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How to get fromMyrtle Beach to Jacksonvilleby bus, train, bus (Greyhound), car, or plane

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There are 5 ways to get from Myrtle Beach to Jacksonville by bus, train, bus (Greyhound), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus Greyhound US0645S / ...
    2. Take the train from Charleston Amtrak Station to Jacksonvilletrain train Silver Meteor
    8h 22m
    $77–177

  2. Drive  331.6 mi

    cheapest
    1. Drive from Myrtle Beach to Jacksonvillecar car 331.6 mi
    6h 16m
    $61–88

  3. Bus (Greyhound)

    1. Take the bus from Myrtle Beach Bus Station to Camdenbus bus Greyhound US0641S
    2. Take the bus from Camden to Jacksonvillebus bus Greyhound US0644S
    11h 45m
    $68–114

  4. Fly to Jacksonville

    1. Fly from Myrtle Beach (MYR) to Jacksonville (JAX)plane plane MYR - JAX
    5h 37m
    $73–397

  5. Fly to Brunswick Golden Isles Airport, bus

    1. Fly from Myrtle Beach (MYR) to Brunswick Golden Isles Airport (BQK)plane plane MYR - BQK
    2. Take the bus from Brunswick to Jacksonvillebus bus
    8h 23m
    $92–399

Myrtle Beach to Jacksonville by bus and train

Calendar7Weekly Services
Duration8h 22mAverage Duration
Ticket$77Cheapest Price
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Comparing Your Travel Options

Map of how to get from Myrtle Beach to Jacksonville.ExpandLaunch map view
  • Distance: 353.3 mi
  • Duration: 8h 22m

What companies run services between Myrtle Beach, SC, USA and Jacksonville, FL, USA?

You can take a bus from Myrtle Beach Bus Station to Jacksonville via Camden in around 11h 45m. Alternatively, Delta, Southwest Airlines, and American Airlines fly from Myrtle Beach (MYR) to Jacksonville (JAX) every 2 hours.

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Need to know: Greyhound

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