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How to get fromMurrells Inlet to Fort Myersby plane, bus, train, car, or bus (Greyhound, Flixbus)

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There are 10 ways to get from Murrells Inlet to Fort Myers by plane, bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Myrtle Beach to Ft. Myers

    best
    1. Fly from Myrtle Beach (MYR) to Ft. Myers (RSW)plane plane MYR - RSW
    6h 49m
    $124–503

  2. Drive  609.7 mi

    cheapest
    1. Drive from Murrells Inlet to Fort Myerscar car 609.7 mi
    11h 22m
    $112–161

  3. Bus, train via Jacksonville

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    2. Take the train from Charleston Amtrak Station to Jacksonvilletrain train
    3. Take the bus from Jacksonville to Wildwood Amtrak Stationbus bus
    4. Take the bus from Wildwood to Fort Myersbus bus
    18h 13m
    $208–356

  4. Drive, train, bus

    1. Drive from Murrells Inlet to Kingstree Stationcar car
    2. Take the train from Kingstree Station to Fort Lauderdale Amtrak Stationtrain train
    3. Take the bus from Fort Lauderdale International Airport to Fort Myers Bus Stopbus bus
    20h 4m
    $191–462

  5. Fly Myrtle Beach to Fort Lauderdale–Hollywood International Airport, bus

    1. Fly from Myrtle Beach (MYR) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane MYR - FLL
    2. Take the bus from Fort Lauderdale International Airport to Fort Myers Bus Stopbus bus
    5h 48m
    $200–488

  6. Fly Myrtle Beach to Tampa, bus

    1. Fly from Myrtle Beach (MYR) to Tampa (TPA)plane plane MYR - TPA
    2. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    7h 13m
    $153–420

  7. Fly Myrtle Beach to Orlando, bus

    1. Fly from Myrtle Beach (MYR) to Orlando (MCO)plane plane MYR - MCO
    2. Take the bus from Orlando to Fort Myers Bus Stopbus bus
    9h 24m
    $173–315

  8. Bus to Wilmington International Airport, fly to Ft. Myers

    1. Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus bus
    2. Fly from Wilmington International Airport (ILM) to Ft. Myers (RSW)plane plane ILM - RSW
    7h 7m
    $167–593

  9. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    2. Take the train from Charleston Amtrak Station to Winter Park Amtrak Stationtrain train
    3. Take the bus from Orlando to Fort Myers Bus Stopbus bus
    19h 19m
    $185–363

  10. Bus

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the bus from Fayetteville Bus Station to Orlando Bus Stationbus bus
    3. Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus bus
    20h 26m
    $177–271

Myrtle Beach (MYR) to Ft. Myers (RSW) flights

Calendar56Weekly Planes
Duration5h 33mAverage Duration
Ticket$84Cheapest Price
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Comparing Your Travel Options

Map of how to get from Murrells Inlet to Fort Myers.ExpandLaunch map view
  • Distance: 550.2 mi
  • Duration: 6h 49m

What companies run services between Murrells Inlet, SC, USA and Fort Myers, FL, USA?

Southwest Airlines, Delta, and American Airlines fly from Myrtle Beach (MYR) to Ft. Myers (RSW) every 4 hours. Alternatively, you can take a vehicle from Murrells Inlet to Fort Myers Bus Stop via Myrtle Beach Bus Station, Fayetteville Bus Station, and Orlando Bus Station in around 20h 26m.

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