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How to get fromMyrtle Beach Bus Station to Chicagoby plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

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There are 6 ways to get from Myrtle Beach Bus Station to Chicago by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Chicago Midway International Airport

    best
    1. Fly from Myrtle Beach (MYR) to Chicago Midway International Airport (MDW)plane plane MYR - MDW
    2h 58m
    $84–399

  2. Fly to Chicago O'Hare International Airport

    cheapest
    1. Fly from Myrtle Beach (MYR) to Chicago O'Hare International Airport (ORD)plane plane MYR - ORD
    3h 32m
    $64–309

  3. Bus via Atlanta

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus Greyhound US0641S
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus Greyhound US0100
    25h 55m
    $176–297

  4. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the train from Fayetteville Amtrak Station to Petersburg Amtrak Stationtrain train
    3. Take the train from Petersburg Amtrak Station to Chicago Union Stationtrain train
    30h 4m
    $617–1,001

  5. Drive  895.3 mi

    1. Drive from Myrtle Beach Bus Station to Chicagocar car 895.3 mi
    16h 29m
    $164–236

  6. Bus

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the bus from Fayetteville to Winston-Salembus bus
    3. Take the bus from Winston Salem to Columbusbus bus
    4. Take the bus from Columbus to Chicagobus bus
    26h 55m
    $121–246

Myrtle Beach Bus Station to Chicago by bus

Calendar7Weekly Buses
Duration25h 55mAverage Duration
Ticket$176Cheapest Price
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Comparing Your Travel Options

Map of how to get from Myrtle Beach Bus Station to Chicago.ExpandLaunch map view
  • Distance: 751.8 mi
  • Duration: 2h 58m

What companies run services between Myrtle Beach Bus Station, SC, USA and Chicago, IL, USA?

Southwest Airlines and Delta fly from Myrtle Beach (MYR) to Chicago Midway International Airport (MDW) 3 times a day. Alternatively, you can take a bus from Myrtle Beach Bus Station to Chicago Bus Station via Atlanta Bus Station in around 25h 55m.

Airlines
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Bus operators

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