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How to get fromMyrtle Beach to Clevelandby plane, bus (Greyhound), bus, train, or car

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There are 6 ways to get from Myrtle Beach to Cleveland by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Myrtle Beach (MYR) to Cleveland-Hopkins International Airport (CLE)plane plane MYR - CLE
    4h 23m
    $90–467

  2. Bus via Camden

    1. Take the bus from Myrtle Beach Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Charleston, WVbus bus
    4. Take the bus from Charleston, WV to Cleveland, OHbus bus
    19h 25m
    $101–194

  3. Bus, train via Raleigh

    1. Take the bus from Myrtle Beach Bus Station to Raleigh Bus Stationbus bus Greyhound US0645S
    2. Take the train from Raleigh Union Station to Cleveland Amtraktrain train Floridian
    23h 30m
    $218–487

  4. Drive  660.4 mi

    1. Drive from Myrtle Beach to Clevelandcar car 660.4 mi
    12h 18m
    $121–175

  5. Bus

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the bus from Fayetteville to Winston-Salembus bus
    3. Take the bus from Winston Salem to Charlestonbus bus
    4. Take the bus from Charleston to Akronbus bus
    5. Take the bus from Robert K Pfaff Transit Center - Akron to W. Prospect Ave & Superior Avebus bus 61
    20h 31m
    $95–199

  6. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    2. Take the train from Charleston Amtrak Station to Petersburg Amtrak Stationtrain train
    3. Take the train from Petersburg Amtrak Station to Cleveland Amtraktrain train
    25h 5m
    $246–574

Myrtle Beach to Cleveland by bus

Calendar7Weekly Buses
Duration19h 25mAverage Duration
Ticket$101Cheapest Price
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Comparing Your Travel Options

Map of how to get from Myrtle Beach to Cleveland.ExpandLaunch map view
  • Distance: 571.5 mi
  • Duration: 4h 23m

What companies run services between Myrtle Beach, SC, USA and Cleveland, OH, USA?

Southwest Airlines, American Airlines, and Delta fly from Myrtle Beach (MYR) to Cleveland-Hopkins International Airport (CLE) hourly. Alternatively, you can take a bus from Myrtle Beach Bus Station to Cleveland, OH via Camden, Charlotte Bus Station, and Charleston, WV in around 19h 25m.

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Need to know: Greyhound

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