There are 4 ways to get from Muscle Shoals to Knoxville by taxi, plane, bus (Greyhound, Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi to Huntsville International Airport-Carl T Jones Field, fly
best- Take the taxi from Muscle Shoals to Huntsville International Airport-Carl T Jones Field (HSV)taxi
- Fly from Huntsville International Airport-Carl T Jones Field (HSV) to Mcghee Tyson Airport (TYS)plane HSV - TYS
4h 32m$338–1,227Drive 278.2 mi
cheapest- Drive from Muscle Shoals to Knoxvillecar 278.2 mi
5h 1m$51–74Bus
- Take the bus from Florence to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to New York City Chinatownbus
- Take the bus from New York, NY to Knoxville, TNbus Ny
43h 14m$318–448Drive to Nashville, fly
- Drive from Muscle Shoals to Nashville-Airport-BNAcar
- Fly from Nashville (BNA) to Mcghee Tyson Airport (TYS)plane BNA - TYS
3h 52m$188–953
Huntsville International Airport-Carl T Jones Field (HSV) to Mcghee Tyson Airport (TYS) flights
Comparing Your Travel Options
The cheapest way to get from Muscle Shoals to Knoxville is to drive which costs $50 - $75 and takes 5h 1m.
The fastest way to get from Muscle Shoals to Knoxville is to drive and fly which takes 3h 52m and costs $180 - $1,000.
No, there is no direct bus from Muscle Shoals to Knoxville station. However, there are services departing from Florence and arriving at Knoxville Station Hall of Fame via Atlanta Bus Station, New York, NY, Walmart and Fountain City Superstop. The journey, including transfers, takes approximately 43h 14m.
The distance between Muscle Shoals and Knoxville is 248 miles. The road distance is 279.8 miles.
The best way to get from Muscle Shoals to Knoxville without a car is to bus which takes 43h 14m and costs $310 - $450.
It takes approximately 4h 32m to get from Muscle Shoals to Knoxville, including transfers.
Muscle Shoals to Knoxville bus services, operated by Greyhound USA, depart from Florence station.
Muscle Shoals to Knoxville bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Knoxville is 1h ahead of Muscle Shoals. It is currently 9:29 PM in Muscle Shoals and 10:29 PM in Knoxville.
Yes, the driving distance between Muscle Shoals to Knoxville is 280 miles. It takes approximately 5h 1m to drive from Muscle Shoals to Knoxville.
What companies run services between Muscle Shoals, AL, USA and Knoxville, TN, USA?
You can take a vehicle from Muscle Shoals to Knoxville Station Hall of Fame via Florence, Atlanta Bus Station, New York, NY, Knoxville, TN, Walmart, and Fountain City Superstop in around 43h 14m.
- Website
- southwest.com
Flights from Nashville to Mcghee Tyson Airport
- Ave. Duration
- 57 min
- When
- Every day
- Estimated price
- $110–850
- Website
- delta.com
Flights from Huntsville International Airport-Carl T Jones Field to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 3h 32m
- When
- Every day
- Estimated price
- $150–1,000
Flights from Huntsville International Airport-Carl T Jones Field to Mcghee Tyson Airport via Detroit
- Ave. Duration
- 4h 45m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $270–1,400
- Website
- aa.com
Flights from Huntsville International Airport-Carl T Jones Field to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 3h 55m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $180–1,100
- Website
- united.com
Flights from Huntsville International Airport-Carl T Jones Field to Mcghee Tyson Airport via Washington Dulles
- Ave. Duration
- 5h 6m
- When
- Every day
- Estimated price
- $280–1,400
- Website
- allegiantair.com
Flights from Huntsville International Airport-Carl T Jones Field to Mcghee Tyson Airport via St. Petersburg
- Ave. Duration
- 4h 58m
- When
- Thursday
- Estimated price
- $290–1,500
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Florence to Atlanta Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- Once daily
- Estimated price
- $55–85
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Atlanta Bus Station to New York City Chinatown
- Ave. Duration
- 18h 5m
- Frequency
- 3 times a day
- Estimated price
- $140–220
- Schedules at
- Flixbus USA
- Phone
- +1 615-939-8887
- [email protected]
- Website
- New York to Tennessee Bus
Bus from New York, NY to Knoxville, TN
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $95–110
- Website
- New York to Tennessee Bus
- Adult One-way
- $95–110
- Ave. Duration
- 1h 6m
- Estimated price
- $130–160
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Booking & Getting There
There are 318+ hotels available in Knoxville.



