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How to get fromMyrtle Beach to Fort Myersby plane, bus, train, car, or bus (Greyhound, Flixbus)

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There are 9 ways to get from Myrtle Beach to Fort Myers by plane, bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Myrtle Beach to Ft. Myers

    best
    1. Fly from Myrtle Beach (MYR) to Ft. Myers (RSW)plane plane MYR - RSW
    5h 58m
    $355–619

  2. Fly Myrtle Beach to Tampa, bus

    cheapest
    1. Fly from Myrtle Beach (MYR) to Tampa (TPA)plane plane MYR - TPA
    2. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    6h 23m
    $113–601

  3. Bus, train via Jacksonville

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    2. Take the train from Charleston Amtrak Station to Jacksonvilletrain train
    3. Take the bus from Jacksonville to Wildwood Amtrak Stationbus bus
    4. Take the bus from Wildwood to Fort Myersbus bus
    18h 12m
    $201–350

  4. Drive 623 mi

    1. Drive from Myrtle Beach to Fort Myerscar car 623 mi
    11h 41m
    $114–165

  5. Fly Myrtle Beach to Fort Lauderdale–Hollywood International Airport, bus

    1. Fly from Myrtle Beach (MYR) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane MYR - FLL
    2. Take the bus from Fort Lauderdale International Airport to Fort Myers Bus Stopbus bus
    5h 27m
    $163–509

  6. Bus to Wilmington International Airport, fly to Ft. Myers

    1. Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus bus
    2. Fly from Wilmington International Airport (ILM) to Ft. Myers (RSW)plane plane ILM - RSW
    6h 45m
    $276–612

  7. Fly Myrtle Beach to Orlando, bus

    1. Fly from Myrtle Beach (MYR) to Orlando (MCO)plane plane MYR - MCO
    2. Take the bus from Orlando to Fort Myers Bus Stopbus bus
    8h 59m
    $139–396

  8. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    2. Take the train from Charleston Amtrak Station to Winter Park Amtrak Stationtrain train
    3. Take the bus from Orlando to Fort Myers Bus Stopbus bus
    19h 6m
    $173–352

  9. Bus

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    2. Take the bus from Charleston Bus Station to Savannah Bus Stationbus bus
    3. Take the bus from Savannah Bus Station to Tampa Bus Stationbus bus
    4. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    20h 20m
    $137–230

Myrtle Beach to Fort Myers by bus and train

Calendar7Weekly Services
Duration19h 6mAverage Duration
Ticket$173Cheapest Price
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Questions & Answers

Map of how to get from Myrtle Beach to Fort Myers.ExpandLaunch map view
  • Distance: 540 mi
  • Duration: 5h 58m

What companies run services between Myrtle Beach, SC, USA and Fort Myers, FL, USA?

Delta, American Airlines, and Southwest Airlines fly from Myrtle Beach (MYR) to Ft. Myers (RSW) every 4 hours. Alternatively, you can take a bus from Myrtle Beach Bus Station to Fort Myers Bus Stop via Charleston Bus Station, Savannah Bus Station, and Tampa Bus Station in around 20h 20m.

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