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How to get fromMurrells Inlet to Panama Cityby plane, bus, or car

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There are 6 ways to get from Murrells Inlet to Panama City by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Northwest Florida Beaches International Airport

    best
    1. Fly from Myrtle Beach (MYR) to Northwest Florida Beaches International Airport (ECP)plane plane MYR - ECP
    4h 26m
    $166–448

  2. Drive 519.2 mi

    cheapest
    1. Drive from Murrells Inlet to Panama Citycar car 519.2 mi
    10h 39m
    $95–137

  3. Bus, drive

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Orangebus bus
    3. Take the bus from Orange to Crestviewbus bus
    4. Drive from Crestview to Front Beach Rd. & Back Beach Rd.car car
    39h 13m
    $313–512

  4. Fly to Destin–Fort Walton Beach Airport, drive

    1. Fly from Myrtle Beach (MYR) to Destin–Fort Walton Beach Airport (VPS)plane plane MYR - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama Citycar car
    5h 33m
    $113–396

  5. Fly to Dothan Regional Airport, drive

    1. Fly from Myrtle Beach (MYR) to Dothan Regional Airport (DHN)plane plane MYR - DHN
    2. Drive from Dothan Regional Airport (DHN) to Panama Citycar car
    7h 47m
    $112–382

  6. Fly to Tallahassee, drive

    1. Fly from Myrtle Beach (MYR) to Tallahassee (TLH)plane plane MYR - TLH
    2. Drive from Tallahassee (TLH) to Panama Citycar car
    5h 57m
    $128–464

Myrtle Beach (MYR) to Northwest Florida Beaches International Airport (ECP) flights

Calendar47Weekly Planes
Duration5hAverage Duration
Ticket$60Cheapest Price
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Questions & Answers

Map of how to get from Murrells Inlet to Panama City.ExpandLaunch map view
  • Distance: 499.8 mi
  • Duration: 4h 26m

What companies run services between Murrells Inlet, SC, USA and Panama City, FL, USA?

Delta, American Airlines, and Southwest Airlines fly from Myrtle Beach (MYR) to Northwest Florida Beaches International Airport (ECP) every 4 hours.

Airlines
Bus operators

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