There are 7 ways to get from Murrells Inlet to Chicago by plane, bus (Greyhound, Flixbus), car, train, bus (Greyhound), or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Chicago Midway International Airport
best- Fly from Myrtle Beach (MYR) to Chicago Midway International Airport (MDW)plane MYR - MDW
3h 13m$113–433Fly to Chicago O'Hare International Airport
cheapest- Fly from Myrtle Beach (MYR) to Chicago O'Hare International Airport (ORD)plane MYR - ORD
3h 47m$93–343Bus via Atlanta
- Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus Greyhound US0641S
- Take the bus from Atlanta Bus Station to Chicago Bus Stationbus Greyhound US0100
26h 16m$218–341Drive, train (Amtrak)
- Drive from Murrells Inlet to Kingstree Stationcar
- Take the train from Kingstree Station to Petersburg Amtrak Stationtrain
- Take the train from Petersburg Amtrak Station to Chicago Union Stationtrain
29h 46m$671–1,077Drive 904 mi
- Drive from Murrells Inlet to Chicagocar 904 mi
16h 43m$165–239Bus
- Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus
- Take the bus from Fayetteville to Winston-Salembus
- Take the bus from Winston Salem to Columbusbus
- Take the bus from Columbus to Chicagobus
27h 16m$164–301Bus, train
- Take the bus from Myrtle Beach Bus Station to Raleigh Bus Stationbus Greyhound US0645S
- Take the train from Raleigh Union Station to Chicago Union Stationtrain Floridian
31h 8m$632–1,065
Myrtle Beach (MYR) to Chicago Midway International Airport (MDW) flights
Comparing Your Travel Options
The cheapest way to get from Murrells Inlet to Chicago is to drive which costs $160 - $240 and takes 16h 43m.
The fastest way to get from Murrells Inlet to Chicago is to fly which takes 3h 13m and costs $110 - $440.
No, there is no direct bus from Murrells Inlet station to Chicago station. However, there are services departing from Myrtle Beach Bus Station and arriving at Chicago Bus Station via Atlanta Bus Station. The journey, including transfers, takes approximately 26h 16m.
The distance between Murrells Inlet and Chicago is 767 miles. The road distance is 909.2 miles.
The best way to get from Murrells Inlet to Chicago without a car is to bus via Atlanta which takes 26h 16m and costs $210 - $350.
It takes approximately 3h 13m to get from Murrells Inlet to Chicago, including transfers.
Murrells Inlet to Chicago bus services, operated by Greyhound USA, depart from Myrtle Beach Bus Station.
The best way to get from Murrells Inlet to Chicago is to fly which takes 3h 13m and costs $110 - $440. Alternatively, you can bus via Atlanta, which costs $210 - $350 and takes 26h 16m.
Murrells Inlet to Chicago bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Chicago is 1h behind Murrells Inlet. It is currently 12:27 PM in Murrells Inlet and 11:27 AM in Chicago.
What companies run services between Murrells Inlet, SC, USA and Chicago, IL, USA?
Southwest Airlines and Delta fly from Myrtle Beach (MYR) to Chicago Midway International Airport (MDW) 3 times a day. Alternatively, you can take a vehicle from Murrells Inlet to Chicago Bus Station via Myrtle Beach Bus Station and Atlanta Bus Station in around 26h 16m.
- Website
- aa.com
Flights from Myrtle Beach to Chicago O'Hare International Airport
- Ave. Duration
- 2h 38m
- When
- Every day
- Estimated price
- $50–290
Flights from Myrtle Beach to Chicago O'Hare International Airport via Charlotte
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $50–290
- Website
- delta.com
Flights from Myrtle Beach to Chicago Midway International Airport via Atlanta
- Ave. Duration
- 4h 49m
- When
- Every day
- Estimated price
- $75–410
Flights from Myrtle Beach to Chicago O'Hare International Airport via Atlanta
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $60–310
Flights from Myrtle Beach to Chicago O'Hare International Airport via Detroit
- Ave. Duration
- 6h 9m
- When
- Every day
- Estimated price
- $55–300
- Website
- southwest.com
Flights from Myrtle Beach to Chicago Midway International Airport
- Ave. Duration
- 2h 10m
- When
- Monday to Wednesday
- Estimated price
- $70–380
Flights from Myrtle Beach to Chicago Midway International Airport via Nashville
- Ave. Duration
- 4h 22m
- When
- Monday, Sunday, and Saturday
- Estimated price
- $75–400
- Website
- united.com
Flights from Myrtle Beach to Chicago O'Hare International Airport
- Ave. Duration
- 2h 45m
- When
- Every day
- Estimated price
- $50–290
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Kingstree Station to Petersburg Amtrak Station
- Ave. Duration
- 5h 31m
- Frequency
- Twice daily
- Estimated price
- $170–260
- Website
- Amtrak
Train from Petersburg Amtrak Station to Chicago Union Station
- Ave. Duration
- 21h 41m
- Frequency
- Once daily
- Estimated price
- $490–800
- Website
- Amtrak
Train from Raleigh Union Station to Chicago Union Station
- Ave. Duration
- 24h 28m
- Frequency
- Once daily
- Estimated price
- $550–950
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Myrtle Beach Bus Station to Atlanta Bus Station
- Ave. Duration
- 8h 55m
- Frequency
- Once daily
- Estimated price
- $65–100
- Website
- Greyhound
Bus from Atlanta Bus Station to Chicago Bus Station
- Ave. Duration
- 16h
- Frequency
- 4 times a day
- Estimated price
- $120–190
- Website
- Greyhound
Bus from Myrtle Beach Bus Station to Fayetteville Bus Station
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $27–45
- Website
- Greyhound
Bus from Myrtle Beach Bus Station to Raleigh Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- Once daily
- Estimated price
- $35–60
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Atlanta Bus Station to Chicago Bus Station
- Ave. Duration
- 16h 10m
- Frequency
- 3 times a day
- Estimated price
- $110–170
- Schedules at
- Flixbus USA
- Phone
- +1 704-348-1200
- [email protected]
- Website
- Sunway Charters
Bus from Fayetteville to Winston-Salem
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $24–35
- Schedules at
- Sunway Charters
- Passenger
- $24–35
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Winston Salem to Columbus
- Ave. Duration
- 9h 40m
- Frequency
- Once daily
- Estimated price
- $40–90
- Website
- Barons Bus
Bus from Columbus to Chicago
- Ave. Duration
- 7h 15m
- Frequency
- Twice daily
- Estimated price
- $30–80
- Website
- Barons Bus
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Booking & Getting There
Yes, the driving distance between Murrells Inlet to Chicago is 909 miles. It takes approximately 16h 43m to drive from Murrells Inlet to Chicago.
There are 1130+ hotels available in Chicago.










