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How to get fromMyrtle Beach to Jacksonvilleby plane, bus, train, bus (Greyhound), or car

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There are 5 ways to get from Myrtle Beach to Jacksonville by plane, bus, train, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Jacksonville

    best
    1. Fly from Myrtle Beach (MYR) to Jacksonville (JAX)plane plane MYR - JAX
    5h 13m
    $73–367

  2. Drive 331.6 mi

    cheapest
    1. Drive from Myrtle Beach to Jacksonvillecar car 331.6 mi
    6h 16m
    $61–88

  3. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus Greyhound US0645S / ...
    2. Take the train from Charleston Amtrak Station to Jacksonvilletrain train Silver Meteor
    8h 42m
    $80–179

  4. Bus (Greyhound)

    1. Take the bus from Myrtle Beach Bus Station to Camdenbus bus Greyhound US0641S
    2. Take the bus from Camden to Jacksonvillebus bus Greyhound US0644S
    11h 45m
    $62–121

  5. Fly to Brunswick Golden Isles Airport, bus

    1. Fly from Myrtle Beach (MYR) to Brunswick Golden Isles Airport (BQK)plane plane MYR - BQK
    2. Take the bus from Brunswick to Jacksonvillebus bus
    8h 22m
    $91–379

Myrtle Beach to Jacksonville by bus and train

Calendar7Weekly Services
Duration8h 42mAverage Duration
Ticket$80Cheapest Price
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Questions & Answers

Map of how to get from Myrtle Beach to Jacksonville.ExpandLaunch map view
  • Distance: 294 mi
  • Duration: 5h 13m

What companies run services between Myrtle Beach, SC, USA and Jacksonville, FL, USA?

American Airlines, Delta, and Southwest Airlines fly from Myrtle Beach (MYR) to Jacksonville (JAX) every 4 hours. Alternatively, you can take a bus from Myrtle Beach Bus Station to Jacksonville via Camden in around 11h 45m.

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