There are 7 ways to get from Myrtle Beach to Gainesville by plane, bus, train, bus (Greyhound, Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Gainesville Regional Airport
best- Fly from Myrtle Beach (MYR) to Gainesville Regional Airport (GNV)plane MYR - GNV
4h 50m$69–336Bus, train
- Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus
- Take the train from Charleston Amtrak Station to Jacksonvilletrain
- Take the bus from Jacksonville to Gainesvillebus
11h 11m$94–206Bus
- Take the bus from Myrtle Beach Bus Station to Camdenbus
- Take the bus from Camden to Jacksonvillebus
- Take the bus from Jacksonville to Gainesvillebus
14h 14m$76–143Drive 395.2 mi
- Drive from Myrtle Beach to Gainesvillecar 395.2 mi
7h 34m$73–105Fly to Orlando, bus
- Fly from Myrtle Beach (MYR) to Orlando (MCO)plane MYR - MCO
- Take the bus from Orlando - RedCoach Station, FL to University of Florida - 1956 Gale Lemerand Drbus
5h 29m$143–341Fly to Jacksonville, bus
- Fly from Myrtle Beach (MYR) to Jacksonville (JAX)plane MYR - JAX
- Take the bus from Jacksonville to Gainesvillebus
7h 26m$77–373Fly to Tampa, bus
- Fly from Myrtle Beach (MYR) to Tampa (TPA)plane MYR - TPA
- Take the bus from Tampa Bus Station to Gainesvillebus
6h 1m$107–306
Myrtle Beach to Gainesville by bus and train
Questions & Answers
The cheapest way to get from Myrtle Beach to Gainesville is to drive which costs $70 - $110 and takes 7h 34m.
The fastest way to get from Myrtle Beach to Gainesville is to fly which takes 4h 50m and costs $65 - $340.
No, there is no direct bus from Myrtle Beach station to Gainesville. However, there are services departing from Myrtle Beach Bus Station and arriving at Gainesville via Camden and Jacksonville. The journey, including transfers, takes approximately 14h 14m.
The distance between Myrtle Beach and Gainesville is 351 miles. The road distance is 397.6 miles.
The best way to get from Myrtle Beach to Gainesville without a car is to bus and train which takes 11h 11m and costs $90 - $210.
It takes approximately 4h 50m to get from Myrtle Beach to Gainesville, including transfers.
Myrtle Beach to Gainesville bus services, operated by Greyhound USA, depart from Myrtle Beach Bus Station.
The best way to get from Myrtle Beach to Gainesville is to fly which takes 4h 50m and costs $65 - $340. Alternatively, you can bus, which costs $75 - $150 and takes 14h 14m.
Myrtle Beach to Gainesville bus services, operated by Greyhound USA, arrive at Camden station.
Yes, the driving distance between Myrtle Beach to Gainesville is 398 miles. It takes approximately 7h 34m to drive from Myrtle Beach to Gainesville.
What companies run services between Myrtle Beach, SC, USA and Gainesville, FL, USA?
Delta and American Airlines fly from Myrtle Beach (MYR) to Gainesville Regional Airport (GNV) 5 times a day. Alternatively, you can take a bus from Myrtle Beach Bus Station to Gainesville via Camden and Jacksonville in around 14h 14m.
- Website
- aa.com
Flights from Myrtle Beach to Gainesville Regional Airport via Charlotte
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $55–320
Flights from Myrtle Beach to Orlando via Charlotte
- Ave. Duration
- 3h 54m
- When
- Monday to Saturday
- Estimated price
- $60–340
Flights from Myrtle Beach to Jacksonville via Charlotte
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- $55–340
Flights from Myrtle Beach to Tampa via Charlotte
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $70–370
- Website
- delta.com
Flights from Myrtle Beach to Gainesville Regional Airport via Atlanta
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $60–340
Flights from Myrtle Beach to Orlando via Atlanta
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $70–360
Flights from Myrtle Beach to Jacksonville via Atlanta
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $65–360
Flights from Myrtle Beach to Tampa via Atlanta
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $70–380
- Website
- southwest.com
Flights from Myrtle Beach to Jacksonville via Nashville
- Ave. Duration
- 5h 13m
- When
- Sunday, Tuesday, Wednesday, Monday, Thursday, and Friday
- Estimated price
- $90–430
Flights from Myrtle Beach to Jacksonville via Baltimore
- Ave. Duration
- 5h 5m
- When
- Sunday
- Estimated price
- $95–450
- Website
- flybreeze.com
Flights from Myrtle Beach to Orlando
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $100–270
Flights from Myrtle Beach to Jacksonville via Fort Lauderdale
- Ave. Duration
- 4h 24m
- When
- Thursday and Sunday
- Estimated price
- $150–900
Flights from Myrtle Beach to Tampa
- Ave. Duration
- 1h 37m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $75–260
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Charleston Amtrak Station to Jacksonville
- Ave. Duration
- 4h 28m
- Frequency
- Once daily
- Estimated price
- $70–160
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Myrtle Beach Bus Station to Charleston Bus Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $14–28
- Website
- Greyhound
Bus from Myrtle Beach Bus Station to Camden
- Ave. Duration
- 3h 15m
- Frequency
- Once daily
- Estimated price
- $17–35
- Website
- Greyhound
Bus from Camden to Jacksonville
- Ave. Duration
- 7h 30m
- Frequency
- Once daily
- Estimated price
- $50–95
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Jacksonville to Gainesville
- Ave. Duration
- 1h 29m
- Frequency
- 6 times a week
- Estimated price
- $9–16
- Schedules at
- Flixbus USA
Bus from Jacksonville to Gainesville
- Ave. Duration
- 1h 29m
- Frequency
- 6 times a week
- Estimated price
- $9–16
- Schedules at
- Flixbus USA
Bus from Jacksonville to Gainesville
- Ave. Duration
- 1h 29m
- Frequency
- 6 times a week
- Estimated price
- $9–16
- Schedules at
- Flixbus USA
Bus from Tampa Bus Station to Gainesville
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $18–30
- Schedules at
- Flixbus USA
- Phone
- +1 877 733 0724
- Website
- RedCoach
Bus from Orlando - RedCoach Station, FL to University of Florida - 1956 Gale Lemerand Dr
- Ave. Duration
- 2h 20m
- Frequency
- 4 times a day
- Estimated price
- $29–55
- Website
- RedCoach
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