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How to get fromMuscatine to Mayo Clinicby taxi, bus, car, train, or plane

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There are 7 ways to get from Muscatine to Mayo Clinic by taxi, bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, bus

    best
    1. Take the taxi from Muscatine to Iowa Citytaxi taxi
    2. Take the bus from Iowa City to Des Moinesbus bus
    3. Take the bus from Des Moines to Minneapolis Bus Stationbus bus
    4. Take the bus from Minneapolis to Rochesterbus bus
    11h 45m
    $220–294

  2. Drive  228.7 mi

    cheapest
    1. Drive from Muscatine to Mayo Cliniccar car 228.7 mi
    4h 30m
    $42–61

  3. Drive, train, bus

    1. Drive from Muscatine to Galesburg Amtrak Stationcar car
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    4. Take the bus from St. Paul to Rochesterbus bus
    15h 35m
    $346–549

  4. Drive to The Eastern Iowa Airport, fly to Rochester

    1. Drive from Muscatine to Cedar-Rapids-Airport-CIDcar car
    2. Fly from The Eastern Iowa Airport (CID) to Rochester (RST)plane plane CID - RST
    7h 4m
    $57–375

  5. Taxi, bus via Chicago

    1. Take the taxi from Muscatine to Miller Containertaxi taxi
    2. Take the bus from Moline Center Station to Chicago Bus Stationbus bus
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to Rochesterbus bus
    16h 24m
    $189–279

  6. Taxi to Quad City International Airport, fly to Rochester

    1. Take the taxi from Muscatine to Moline-Airport-MLItaxi taxi
    2. Fly from Quad City International Airport (MLI) to Rochester (RST)plane plane MLI - RST
    6h 16m
    $156–499

  7. Drive to The Eastern Iowa Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Drive from Muscatine to Cedar-Rapids-Airport-CIDcar car
    2. Fly from The Eastern Iowa Airport (CID) to Minneapolis–Saint Paul International Airport (MSP)plane plane CID - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    5h 43m
    $111–445

The Eastern Iowa Airport (CID) to Rochester (RST) flights

Calendar48Weekly Planes
Duration5h 21mAverage Duration
Ticket$48Cheapest Price
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Comparing Your Travel Options

Map of how to get from Muscatine to Mayo Clinic.ExpandLaunch map view
  • Distance: 480.3 mi
  • Duration: 11h 45m

What companies run services between Muscatine, IA, USA and Mayo Clinic, MN, USA?

There is no direct connection from Muscatine to Mayo Clinic. However, you can take the taxi to Iowa City, take the bus to Des Moines, take the bus to Minneapolis Bus Station, take the bus to Rochester, then walk to Mayo Clinic. Alternatively, you can take a vehicle from Muscatine to Mayo Clinic via Galesburg Amtrak Station, Chicago Union Station, St. Paul-Minneapolis, St. Paul, and Rochester in around 15h 35m.

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