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How to get fromMuscatine to Louisvilleby taxi, plane, car, bus, or train

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There are 7 ways to get from Muscatine to Louisville by taxi, plane, car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Quad City International Airport, fly

    best
    1. Take the taxi from Muscatine to Moline-Airport-MLItaxi taxi
    2. Fly from Quad City International Airport (MLI) to Louisville International Airport (SDF)plane plane MLI - SDF
    5h 53m
    $176–562

  2. Drive, bus

    cheapest
    1. Drive from Muscatine to Galesburgcar car
    2. Take the bus from Galesburg to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    10h 5m
    $75–144

  3. Drive, train, bus (Amtrak)

    1. Drive from Muscatine to Galesburg Amtrak Stationcar car
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    13h 50m
    $150–304

  4. Drive 435.1 mi

    1. Drive from Muscatine to Louisvillecar car 435.1 mi
    7h 36m
    $80–115

  5. Drive to The Eastern Iowa Airport, fly

    1. Drive from Muscatine to Cedar-Rapids-Airport-CIDcar car
    2. Fly from The Eastern Iowa Airport (CID) to Louisville International Airport (SDF)plane plane CID - SDF
    6h 10m
    $162–918

  6. Taxi, bus

    1. Take the taxi from Muscatine to Moline Center Stationtaxi taxi
    2. Take the bus from Moline Center Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Union Station to Louisville, KYbus bus
    13h 8m
    $179–235

  7. Taxi, bus, train

    1. Take the taxi from Muscatine to Miller Containertaxi taxi
    2. Take the bus from Moline Center Station to Chicago Bus Stationbus bus
    3. Take the train from Chicago Union Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    15h 59m
    $198–329

Quad City International Airport (MLI) to Louisville International Airport (SDF) flights

Calendar81Weekly Planes
Duration5h 13mAverage Duration
Ticket$75Cheapest Price
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Questions & Answers

Map of how to get from Muscatine to Louisville.ExpandLaunch map view
  • Distance: 377.3 mi
  • Duration: 5h 53m

What companies run services between Muscatine, IA, USA and Louisville, KY, USA?

There is no direct connection from Muscatine to Louisville. However, you can take the taxi to Moline-Airport-MLI airport, fly to Louisville International Airport (SDF), walk to Louisville International Airport, then take the line 02 bus to 2nd @ York. Alternatively, you can take a vehicle from Muscatine to Louisville, KY via Galesburg and Indianapolis Union Station in around 10h 5m.

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