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How to get fromMurphysboro to New Orleansby plane, train (Amtrak), car, bus, or taxi

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There are 7 ways to get from Murphysboro to New Orleans by plane, train (Amtrak), car, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Williamson County Regional Airport

    best
    1. Fly from Williamson County Regional Airport (MWA) to Louis Armstrong New Orleans International Airport (MSY)plane plane MWA - MSY
    7h 47m
    $180–711

  2. Drive  607.5 mi

    cheapest
    1. Drive from Murphysboro to New Orleanscar car 607.5 mi
    10h 12m
    $108–155

  3. Train (Amtrak)

    1. Take the train from Carbondale to New Orleans Union Passenger Terminaltrain train City of New Orleans
    14h 4m
    $359–573

  4. Drive to Barkley Regional Airport, fly

    1. Drive from Murphysboro to Barkley Regional Airport (PAH)car car
    2. Fly from Barkley Regional Airport (PAH) to Louis Armstrong New Orleans International Airport (MSY)plane plane PAH - MSY
    7h 56m
    $124–622

  5. Bus to Lambert–St. Louis International Airport, fly

    1. Take the bus from Carbondale to St. Louisbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Louis Armstrong New Orleans International Airport (MSY)plane plane STL - MSY
    6h 48m
    $138–652

  6. Bus to Nashville, fly

    1. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    2. Fly from Nashville (BNA) to Louis Armstrong New Orleans International Airport (MSY)plane plane BNA - MSY
    8h 24m
    $752–1,078

  7. Taxi, bus to Evansville, fly

    1. Take the taxi from Murphysboro to Mount Vernontaxi taxi
    2. Take the bus from Mount Vernon to Evansville Bus Stationbus bus
    3. Fly from Evansville (EVV) to Louis Armstrong New Orleans International Airport (MSY)plane plane EVV - MSY
    9h 22m
    $266–754

Williamson County Regional Airport (MWA) to Louis Armstrong New Orleans International Airport (MSY) flights

Calendar27Weekly Planes
Duration9h 37mAverage Duration
Ticket$134Cheapest Price
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Comparing Your Travel Options

Map of how to get from Murphysboro to New Orleans.ExpandLaunch map view
  • Distance: 572.9 mi
  • Duration: 7h 47m

What companies run services between Murphysboro, IL, USA and New Orleans, LA, USA?

American Airlines, United Airlines, and Southwest Airlines fly from Williamson County Regional Airport (MWA) to Louis Armstrong New Orleans International Airport (MSY) 4 times a day. Alternatively, Amtrak operates a train from Carbondale to New Orleans Union Passenger Terminal once daily. Tickets cost $340–550 and the journey takes 13h 53m.

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