There are 5 ways to get from Murrells Inlet to Port Saint Lucie by plane, bus, train, bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Fort Lauderdale–Hollywood International Airport, bus
best- Fly from Myrtle Beach (MYR) to Fort Lauderdale–Hollywood International Airport (FLL)plane MYR - FLL
- Take the bus from Fort Lauderdale - Broward Blvd Park and Ride to Fort Piercebus
6h 1m$211–513Drive 551.6 mi
cheapest- Drive from Murrells Inlet to Port Saint Luciecar 551.6 mi
9h 49m$101–146Bus, train
- Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus
- Take the train from Charleston Amtrak Station to Kissimmee Amtrak Stationtrain
- Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus
15h 58m$199–370Bus (Greyhound)
- Take the bus from Myrtle Beach Bus Station to Camdenbus
- Take the bus from Camden to Jacksonvillebus
- Take the bus from Jacksonville to Port St Luciebus
20h 50m$139–251Fly to Orlando, bus
- Fly from Myrtle Beach (MYR) to Orlando (MCO)plane MYR - MCO
- Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus
6h 31m$175–342
Myrtle Beach (MYR) to Fort Lauderdale–Hollywood International Airport (FLL) flights
Questions & Answers
The cheapest way to get from Murrells Inlet to Port Saint Lucie is to drive which costs $100 - $150 and takes 9h 49m.
The fastest way to get from Murrells Inlet to Port Saint Lucie is to fly and bus which takes 6h 1m and costs $210 - $550.
No, there is no direct bus from Murrells Inlet station to Port Saint Lucie. However, there are services departing from Myrtle Beach Bus Station and arriving at SW PSL Blvd & SE Bayshore Blvd via Camden, Jacksonville and SW Gatlin Blvd & SW Brescia St. The journey, including transfers, takes approximately 20h 50m.
The distance between Murrells Inlet and Port Saint Lucie is 645 miles. The road distance is 554.8 miles.
The best way to get from Murrells Inlet to Port Saint Lucie without a car is to bus and train which takes 15h 58m and costs $190 - $370.
It takes approximately 6h 1m to get from Murrells Inlet to Port Saint Lucie, including transfers.
Murrells Inlet to Port Saint Lucie bus services, operated by Greyhound USA, depart from Myrtle Beach Bus Station.
Murrells Inlet to Port Saint Lucie bus services, operated by Greyhound USA, arrive at Camden station.
Yes, the driving distance between Murrells Inlet to Port Saint Lucie is 555 miles. It takes approximately 9h 49m to drive from Murrells Inlet to Port Saint Lucie.
There are 534+ hotels available in Port Saint Lucie.
What companies run services between Murrells Inlet, SC, USA and Port Saint Lucie, FL, USA?
You can take a vehicle from Murrells Inlet to SW PSL Blvd & SE Bayshore Blvd via Myrtle Beach Bus Station, Camden, Jacksonville, and SW Gatlin Blvd & SW Brescia St in around 20h 50m.
- Website
- flybreeze.com
Flights from Myrtle Beach to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 57m
- When
- Every day
- Estimated price
- $140–410
Flights from Myrtle Beach to Orlando
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $100–250
- Website
- delta.com
Flights from Myrtle Beach to Fort Lauderdale–Hollywood International Airport via Atlanta
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $80–400
Flights from Myrtle Beach to Orlando via Atlanta
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $70–360
- Website
- aa.com
Flights from Myrtle Beach to Fort Lauderdale–Hollywood International Airport via Charlotte
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $75–380
Flights from Myrtle Beach to Orlando via Charlotte
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $60–350
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Charleston Amtrak Station to Kissimmee Amtrak Station
- Ave. Duration
- 8h 42m
- Frequency
- Once daily
- Estimated price
- $110–250
- Website
- Amtrak
- Phone
- (+1) 407 649 4994
- [email protected]
- Website
- Jet Set Express
Bus from Fort Lauderdale - Broward Blvd Park and Ride to Fort Pierce
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $29–40
- Website
- Jet Set Express
- Schedules at
- Jet Set Express
- Book at
- Jet Set Express
- Adult
- $29–40
Bus from Kissimmee -1471 East Osceola Parkway to Fort Pierce
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $30–40
- Website
- Jet Set Express
- Schedules at
- Jet Set Express
- Book at
- Jet Set Express
- Adult
- $30–40
Bus from Kissimmee -1471 East Osceola Parkway to Fort Pierce
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $30–40
- Website
- Jet Set Express
- Schedules at
- Jet Set Express
- Book at
- Jet Set Express
- Adult
- $30–40
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Myrtle Beach Bus Station to Charleston Bus Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $14–27
- Website
- Greyhound
Bus from Myrtle Beach Bus Station to Camden
- Ave. Duration
- 3h 15m
- Frequency
- Once daily
- Estimated price
- $16–35
- Website
- Greyhound
Bus from Camden to Jacksonville
- Ave. Duration
- 7h 30m
- Frequency
- Once daily
- Estimated price
- $45–95
- Website
- Greyhound
Bus from Jacksonville to Port St Lucie
- Ave. Duration
- 6h 25m
- Frequency
- Once daily
- Estimated price
- $35–70
- Website
- Greyhound
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