There are 7 ways to get from Myrtle Beach to Frederick by plane, bus, bus (Greyhound, Flixbus), train, car, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Baltimore-Washington International Airport, bus
best- Fly from Myrtle Beach (MYR) to Baltimore-Washington International Airport (BWI)plane MYR - BWI
- Take the bus from Baltimore Airport to Frederick Bus Stationbus
3h 41m$382–774Bus, train
cheapest- Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus
- Take the bus from Fayetteville Bus Station to Washington Union Stationbus
- Take the train from Washington Union Station to FREDERICK MARC wbtrain
13h 11m$71–124Bus
- Take the bus from Myrtle Beach Bus Station to Raleigh Bus Stationbus
- Take the bus from Raleigh Bus Station to Washington Union Stationbus
- Take the bus from Washington Union Station to Frederick Bus Stationbus
12h$76–129Bus, train via Fayetteville
- Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus
- Take the train from Fayetteville Amtrak Station to Washington Union Stationtrain
- Take the train from Washington Union Station to FREDERICK MARC wbtrain
13h 9m$106–239Drive 454.9 mi
- Drive from Myrtle Beach to Frederickcar 454.9 mi
8h 30m$83–120Fly to Ronald Reagan Washington National Airport, bus
- Fly from Myrtle Beach (MYR) to Ronald Reagan Washington National Airport (DCA)plane MYR - DCA
- Take the bus from SHADY GROVE & station to Frederick Marc Stationbus
4h 18m$88–493Fly to Washington Dulles International Airport, subway, bus
- Fly from Myrtle Beach (MYR) to Washington Dulles International Airport (IAD)plane MYR - IAD
- Take the subway from Washington Dulles International Airport, Silver Line Center Platform to Metro Center, Blue/Orange/Silver Line Center Platformsubway
- Take the bus from SHADY GROVE & station to Frederick Marc Stationbus
7h 32m$78–392
Myrtle Beach to Frederick by bus
Comparing Your Travel Options
The cheapest way to get from Myrtle Beach to Frederick is to bus and train which costs $70 - $130 and takes 13h 11m.
The fastest way to get from Myrtle Beach to Frederick is to fly and bus which takes 3h 41m and costs $380 - $800.
No, there is no direct bus from Myrtle Beach station to Frederick station. However, there are services departing from Myrtle Beach Bus Station and arriving at Frederick Bus Station via Raleigh Bus Station and Washington Union Station. The journey, including transfers, takes approximately 12h.
The distance between Myrtle Beach and Frederick is 456 miles. The road distance is 457.5 miles.
The best way to get from Myrtle Beach to Frederick without a car is to bus which takes 12h and costs $75 - $130.
It takes approximately 3h 41m to get from Myrtle Beach to Frederick, including transfers.
Myrtle Beach to Frederick bus services, operated by Greyhound USA, depart from Myrtle Beach Bus Station.
Myrtle Beach to Frederick bus services, operated by Greyhound USA, arrive at Raleigh Bus Station.
Yes, the driving distance between Myrtle Beach to Frederick is 458 miles. It takes approximately 8h 30m to drive from Myrtle Beach to Frederick.
Book your Myrtle Beach to Frederick bus tickets online with Omio and FlixBus.
What companies run services between Myrtle Beach, SC, USA and Frederick, MD, USA?
You can take a bus from Myrtle Beach Bus Station to Frederick Bus Station via Raleigh Bus Station and Washington Union Station in around 12h.
- Website
- aa.com
Flights from Myrtle Beach to Ronald Reagan Washington National Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $70–470
Flights from Myrtle Beach to Ronald Reagan Washington National Airport via Charlotte
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $80–500
Flights from Myrtle Beach to Washington Dulles International Airport via Charlotte
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $60–370
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Fayetteville Amtrak Station to Washington Union Station
- Ave. Duration
- 6h 28m
- Frequency
- Twice daily
- Estimated price
- $80–190
- Website
- Amtrak
- Phone
- +1 410-912-6000
- [email protected]
- Website
- BayRunner Shuttle
Bus from Baltimore Airport to Frederick Bus Station
- Ave. Duration
- 1h 15m
- Frequency
- 4 times a day
- Estimated price
- $70–110
- Schedules at
- BayRunner Shuttle
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Booking & Getting There
There are 65+ hotels available in Frederick.








