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How to get fromMyrtle Beach to Indianaby plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

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There are 9 ways to get from Myrtle Beach to Indiana by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Evansville

    best
    1. Fly from Myrtle Beach (MYR) to Evansville (EVV)plane plane MYR - EVV
    3h 58m
    $91–387

  2. Fly to Chicago O'Hare International Airport, train

    cheapest
    1. Fly from Myrtle Beach (MYR) to Chicago O'Hare International Airport (ORD)plane plane MYR - ORD
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    4h 36m
    $72–329

  3. Bus via Atlanta

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus Greyhound US0641S
    2. Take the bus from Atlanta Bus Station to Indianapolisbus bus FlixBus 2512
    21h 35m
    $138–220

  4. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the train from Fayetteville Amtrak Station to Alexandriatrain train
    3. Take the train from Alexandria to Indianapolistrain train
    28h 53m
    $269–647

  5. Drive  718.7 mi

    1. Drive from Myrtle Beach to Indianapoliscar car 718.7 mi
    13h 27m
    $132–190

  6. Fly to Indianapolis

    1. Fly from Myrtle Beach (MYR) to Indianapolis (IND)plane plane MYR - IND
    5h 18m
    $99–516

  7. Fly to Fort Wayne International Airport

    1. Fly from Myrtle Beach (MYR) to Fort Wayne International Airport (FWA)plane plane MYR - FWA
    4h 45m
    $107–419

  8. Fly to Chicago Midway International Airport, train

    1. Fly from Myrtle Beach (MYR) to Chicago Midway International Airport (MDW)plane plane MYR - MDW
    2. Take the train from Museum Campus/11th St. to Gary Metro Centertrain train
    4h 5m
    $87–399

  9. Bus

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the bus from Fayetteville to Winston-Salembus bus
    3. Take the bus from Winston Salem to Columbusbus bus
    4. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Richmond, INbus bus
    5. Take the bus from Richmond Bsb, IN to Indianapolis, INbus bus
    23h 15m
    $104–247

Myrtle Beach to Indiana by bus

Calendar7Weekly Buses
Duration21h 35mAverage Duration
Ticket$138Cheapest Price
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Comparing Your Travel Options

Map of how to get from Myrtle Beach to Indiana.ExpandLaunch map view
  • Distance: 578.1 mi
  • Duration: 3h 58m

What companies run services between Myrtle Beach, SC, USA and Indiana, USA?

Delta and American Airlines fly from Myrtle Beach (MYR) to Evansville (EVV) every 4 hours. Alternatively, you can take a bus from Myrtle Beach Bus Station to Indianapolis via Atlanta Bus Station in around 21h 35m.

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