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How to get fromMyrtle Beach to Indianapolisby plane, bus (Greyhound, Flixbus), bus, train, or car

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There are 5 ways to get from Myrtle Beach to Indianapolis by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Myrtle Beach (MYR) to Indianapolis (IND)plane plane MYR - IND
    5h 18m
    $94–476

  2. Bus

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus Greyhound US0641S
    2. Take the bus from Atlanta Bus Station to Indianapolisbus bus FlixBus 2512
    21h 35m
    $134–242

  3. Bus, train via Arlington

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the train from Fayetteville Amtrak Station to Alexandriatrain train
    3. Take the train from Alexandria to Indianapolistrain train
    34h 53m
    $362–768

  4. Drive 718.6 mi

    1. Drive from Myrtle Beach to Indianapoliscar car 718.6 mi
    13h 28m
    $132–190

  5. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the bus from Fayetteville to Winston-Salembus bus
    3. Take the bus from Winston Salem(Trans Center) to Ashlandbus bus
    4. Take the train from Ashland Amtrak Station to Indianapolistrain train
    28h 46m
    $185–403

Myrtle Beach to Indianapolis by bus

Calendar7Weekly Buses
Duration21h 35mAverage Duration
Ticket$134Cheapest Price
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Questions & Answers

Map of how to get from Myrtle Beach to Indianapolis.ExpandLaunch map view
  • Distance: 600.8 mi
  • Duration: 5h 18m

What companies run services between Myrtle Beach, SC, USA and Indianapolis, IN, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Myrtle Beach (MYR) to Indianapolis (IND) every 3 hours. Alternatively, you can take a bus from Myrtle Beach Bus Station to Indianapolis via Atlanta Bus Station in around 21h 35m.

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