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How to get fromMurphysboro to Cincinnatiby train, bus, car, plane, bus (Flixbus, Amtrak), or bus (Flixbus)

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There are 7 ways to get from Murphysboro to Cincinnati by train, bus, car, plane, bus (Flixbus, Amtrak), or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus via Dayton

    best
    1. Take the train from Carbondale to Champaign-Urbanatrain train
    2. Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Dayton Trotwood Bus Stationbus bus
    4. Take the bus from Dayton Trotwood Bus Station to Cincinnatibus bus
    11h 6m
    $102–210

  2. Drive 322.8 mi

    cheapest
    1. Drive from Murphysboro to Cincinnaticar car 322.8 mi
    5h 57m
    $59–86

  3. Fly from Williamson County Regional Airport

    1. Fly from Williamson County Regional Airport (MWA) to Covington (CVG)plane plane MWA - CVG
    8h 31m
    $161–710

  4. Train, bus

    1. Take the train from Carbondale to Champaign-Urbanatrain train
    2. Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis, IN to Greyhound Station Cincinnatibus bus
    11h 16m
    $94–248

  5. Bus

    1. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    2. Take the bus from Nashville to Louisville, KYbus bus
    3. Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus bus
    11h 26m
    $86–168

  6. Bus via Newburg

    1. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    2. Take the bus from Tornado Bus Co - Nashville to La Tropicana - Louisville, KYbus bus
    3. Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus bus
    12h 46m
    $94–183

  7. Bus to Lambert–St. Louis International Airport, fly

    1. Take the bus from Carbondale to St. Louisbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Covington (CVG)plane plane STL - CVG
    7h 59m
    $637–1,023

Williamson County Regional Airport (MWA) to Covington (CVG) flights

Calendar15Weekly Planes
Duration7h 15mAverage Duration
Ticket$116Cheapest Price
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Questions & Answers

Map of how to get from Murphysboro to Cincinnati.ExpandLaunch map view
  • Distance: 468.5 mi
  • Duration: 11h 6m

What companies run services between Murphysboro, IL, USA and Cincinnati, OH, USA?

American Airlines and Southwest Airlines fly from Williamson County Regional Airport (MWA) to Covington (CVG) twice daily. Alternatively, you can take a vehicle from Murphysboro to Cincinnati - Downtown via Carbondale Intermodal Station, Nashville, and Louisville, KY Bus Station in around 11h 26m.

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Bus operators

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