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How to get fromMurphysboro to New Orleansby train (Amtrak), car, plane, bus, or taxi

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There are 7 ways to get from Murphysboro to New Orleans by train (Amtrak), car, plane, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Carbondale to New Orleans Union Passenger Terminaltrain train City of New Orleans
    14h 4m
    $359–573

  2. Drive  607.5 mi

    cheapest
    1. Drive from Murphysboro to New Orleanscar car 607.5 mi
    10h 12m
    $111–161

  3. Fly from Williamson County Regional Airport

    1. Fly from Williamson County Regional Airport (MWA) to Louis Armstrong New Orleans International Airport (MSY)plane plane MWA - MSY
    9h 10m
    $180–711

  4. Drive to Barkley Regional Airport, fly

    1. Drive from Murphysboro to Barkley Regional Airport (PAH)car car
    2. Fly from Barkley Regional Airport (PAH) to Louis Armstrong New Orleans International Airport (MSY)plane plane PAH - MSY
    7h 56m
    $125–623

  5. Bus to Lambert–St. Louis International Airport, fly

    1. Take the bus from Carbondale Intermodal Station to St Louis Bus Stationbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Louis Armstrong New Orleans International Airport (MSY)plane plane STL - MSY
    6h 38m
    $508–902

  6. Bus to Nashville, fly

    1. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    2. Fly from Nashville (BNA) to Louis Armstrong New Orleans International Airport (MSY)plane plane BNA - MSY
    8h 24m
    $902–1,078

  7. Taxi, bus to Evansville, fly

    1. Take the taxi from Murphysboro to Mount Vernontaxi taxi
    2. Take the bus from Mount Vernon to Evansville Bus Stationbus bus
    3. Fly from Evansville (EVV) to Louis Armstrong New Orleans International Airport (MSY)plane plane EVV - MSY
    9h 22m
    $266–753

Williamson County Regional Airport (MWA) to Louis Armstrong New Orleans International Airport (MSY) flights

Calendar16Weekly Planes
Duration9h 51mAverage Duration
Ticket$132Cheapest Price
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Comparing Your Travel Options

Map of how to get from Murphysboro to New Orleans.ExpandLaunch map view
  • Distance: 630.7 mi
  • Duration: 14h 4m

What companies run services between Murphysboro, IL, USA and New Orleans, LA, USA?

Amtrak operates a train from Carbondale to New Orleans Union Passenger Terminal once daily. Tickets cost $340–550 and the journey takes 13h 53m. Alternatively, American Airlines and Southwest Airlines fly from Williamson County Regional Airport (MWA) to Louis Armstrong New Orleans International Airport (MSY) twice daily.

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