulhouse to Siena is 733 km. It takes approximately 7h 36m to drive from Mulhouse to Siena.
Book your Mulhouse to Siena train tickets online with Omio.
Book your Mulhouse to Siena bus tickets online with Omio.
There are 2468+ hotels available in Siena.







































