There are 6 ways to get from Murphysboro to Cincinnati by plane, train, bus, car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Williamson County Regional Airport
best- Fly from Williamson County Regional Airport (MWA) to Covington (CVG)plane MWA - CVG
5h 54m$151–660Drive 322.8 mi
cheapest- Drive from Murphysboro to Cincinnaticar 322.8 mi
5h 57m$59–86Train, bus
- Take the train from Carbondale to Champaign-Urbanatrain
- Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus
- Take the bus from Indianapolis to Cincinnatibus
11h 11m$149–298Drive to Barkley Regional Airport, fly
- Drive from Murphysboro to Barkley Regional Airport (PAH)car
- Fly from Barkley Regional Airport (PAH) to Covington (CVG)plane PAH - CVG
7h 34m$116–622Bus to Lambert–St. Louis International Airport, fly
- Take the bus from Carbondale Intermodal Station to St Louis Bus Stationbus
- Fly from Lambert–St. Louis International Airport (STL) to Covington (CVG)plane STL - CVG
7h 54m$139–701Bus
- Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus FlixBus N2521
- Take the bus from Nashville Bus Station to Cincinnati Bus Stationbus Greyhound US0105 / ...
11h 51m$100–183
Williamson County Regional Airport (MWA) to Covington (CVG) flights
Comparing Your Travel Options
The cheapest way to get from Murphysboro to Cincinnati is to drive which costs $55 - $85 and takes 5h 57m.
The fastest way to get from Murphysboro to Cincinnati is to fly which takes 5h 54m and costs $150 - $700.
No, there is no direct bus from Murphysboro station to Cincinnati. However, there are services departing from Carbondale Intermodal Station and arriving at Cincinnati via Nashville Bus Station and Cincinnati. The journey, including transfers, takes approximately 11h 51m.
The distance between Murphysboro and Cincinnati is 287 miles. The road distance is 324.6 miles.
The best way to get from Murphysboro to Cincinnati without a car is to train and bus which takes 11h 11m and costs $140 - $300.
It takes approximately 5h 54m to get from Murphysboro to Cincinnati, including transfers.
Murphysboro to Cincinnati bus services, operated by Flixbus USA, depart from Carbondale Intermodal Station.
The best way to get from Murphysboro to Cincinnati is to fly which takes 5h 54m and costs $150 - $700. Alternatively, you can bus, which costs $100 - $190 and takes 11h 51m.
Murphysboro to Cincinnati bus services, operated by Flixbus USA, arrive at Nashville Bus Station.
Cincinnati is 1h ahead of Murphysboro. It is currently 2:13 AM in Murphysboro and 3:13 AM in Cincinnati.
What companies run services between Murphysboro, IL, USA and Cincinnati, OH, USA?
American Airlines flies from Williamson County Regional Airport (MWA) to Covington (CVG) once daily. Alternatively, you can take a vehicle from Murphysboro to Cincinnati via Carbondale Intermodal Station, Nashville Bus Station, Cincinnati Bus Station, and Cincinnati in around 11h 51m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Covington via Chicago Midway
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- $100–650
Flights from Lambert–St. Louis International Airport to Covington via Nashville
- Ave. Duration
- 3h 42m
- When
- Every day
- Estimated price
- $100–650
- Website
- united.com
Flights from Barkley Regional Airport to Covington via Chicago O'Hare
- Ave. Duration
- 6h 50m
- When
- Every day
- Estimated price
- $100–600
Flights from Barkley Regional Airport to Covington via Houston
- Ave. Duration
- 8h 35m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $190–850
Flights from Lambert–St. Louis International Airport to Covington via Chicago O'Hare
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $110–650
- Website
- aa.com
Flights from Williamson County Regional Airport to Covington via Chicago O'Hare
- Ave. Duration
- 6h 1m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–600
Flights from Lambert–St. Louis International Airport to Covington via Chicago O'Hare
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $110–650
Flights from Lambert–St. Louis International Airport to Covington via Charlotte
- Ave. Duration
- 4h 32m
- When
- Wednesday, Thursday, Friday, Saturday, Monday, and Sunday
- Estimated price
- $150–800
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Covington via Detroit
- Ave. Duration
- 3h 37m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–700
Flights from Lambert–St. Louis International Airport to Covington via Atlanta
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $140–800
Flights from Lambert–St. Louis International Airport to Covington via Minneapolis
- Ave. Duration
- 4h 39m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $160–850
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Carbondale to Champaign-Urbana
- Ave. Duration
- 2h 50m
- Frequency
- 3 times a day
- Estimated price
- $95–160
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Champaign Intermodal Trans Ctr to Indianapolis Union Station
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $21–35
- Website
- Greyhound
Bus from Nashville Bus Station to Cincinnati Bus Station
- Ave. Duration
- 5h 35m
- Frequency
- Twice daily
- Estimated price
- $50–80
- Website
- Greyhound
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Indianapolis to Cincinnati
- Ave. Duration
- 2h 55m
- Frequency
- Twice daily
- Estimated price
- $13–50
- Website
- Barons Bus
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Carbondale Intermodal Station to St Louis Bus Station
- Ave. Duration
- 1h 55m
- Frequency
- 5 times a week
- Estimated price
- $15–23
- Schedules at
- Flixbus USA
Bus from Carbondale Intermodal Station to Nashville Bus Station
- Ave. Duration
- 3h 50m
- Frequency
- 5 times a week
- Estimated price
- $30–50
- Schedules at
- Flixbus USA
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Carbondale Intermodal Station to St Louis Bus Station
- Ave. Duration
- 2h
- Frequency
- Once daily
- Website
- Amtrak
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Booking & Getting There
Yes, the driving distance between Murphysboro to Cincinnati is 325 miles. It takes approximately 5h 57m to drive from Murphysboro to Cincinnati.
There are 668+ hotels available in Cincinnati.










