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How to get fromMyrtle Beach to Destinby plane, bus, taxi, or car

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There are 5 ways to get from Myrtle Beach to Destin by plane, bus, taxi, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Destin–Fort Walton Beach Airport

    best
    1. Fly from Myrtle Beach (MYR) to Destin–Fort Walton Beach Airport (VPS)plane plane MYR - VPS
    4h 7m
    $107–409

  2. Drive  578.7 mi

    cheapest
    1. Drive from Myrtle Beach to Destincar car 578.7 mi
    11h 56m
    $106–153

  3. Bus, taxi

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to La Grange Bus Stationbus bus
    3. Take the bus from La Grange Bus Station to Mobilebus bus
    4. Take the bus from Loxley to Crestviewbus bus
    5. Take the taxi from Crestview to Destintaxi taxi
    18h 43m
    $267–359

  4. Fly to Northwest Florida Beaches International Airport, taxi

    1. Fly from Myrtle Beach (MYR) to Northwest Florida Beaches International Airport (ECP)plane plane MYR - ECP
    2. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    5h 15m
    $207–534

  5. Fly to Pensacola International Airport, taxi

    1. Fly from Myrtle Beach (MYR) to Pensacola International Airport (PNS)plane plane MYR - PNS
    2. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    5h 22m
    $177–444

Myrtle Beach (MYR) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar57Weekly Planes
Duration5h 15mAverage Duration
Ticket$58Cheapest Price
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Comparing Your Travel Options

Map of how to get from Myrtle Beach to Destin.ExpandLaunch map view
  • Distance: 516.5 mi
  • Duration: 4h 7m

What companies run services between Myrtle Beach, SC, USA and Destin, FL, USA?

Delta, American Airlines, and Southwest Airlines fly from Myrtle Beach (MYR) to Destin–Fort Walton Beach Airport (VPS) every 4 hours.

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