Rome2Rio

How to get fromMyrtle Beach to Fort Myersby plane, bus, train, car, or bus (Greyhound, Flixbus)

Find Transport to Fort Myers

See all options

There are 9 ways to get from Myrtle Beach to Fort Myers by plane, bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Myrtle Beach to Ft. Myers

    best
    1. Fly from Myrtle Beach (MYR) to Ft. Myers (RSW)plane plane MYR - RSW
    5h 53m
    $95–449

  2. Bus, train via Jacksonville

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    2. Take the train from Charleston Amtrak Station to Jacksonvilletrain train
    3. Take the bus from Jacksonville to Wildwood Amtrak Stationbus bus
    4. Take the bus from Wildwood to Fort Myersbus bus
    18h 12m
    $180–318

  3. Drive  623 mi

    1. Drive from Myrtle Beach to Fort Myerscar car 623 mi
    11h 41m
    $114–165

  4. Fly Myrtle Beach to Fort Lauderdale–Hollywood International Airport, bus

    1. Fly from Myrtle Beach (MYR) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane MYR - FLL
    2. Take the bus from Fort Lauderdale International Airport to Fort Myers Bus Stopbus bus
    5h 33m
    $171–479

  5. Fly Myrtle Beach to Tampa, bus

    1. Fly from Myrtle Beach (MYR) to Tampa (TPA)plane plane MYR - TPA
    2. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    6h 58m
    $123–441

  6. Bus to Wilmington International Airport, fly to Ft. Myers

    1. Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus bus
    2. Fly from Wilmington International Airport (ILM) to Ft. Myers (RSW)plane plane ILM - RSW
    6h 46m
    $249–645

  7. Fly Myrtle Beach to Orlando, bus

    1. Fly from Myrtle Beach (MYR) to Orlando (MCO)plane plane MYR - MCO
    2. Take the bus from Orlando to Fort Myers Bus Stopbus bus
    9h 9m
    $144–311

  8. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    2. Take the train from Charleston Amtrak Station to Winter Park Amtrak Stationtrain train
    3. Take the bus from Orlando to Fort Myers Bus Stopbus bus
    19h 18m
    $147–315

  9. Bus

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Tampa Bus Stationbus bus
    3. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    22h 20m
    $141–250

Myrtle Beach to Fort Myers by bus and train

Calendar7Weekly Services
Duration19h 18mAverage Duration
Ticket$147Cheapest Price
See schedules

Questions & Answers

Map of how to get from Myrtle Beach to Fort Myers.ExpandLaunch map view
  • Distance: 540 mi
  • Duration: 5h 53m

What companies run services between Myrtle Beach, SC, USA and Fort Myers, FL, USA?

Delta, American Airlines, and Southwest Airlines fly from Myrtle Beach (MYR) to Ft. Myers (RSW) every 4 hours. Alternatively, you can take a bus from Myrtle Beach Bus Station to Fort Myers Bus Stop via Atlanta Bus Station and Tampa Bus Station in around 22h 20m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers