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How to get fromMurrells Inlet to Louisvilleby plane, bus (Greyhound, Flixbus, Amtrak), car, or bus (Greyhound, Flixbus)

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There are 4 ways to get from Murrells Inlet to Louisville by plane, bus (Greyhound, Flixbus, Amtrak), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Myrtle Beach (MYR) to Louisville International Airport (SDF)plane plane MYR - SDF
    5h 1m
    $137–651

  2. Drive  618.1 mi

    cheapest
    1. Drive from Murrells Inlet to Louisvillecar car 618.1 mi
    12h 44m
    $113–163

  3. Bus

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville to Louisville, KYbus bus
    19h 11m
    $173–271

  4. Bus via Preston @ Vim

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Tornado Bus Co - Nashville to La Tropicana - Louisville, KYbus bus
    20h 3m
    $181–286

Myrtle Beach (MYR) to Louisville International Airport (SDF) flights

Calendar87Weekly Planes
Duration5h 6mAverage Duration
Ticket$99Cheapest Price
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Comparing Your Travel Options

Map of how to get from Murrells Inlet to Louisville.ExpandLaunch map view
  • Distance: 511.2 mi
  • Duration: 5h 1m

What companies run services between Murrells Inlet, SC, USA and Louisville, KY, USA?

American Airlines, Southwest Airlines, and Delta fly from Myrtle Beach (MYR) to Louisville International Airport (SDF) every 2 hours. Alternatively, you can take a vehicle from Murrells Inlet to Louisville, KY via Myrtle Beach Bus Station, Atlanta Bus Station, and Nashville in around 19h 11m.

Airlines
Bus operators

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