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How to get fromMyrtle Beach Airport (MYR) to Buffaloby plane, bus (Greyhound, Flixbus), bus, train, or car

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There are 6 ways to get from Myrtle Beach Airport (MYR) to Buffalo by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Buffalo Niagara International Airport

    best
    1. Fly from Myrtle Beach (MYR) to Buffalo Niagara International Airport (BUF)plane plane MYR - BUF
    4h 30m
    $101–539

  2. Bus

    1. Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus bus
    2. Take the bus from Wilmington Cape Fear Public Transit to Raleigh Bus Stationbus bus
    3. Take the bus from Raleigh Bus Station to Newark Penn Stationbus bus
    4. Take the bus from Newark Penn Station to Buffalobus bus
    24h 46m
    $173–336

  3. Bus, train via New York

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    2. Take the train from Charleston Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train
    27h 9m
    $397–813

  4. Drive 761.1 mi

    1. Drive from Myrtle Beach Airport (MYR) to Buffalocar car 761.1 mi
    15h 36m
    $139–201

  5. Fly to Rochester, bus

    1. Fly from Myrtle Beach (MYR) to Rochester (ROC)plane plane MYR - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    4h 30m
    $212–739

  6. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Raleigh Bus Stationbus bus
    2. Take the train from Raleigh Union Station to Pittsburgh Amtrak Stationtrain train
    3. Take the bus from Pittsburgh, Pa to Buffalo, Nybus bus 510
    35h 7m
    $314–726

Myrtle Beach (MYR) to Buffalo Niagara International Airport (BUF) flights

Calendar88Weekly Planes
Duration5h 10mAverage Duration
Ticket$98Cheapest Price
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Questions & Answers

Map of how to get from Myrtle Beach Airport (MYR) to Buffalo.ExpandLaunch map view
  • Distance: 653.4 mi
  • Duration: 4h 30m

What companies run services between Myrtle Beach Airport (MYR), USA and Buffalo, NY, USA?

Southwest Airlines, United Airlines, and two other airlines fly from Myrtle Beach (MYR) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a vehicle from Myrtle Beach Airport (MYR) to Buffalo via Myrtle Beach Bus Station, Wilmington Cape Fear Public Transit, Raleigh Bus Station, and Newark Penn Station in around 24h 46m.

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