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How to get fromMyrtle Beach Airport (MYR) to Knoxvilleby plane, car, bus, shuttle, or rideshare

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There are 5 ways to get from Myrtle Beach Airport (MYR) to Knoxville by plane, car, bus, shuttle, or rideshare

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Myrtle Beach

    best
    1. Fly from Myrtle Beach (MYR) to Mcghee Tyson Airport (TYS)plane plane MYR - TYS
    3h 42m
    $143–622

  2. Drive 401 mi

    cheapest
    1. Drive from Myrtle Beach Airport (MYR) to Knoxvillecar car 401 mi
    7h 36m
    $74–106

  3. Drive to Florence Regional Airport, fly

    1. Drive from Myrtle-Beach-Airport-MYR to Florence Regional Airport (FLO)car car
    2. Fly from Florence Regional Airport (FLO) to Mcghee Tyson Airport (TYS)plane plane FLO - TYS
    5h 21m
    $157–687

  4. Bus, shuttle, drive

    1. Take the bus from Myrtle Beach Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Airport to ASU Peacock Hall Boonebus bus
    4. Take a shuttle bus from Boone to Black Bear Resortshuttle bus
    5. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    6. Drive from Hot Springs to Knoxvillecar car
    14h 51m
    $395–464

  5. Airport Transfer

    1. Take the rideshare from Myrtle Beach-MYR to Knoxvillerideshare rideshare 401 mi
    7h 36m

Myrtle Beach (MYR) to Mcghee Tyson Airport (TYS) flights

Calendar67Weekly Planes
Duration4h 39mAverage Duration
Ticket$87Cheapest Price
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Questions & Answers

Map of how to get from Myrtle Beach Airport (MYR) to Knoxville.ExpandLaunch map view
  • Distance: 335.7 mi
  • Duration: 3h 42m

What companies run services between Myrtle Beach Airport (MYR), USA and Knoxville, TN, USA?

American Airlines, Delta, and two other airlines fly from Myrtle Beach (MYR) to Mcghee Tyson Airport (TYS) every 3 hours.

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