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How to get fromMurphysboro to Kansas Cityby bus (Amtrak, Flixbus, Greyhound), bus, train, car, or plane

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There are 7 ways to get from Murphysboro to Kansas City by bus (Amtrak, Flixbus, Greyhound), bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Carbondale to St. Louisbus bus Amtrak Thruway Connecting Service
    2. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus Greyhound US0180s / ...
    7h 11m
    $74–116
  2. Drive  333.1 mi

    cheapest
    1. Drive from Murphysboro to Kansas Citycar car 333.1 mi
    6h 3m
    $55–80
  3. Bus, train

    1. Take the bus from Carbondale to St. Louisbus bus Amtrak Thruway Connecting Service
    2. Take the train from St. Louis to Kansas Citytrain train Missouri River Runner / ...
    8h 51m
    $184–286
  4. Fly from Williamson County Regional Airport

    1. Fly from Williamson County Regional Airport (MWA) to Kansas City (MCI)plane plane MWA - MCI
    6h 34m
    $159–708
  5. Bus to Lambert–St. Louis International Airport, fly

    1. Take the bus from Carbondale to St. Louisbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Kansas City (MCI)plane plane STL - MCI
    6h 37m
    $122–649
  6. Drive to Barkley Regional Airport, fly

    1. Drive from Murphysboro to Barkley Regional Airport (PAH)car car
    2. Fly from Barkley Regional Airport (PAH) to Kansas City (MCI)plane plane PAH - MCI
    8h 1m
    $132–668
  7. Bus to Nashville, fly

    1. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    2. Fly from Nashville (BNA) to Kansas City (MCI)plane plane BNA - MCI
    9h 3m
    $161–775

Williamson County Regional Airport (MWA) to Kansas City (MCI) flights

Calendar11Weekly Planes
Duration4h 48mAverage Duration
Ticket$118Cheapest Price
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Comparing Your Travel Options

What companies run services between Murphysboro, IL, USA and Kansas City, MO, USA?

You can take a vehicle from Murphysboro to Kansas City Bus Station via Carbondale, St. Louis, and St Louis Bus Station in around 7h 11m. Alternatively, American Airlines flies from Williamson County Regional Airport (MWA) to Kansas City (MCI) twice daily.

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Train operators
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